Pre_GI: BLASTP Hits

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Query: NC_010161:1368500:1383445 Bartonella tribocorum CIP 105476, complete genome

Start: 1383445, End: 1383795, Length: 351

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010161:432000:434103434103434453351Bartonella tribocorum CIP 105476, complete genomehelicase domain-containing protein3e-51199
NC_012846:929570:9295709295709344804911Bartonella grahamii as4aup, complete genomehelicase/methyltransferase9e-44175
NC_012846:1952178:1969434196943419744104977Bartonella grahamii as4aup, complete genome2e-42170
NC_012846:1778443:1797703179770318026804978Bartonella grahamii as4aup, complete genome2e-42170
NC_011958:976500:99589499589410007564863Rhodobacter sphaeroides KD131 chromosome 2, complete genomehypothetical protein5e-33139
NC_008686:50750:640066400664503498Paracoccus denitrificans PD1222 chromosome 1, complete sequencehypothetical protein3e-30130
NC_014844:442380:4507084507084555494842Desulfovibrio aespoeensis Aspo-2 chromosome, complete genometype III restriction protein res subunit2e-2097.4
NC_014153:3084356:3085256308525630902865031Thiomonas intermedia K12 chromosome, complete genometype III restriction protein res subunit2e-1891.3
NC_008341:29038:3215032150366914542Nitrosomonas eutropha C91 plasmid1, complete sequencetype III restriction enzyme, res subunit4e-1890.1
NC_017111:2032500:203907720390772039766690Acetobacter pasteurianus IFO 3283-32, complete genomeDNA helicase restriction enzyme Type III R subunit5e-1786.3
NC_017108:2032500:203902020390202039748729Acetobacter pasteurianus IFO 3283-12, complete genomeDNA helicase restriction enzyme Type III R subunit5e-1786.3
NC_017986:1862408:1867994186799418728954902Pseudomonas putida ND6 chromosome, complete genomehelicase domain-containing protein5e-1786.7
NC_007651:3560652:3581602358160235833321731Burkholderia thailandensis E264 chromosome I, complete sequencehelicase domain protein6e-1786.3
NC_017150:1940000:1942610194261019475174908Acetobacter pasteurianus IFO 3283-01-42C, complete genomeDNA helicase restriction enzyme Type III R subunit6e-1785.9
NC_017146:2035000:2037526203752620424334908Acetobacter pasteurianus IFO 3283-26, complete genomeDNA helicase restriction enzyme Type III R subunit6e-1785.9
NC_017121:2032500:2034846203484620397534908Acetobacter pasteurianus IFO 3283-07, complete genomeDNA helicase restriction enzyme Type III R subunit6e-1785.9
NC_013209:2032500:2034864203486420397714908Acetobacter pasteurianus IFO 3283-01, complete genomeDNA helicase restriction enzyme Type III R subunit6e-1785.9
NC_017125:2035000:2037514203751420423914878Acetobacter pasteurianus IFO 3283-22, complete genomeDNA helicase restriction enzyme Type III R subunit7e-1785.9
NC_017100:2035000:2037519203751920424114893Acetobacter pasteurianus IFO 3283-03, complete genomeDNA helicase restriction enzyme Type III R subunit7e-1785.9
NC_008095:2117952:2132683213268321376534971Myxococcus xanthus DK 1622, complete genomeputative restriction/modification enzyme1e-1684.7
NC_004578:20738:4744847448523584911Pseudomonas syringae pv. tomato str. DC3000, complete genomehelicase domain protein2e-1684.3
NC_009328:2905000:2918927291892729236874761Geobacillus thermodenitrificans NG80-2 chromosome, complete genomehypothetical protein4e-1683.2
NC_002937:2263763:2270961227096122757484788Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completeadenine specific DNA methyltransferase, putative6e-1682.8
NC_017098:1542284:1558173155817315630234851Spirochaeta africana DSM 8902 chromosome, complete genomeputative helicase3e-1477
NC_008229:1149480:1153745115374511553431599Helicobacter acinonychis str. Sheeba, complete genomehelicase6e-1476.3
NC_008752:620802:6280546280546328834830Acidovorax avenae subsp. citrulli AAC00-1, complete genometype III restriction enzyme, res subunit7e-1475.9
NC_014215:349917:3633313633313681124782Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,helicase7e-1372.8
NC_015578:2191000:2208590220859022135905001Treponema primitia ZAS-2 chromosome, complete genomeendonuclease and methylase LlaGI1e-1271.6
NC_015578:1038588:1050775105077510557544980Treponema primitia ZAS-2 chromosome, complete genomeendonuclease and methylase LlaGI2e-1271.2
NC_012724:2682154:2696731269673127014944764Burkholderia glumae BGR1 chromosome 1, complete genomeAdenine specific DNA methyltransferase, putative3e-1270.5
NC_007333:1559321:156620015662001566865666Thermobifida fusca YX, complete genomehypothetical protein1e-1168.6
NC_015152:2026049:2036181203618120410794899Spirochaeta sp. Buddy chromosome, complete genometype III restriction protein res subunit3e-1167.4
NC_009615:1734752:1779432177943217844264995Parabacteroides distasonis ATCC 8503 chromosome, complete genomehelicase4e-1166.6
NC_020133:5485528:5496869549686954989022034Mycobacterium liflandii 128FXT, complete genomeputative helicase6e-1166.2
NC_003450:3266604:3276669327666932816004932Corynebacterium glutamicum ATCC 13032, complete genomeputative helicase9e-1165.5
NC_006958:3240019:3249976324997632549164941Corynebacterium glutamicum ATCC 13032, complete genomeDNA or RNA helicase of superfamily II9e-1165.9
NC_008538:46469:5781957819626604842Arthrobacter sp. FB24 plasmid 2, complete sequencetype III restriction enzyme, res subunit3e-1063.9
NC_017955:1667500:1678714167871416834834770Modestobacter marinus, complete genomeHelicase8e-1062.4
NC_016943:1442885:1462107146210714668704764Blastococcus saxobsidens DD2, complete genomeputative Helicase1e-0962
NC_015673:1038673:1053210105321010548981689Corynebacterium resistens DSM 45100 chromosome, complete genomehypothetical protein1e-0962
NC_014168:1724993:1735931173593117408414911Segniliparus rotundus DSM 44985 chromosome, complete genometype III restriction protein res subunit4e-0960.1
NC_010545:1475410:148354014835401483938399Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein1e-0858.5
NC_017167:2298962:232698323269832327630648Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1putative helicase8e-0855.8
NC_017167:1648913:171959117195911719857267Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1putative helicase5e-0753.1
NC_008826:84218:8994089940947874848Methylibium petroleiphilum PM1 plasmid RPME01, complete sequenceadenine specific DNA methyltransferase, putative7e-0752.8
NC_013165:1584977:1608043160804316135865544Slackia heliotrinireducens DSM 20476, complete genomepredicted helicase9e-0752.4