Pre_GI: BLASTP Hits

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Query: NC_010161:1179000:1194186 Bartonella tribocorum CIP 105476, complete genome

Start: 1194186, End: 1195058, Length: 873

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014923:5721686:572571057257105726384675Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completeDSBA oxidoreductase7e-26117
NC_019973:5650646:565467056546705655344675Mesorhizobium australicum WSM2073, complete genomeprotein-disulfide isomerase7e-26117
NC_015675:6276357:628038162803816281055675Mesorhizobium opportunistum WSM2075 chromosome, complete genomeDSBA oxidoreductase7e-26117
NC_009832:3703202:370520637052063705922717Serratia proteamaculans 568, complete genomeDSBA oxidoreductase9e-21100
NC_007797:107950:129926129926130672747Anaplasma phagocytophilum HZ, complete genomethiol:disulfide oxidoreductase1e-20100
NC_007799:257500:278286278286279026741Ehrlichia chaffeensis str. Arkansas, complete genomedisulfide oxidoreductase9e-2097.8
NC_009007:57804:727517275173572822Rhodobacter sphaeroides 2.4.1 plasmid A, partial sequenceDSBA oxidoreductase8e-1891.3
NC_013009:809681:821764821764822609846Neorickettsia risticii str. Illinois, complete genomedisulfide oxidoreductase1e-1687
NC_017082:6687020:668702066870206687652633Bradyrhizobium sp. S23321, complete genomehypothetical protein2e-1686.3
NC_007712:1262593:128735212873521288077726Sodalis glossinidius str. 'morsitans', complete genomesuppressor for copper-sensitivity C5e-1582
NC_012808:1220378:126429412642941264929636Methylobacterium extorquens AM1, complete genomeputative thioredoxin domain protein precursor7e-1478.2
NC_012988:670101:688645688645689280636Methylobacterium extorquens DM4, complete genomethioredoxin domain-containing protein1e-1377.4
NC_009378:106193:112951112951113742792Yersinia pestis Pestoides F plasmid MT, complete sequencehypothetical protein7e-1374.7
NC_006625:63342:720817208173037957Klebsiella pneumoniae NTUH-K2044 plasmid pK2044, complete sequencehypothetical protein1e-1273.9
NC_012988:670101:696636696636697358723Methylobacterium extorquens DM4, complete genomehypothetical protein5e-1271.6
NC_021066:3703725:371839237183923719183792Raoultella ornithinolytica B6, complete genomehypothetical protein1e-1067.4
NC_010067:2881448:289534428953442896189846Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein7e-1064.7
NC_011149:25760:312763127632121846Salmonella enterica subsp. enterica serovar Agona str. SL483,1e-0860.5
NC_016810:25803:312743127432119846Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-0860.1
NC_011294:25569:310393103931884846Salmonella enterica subsp. enterica serovar Enteritidis strhypothetical protein2e-0860.1
NC_011274:25692:311623116232007846Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91hypothetical protein2e-0860.1
NC_011205:25805:312753127532120846Salmonella enterica subsp. enterica serovar Dublin str. CT_020218532e-0860.1
NC_003197:25803:312743127432119846Salmonella typhimurium LT2, complete genomeputative thiol-disulfide isomerase2e-0860.1
NC_016831:25760:312753127532120846Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein2e-0860.1
NC_016856:25803:312743127432119846Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative thiol-disulfide isomerase2e-0860.1
NC_010102:25893:313623136232207846Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein2e-0860.1
NC_017046:25758:312743127432119846Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein2e-0860.1
NC_016863:25804:312753127532120846Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative thiol-disulfide isomerase2e-0860.1
NC_016860:25758:312743127432119846Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-0860.1
NC_016857:25803:312743127432119846Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative thiol-disulfide isomerase2e-0860.1
NC_011094:25762:312783127832123846Salmonella enterica subsp. enterica serovar Schwarzengrund strhypothetical protein2e-0859.7
NC_016609:2730449:273831027383102738840531Niastella koreensis GR20-10 chromosome, complete genomeDSBA oxidoreductase3e-0859.7
NC_007333:1743890:175499717549971755836840Thermobifida fusca YX, complete genomesimilar to Protein-disulfide isomerase5e-0858.5
NC_009342:135500:155671155671156354684Corynebacterium glutamicum R chromosome, complete genomehypothetical protein8e-0857.8
NC_014623:464324:470970470970471626657Stigmatella aurantiaca DW4/3-1 chromosome, complete genomeDSBA oxidoreductase family protein6e-0755.1
NC_016614:822715:831168831168831941774Vibrio sp. EJY3 chromosome 2, complete sequencehypothetical protein7e-0754.7
NC_013849:466091:498097498097499047951Ferroglobus placidus DSM 10642 chromosome, complete genomeDSBA oxidoreductase1e-0653.9
NC_004631:25807:312783127832123846Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein2e-0653.5
NC_006511:25796:312673126732112846Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein2e-0653.5
NC_003198:25807:312783127832123846Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein2e-0653.5
NC_011147:25836:313073130732152846Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein2e-0653.5
NC_016832:25807:312783127832123846Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein2e-0653.5
NC_011080:25751:312673126732112846Salmonella enterica subsp. enterica serovar Newport str. SL254,BcfH2e-0653.5
NC_009434:695582:762105762105762710606Pseudomonas stutzeri A1501, complete genomeouter membrane protein3e-0652.8
NC_009092:1874888:188535218853521886140789Shewanella loihica PV-4, complete genomeDSBA oxidoreductase4e-0652.4