Pre_GI: BLASTP Hits

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Query: NC_010161:1179000:1183252 Bartonella tribocorum CIP 105476, complete genome

Start: 1183252, End: 1184253, Length: 1002

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010161:2235500:2246948224694822479491002Bartonella tribocorum CIP 105476, complete genomehypothetical protein0637
NC_012846:986877:1012476101247610134771002Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein3e-164577
NC_010161:2235500:2245926224592622469391014Bartonella tribocorum CIP 105476, complete genomehypothetical protein8e-98357
NC_012846:986877:1013486101348610144991014Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein2e-95348
NC_012846:986877:1014507101450710156341128Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein3e-84311
NC_010161:1179000:1185282118528211864121131Bartonella tribocorum CIP 105476, complete genomephage related protein5e-84311
NC_010161:2235500:2244788224478822459181131Bartonella tribocorum CIP 105476, complete genomehypothetical protein1e-81303
NC_010161:1179000:118437511843751185274900Bartonella tribocorum CIP 105476, complete genomephage related protein2e-79296
NC_012846:1147000:115621211562121157192981Bartonella grahamii as4aup, complete genomeputative phage tail fiber protein5e-78291
NC_008783:222000:237453237453238424972Bartonella bacilliformis KC583, complete genomehypothetical protein2e-74279
NC_005956:1019788:102551310255131026493981Bartonella henselae str. Houston-1, complete genomePhage related protein5e-68258
NC_012808:4098465:4103547410354741048961350Methylobacterium extorquens AM1, complete genomehypothetical protein1e-1790.5
NC_015510:6842692:685581468558146856761948Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeTail Collar domain-containing protein2e-1687
NC_008781:3508784:3508784350878435102351452Polaromonas naphthalenivorans CJ2, complete genomephage Tail Collar domain protein6e-1582
NC_008783:222000:237259237259237453195Bartonella bacilliformis KC583, complete genomehypothetical protein1e-1377.4
NC_008783:222000:237065237065237259195Bartonella bacilliformis KC583, complete genomehypothetical protein1e-1377.4
NC_016845:1285435:1332909133290913340331125Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,hypothetical protein4e-1168.9
NC_014010:387321:405319405319406185867Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeMicrocystin-dependent protein-like protein1e-0964.7
NC_010161:1179000:118426211842621184378117Bartonella tribocorum CIP 105476, complete genomehypothetical protein7e-0755.1