Pre_GI: BLASTP Hits

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Query: NC_010161:1179000:1193435 Bartonella tribocorum CIP 105476, complete genome

Start: 1193435, End: 1193932, Length: 498

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017262:623351:643202643202643684483Zymomonas mobilis subsp. mobilis ATCC 10988 chromosome, completeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-26118
NC_014774:1120383:115047411504741150971498Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completeacetyl-CoA carboxylase biotin carboxyl carrier protein subunit9e-25112
NC_006677:435652:461151461151461597447Gluconobacter oxydans 621H, complete genomeBiotin carboxyl carrier protein of acetyl-CoA carboxylase4e-23107
NC_011753:3088952:310321831032183103670453Vibrio splendidus LGP32 chromosome 1, complete genomeputative biotin carboxyl carrier protein6e-23106
NC_007963:2555012:257289025728902573354465Chromohalobacter salexigens DSM 3043, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-22105
NC_007712:254000:272835272835273269435Sodalis glossinidius str. 'morsitans', complete genomebiotin carboxyl carrier protein3e-22104
NC_016893:135845:149419149419149883465Wigglesworthia glossinidia endosymbiont of Glossina morsitansacetyl CoA carboxylase, BCCP subunit1e-21102
NC_011312:3060371:307445030744503074905456Aliivibrio salmonicida LFI1238 chromosome chromosome 1, completeacetyl-CoA carboxylase biotin carboxyl carrier protein subunit3e-21100
NC_014541:475350:520297520297520749453Ferrimonas balearica DSM 9799 chromosome, complete genomebiotin carboxyl carrier protein6e-2199.8
NC_016012:805680:814648814648815133486Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-2099
NC_004344:672550:678993678993679451459Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein1e-1892.4
NC_013192:171000:174174174174174665492Leptotrichia buccalis DSM 1135, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1890.5
NC_013939:420500:437876437876438358483Deferribacter desulfuricans SSM1, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein5e-1890.5
NC_015557:278000:290635290635291081447Hydrogenobaculum sp. 3684 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1890.5
NC_015587:278000:290671290671291117447Hydrogenobaculum sp. SHO chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1890.5
NC_020411:278000:290667290667291113447Hydrogenobaculum sp. HO, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1890.5
NC_009483:2086021:211536821153682115841474Geobacter uraniireducens Rf4 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1890.1
NC_015499:119200:128829128829129293465Thermodesulfobium narugense DSM 14796 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1787.4
NC_014393:4988127:499625749962574996757501Clostridium cellulovorans 743B chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1787.4
NC_014935:1955226:197391719739171974387471Nitratifractor saLSUginis DSM 16511 chromosome, complete genomebiotin carboxyl carrier protein4e-1787.4
NC_008095:7139056:714388671438867144485600Myxococcus xanthus DK 1622, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1787.4
NC_015672:1921023:194716019471601947624465Flexistipes sinusarabici DSM 4947 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1787
NC_015425:34861:470064700647485480Clostridium botulinum BKT015925 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1787
NC_011661:1049767:105741910574191057862444Dictyoglomus turgidum DSM 6724, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1787
NC_013204:2955500:2974093297409329759821890Eggerthella lenta DSM 2243, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein6e-1786.7
NC_020291:1266885:129514412951441295659516Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomebiotin carboxyl carrier protein of acetyl-CoA carboxylase AccB8e-1786.3
NC_015711:8909256:891411089141108914709600Myxococcus fulvus HW-1 chromosome, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein1e-1685.9
NC_009617:1278000:128634312863431286858516Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1684.7
NC_015144:1526669:153375315337531534229477Weeksella virosa DSM 16922 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1684
