Pre_GI: BLASTP Hits

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Query: NC_010161:1179000:1184375 Bartonella tribocorum CIP 105476, complete genome

Start: 1184375, End: 1185274, Length: 900

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010161:2235500:2245926224592622469391014Bartonella tribocorum CIP 105476, complete genomehypothetical protein3e-169594
NC_012846:986877:1013486101348610144991014Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein7e-149526
NC_012846:986877:1012476101247610134771002Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein2e-86319
NC_010161:1179000:1183252118325211842531002Bartonella tribocorum CIP 105476, complete genomehypothetical protein8e-84310
NC_010161:2235500:2246948224694822479491002Bartonella tribocorum CIP 105476, complete genomehypothetical protein2e-83309
NC_010161:1179000:1185282118528211864121131Bartonella tribocorum CIP 105476, complete genomephage related protein3e-64245
NC_012846:986877:1014507101450710156341128Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein6e-64244
NC_010161:2235500:2244788224478822459181131Bartonella tribocorum CIP 105476, complete genomehypothetical protein3e-63241
NC_012846:1147000:115621211562121157192981Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein1e-60233
NC_008783:222000:237453237453238424972Bartonella bacilliformis KC583, complete genomehypothetical protein4e-57221
NC_005956:1019788:102551310255131026493981Bartonella henselae str. Houston-1, complete genomePhage related protein2e-55216
NC_008781:3508784:3508784350878435102351452Polaromonas naphthalenivorans CJ2, complete genomephage Tail Collar domain protein3e-1582.8
NC_012808:4098465:4103547410354741048961350Methylobacterium extorquens AM1, complete genomehypothetical protein1e-1480.9
NC_015510:6842692:685581468558146856761948Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeTail Collar domain-containing protein5e-1478.6
NC_016845:1285435:1332909133290913340331125Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,hypothetical protein8e-1271.2
NC_014010:387321:405319405319406185867Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeMicrocystin-dependent protein-like protein8e-0961.2
AC_000091:1191353:121069612106961211232537Escherichia coli W3110 DNA, complete genome1e-0757.4
NC_000913:1188999:120834212083421208878537Escherichia coli K12, complete genomee14 prophage; predicted side tail fiber protein fragment (pseudogene)1e-0757.4
NC_020181:5130513:5173329517332951748041476Enterobacter aerogenes EA1509E, complete genomePhage tail fiber protein4e-0755.8
NC_012962:2587756:2591672259167225926881017Photorhabdus asymbiotica, complete genomesimilar to putative tail fiber protein4e-0755.5
NC_011205:2180598:2193744219374421955821839Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853pilin7e-0755.1
NC_016831:947281:9747529747529765901839Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein7e-0755.1