NC_007498:2475781:247972724797272480203477Pelobacter carbinolicus DSM 2380, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1683.6
NC_004557:81362:915809158092038459Clostridium tetani E88, complete genomebiotin carboxyl carrier protein of acetyl-coA carboxylase6e-1683.2
NC_013798:345339:371309371309371797489Streptococcus gallolyticus UCN34, complete genomeacetyl-CoA carboxylase (biotin carboxyl carrier subunit)7e-1683.2
NC_016510:1874942:188209618820961882590495Flavobacterium columnare ATCC 49512 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrierprotein8e-1682.8
NC_011979:3341099:334109933410993341566468Geobacter sp. FRC-32, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein8e-1682.8
NC_015738:629297:6453906453906472821893Eggerthella sp. YY7918, complete genomehypothetical protein1e-1582
NC_015277:6213304:918291829667486Sphingobacterium sp. 21 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein2e-1582
NC_015275:3299923:330784733078473308308462Clostridium lentocellum DSM 5427 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1581.3
NC_013928:395028:420954420954421442489Streptococcus mutans NN2025, complete genomebiotin carboxyl carrier protein of acetyl-CoA carboxylase3e-1580.9
NC_010674:1170264:118044411804441180938495Clostridium botulinum B str. Eklund 17B, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1580.5
NC_017295:3762622:377202437720243772503480Clostridium acetobutylicum EA 2018 chromosome, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein2e-1478.6
NC_015687:3766000:377425537742553774734480Clostridium acetobutylicum DSM 1731 chromosome, complete genomebiotin carboxyl carrier protein of acetyl-CoA carboxylase2e-1478.6
NC_003030:3763054:377267237726723773151480Clostridium acetobutylicum ATCC 824, complete genomeBiotin carboxyl carrier protein of acetyl-CoA carboxylase2e-1478.6
NC_008593:37456:477024770248190489Clostridium novyi NT, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein2e-1478.6
NC_010571:2041277:204956020495602050018459Opitutus terrae PB90-1, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1477.4
NC_015391:1323171:133354913335491334037489Carnobacterium sp. 17-4 chromosome, complete genomebiotin carboxyl carrier protein of acetyl-CoA carboxylase8e-1476.3
NC_010001:649000:660000660000660431432Clostridium phytofermentans ISDg, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein8e-1476.3
NC_012778:1778654:179470417947041795156453Eubacterium eligens ATCC 27750, complete genomeoxaloacetate decarboxylase1e-1375.5
NC_014328:4546390:455466945546694555181513Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative biotin carboxyl carrier protein3e-1374.7
NC_011894:957897:975779975779976204426Methylobacterium nodulans ORS 2060, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1374.3
NC_013720:5769910:584463458446345845143510Pirellula staleyi DSM 6068, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein4e-1373.9
NC_014219:2491021:249676224967622497265504Bacillus selenitireducens MLS10 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1373.6
NC_010516:3903867:391296139129613913437477Clostridium botulinum B1 str. Okra, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein6e-1373.6
NC_010520:3938490:394759639475963948072477Clostridium botulinum A3 str. Loch Maree, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein8e-1373.2
NC_021182:4882494:489033748903374890831495Clostridium pasteurianum BC1, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-1272.4
NC_016938:1492486:149832014983201498835516Melissococcus plutonius DAT561 chromosome 1, complete genomebiotin carboxyl carrier protein of acetyl-CoA carboxylase1e-1272.4
NC_009495:3832500:384160238416023842078477Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein1e-1272.4
NC_009697:3809044:381813638181363818612477Clostridium botulinum A str. ATCC 19397 chromosome, completeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-1272.4
NC_009698:3706154:371524637152463715722477Clostridium botulinum A str. Hall chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein1e-1272.4
NC_017297:3939328:394842339484233948899477Clostridium botulinum F str. 230613 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein2e-1271.6
NC_009699:3940984:395008039500803950556477Clostridium botulinum F str. Langeland chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein2e-1271.6
NC_012563:4101000:411012041101204110596477Clostridium botulinum A2 str. Kyoto, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1270.5
NC_010723:1133163:114434111443411144835495Clostridium botulinum E3 str. Alaska E43, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-1270.5
NC_012658:3923546:393265539326553933131477Clostridium botulinum Ba4 str. 657 chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein2e-1168.6
NC_013209:2248119:224992222499222250371450Acetobacter pasteurianus IFO 3283-01, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein2e-1168.6
NC_017111:2248096:224989922498992250348450Acetobacter pasteurianus IFO 3283-32, complete genomeacetyl-CoA carboxylase biotin carboxyl carrier protein2e-1168.6
NC_014310:785220:786251786251786709459Ralstonia solanacearum PSI07 megaplasmid, complete sequencebiotin carboxyl carrier protein of acetyl-CoA carboxylase (bccp)2e-1168.6
NC_012792:1091669:111160611116061112046441Variovorax paradoxus S110 chromosome 2, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein3e-1167.8
NC_018528:1932000:194786319478631948333471Lactobacillus helveticus R0052 chromosome, complete genomeacetyl-CoA biotin carboxyl carrier1e-1065.9
NC_015602:1949610:195427119542711954741471Lactobacillus kefiranofaciens ZW3 chromosome, complete genomeacetyl-CoA biotin carboxyl carrier1e-1065.9
NC_010080:1885677:189915518991551899625471Lactobacillus helveticus DPC 4571, complete genomeAcetyl-CoA biotin carboxyl carrier1e-1065.5
NC_019942:987134:105792110579211058301381Aciduliprofundum sp. MAR08-339, complete genomeacetyl/propionyl-CoA carboxylase, alpha subunit6e-1063.5
NC_006677:215466:230450230450230893444Gluconobacter oxydans 621H, complete genomeBiotin carboxyl carrier protein of acetyl-CoA carboxylase3e-0961.2
NC_014910:1050706:106738310673831067856474Alicycliphilus denitrificans BC chromosome, complete genomeacetyl-CoA carboxylase, biotin carboxyl carrier protein5e-0960.5
NC_007760:535825:5477025477025506802979Anaeromyxobacter dehalogenans 2CP-C, complete genomeBiotin carboxylase1e-0859.3
NC_000868:834872:853742853742854179438Pyrococcus abyssi GE5, complete genomemethylmalonyl-CoA decarboxylase gamma chain2e-0858.5
NC_015437:572788:576562576562576948387Selenomonas sputigena ATCC 35185 chromosome, complete genomebiotin/lipoyl attachment domain-containing protein2e-0755.1
NC_009718:1411793:142557614255761426019444Fervidobacterium nodosum Rt17-B1, complete genomebiotin/lipoyl attachment domain-containing protein2e-0755.1
NC_009617:3184924:320648632064863206947462Clostridium beijerinckii NCIMB 8052 chromosome, complete genomebiotin/lipoyl attachment domain-containing protein3e-0754.3
NC_012660:2143376:216734421673442167589246Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein4e-0753.9
NC_011894:957897:979272979272979673402Methylobacterium nodulans ORS 2060, complete genomebiotin/lipoyl attachment domain-containing protein5e-0753.9
NC_019968:8397:269352693527366432Prevotella dentalis DSM 3688 chromosome 2, complete sequenceacetyl/propionyl-CoA carboxylase, alpha subunit5e-0753.5
NC_014323:4665610:471198047119804712228249Herbaspirillum seropedicae SmR1 chromosome, complete genomebiotin carboxyl carrier protein8e-0753.1
NC_015555:277364:284799284799285179381Thermoanaerobacterium xylanolyticum LX-11 chromosome, completebiotin/lipoyl attachment domain-containing protein2e-0652
NC_007333:1743890:174525317452531745615363Thermobifida fusca YX, complete genomehypothetical protein2e-0652
NC_011768:3854455:3870119387011938720471929Desulfatibacillum alkenivorans AK-01, complete genomeOxaloacetate decarboxylase3e-0651.2
NC_015164:3431279:345416534541653454593429Bacteroides salanitronis DSM 18170 chromosome, complete genomebiotin/lipoyl attachment domain-containing protein6e-0650.1
NC_011283:4767269:4767269476726947690381770Klebsiella pneumoniae 342 chromosome, complete genomeoxaloacetate decarboxylase7e-0650.1