Pre_GI: BLASTP Hits

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Query: NC_009974:53865:60738 Herpetosiphon aurantiacus ATCC 23779 plasmid pHAU02, complete

Start: 60738, End: 62609, Length: 1872

Host Lineage: Herpetosiphon aurantiacus; Herpetosiphon; Herpetosiphonaceae; Herpetosiphonales; Chloroflexi; Bacteria

General Information: This strain (ATCC 23779; DSM 785) was isolated from Birch Lake in Minnesota, USA. Herpetosiphon aurantiacus grows in long, flexible, filaments with a transparent section of empty cell wall at the end of the filament. Herpetosiphon spp. and Herpetosiphon-like organisms have been found in soil, freshwater, and sewage treatment plants. These organisms have been implicated in the bulking of sludge in sewage treatment plants, which is problematic in that the sludge retains more water, making subsequent disposal difficult.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009523:907775:9113949113949135712178Roseiflexus sp. RS-1 chromosome, complete genomeN-6 DNA methylase6e-62239
NC_015125:1668780:1679326167932616808101485Microbacterium testaceum StLB037, complete genometype I restriction-modification system methyltransferase subunit4e-24113
NC_015945:1908895:1918150191815019197871638Muricauda ruestringensis DSM 13258 chromosome, complete genomeN-6 DNA methylase1e-23112
NC_015737:449914:4624014624014639031503Clostridium sp. SY8519, complete genomehypothetical protein2e-23110
NC_010831:173499:1827671827671850942328Chlorobium phaeobacteroides BS1, complete genomeN-6 DNA methylase2e-23110
NC_017068:2055500:2068586206858620700491464Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative type I restriction-modification system M subunit4e-23110
NC_009338:817854:8296638296638311171455Mycobacterium gilvum PYR-GCK chromosome, complete genomeN-6 DNA methylase6e-23109
NC_014643:2056280:2065628206562820671361509Rothia dentocariosa ATCC 17931 chromosome, complete genometype I restriction-modification system DNA-methyltransferase9e-23108
NC_019897:3613830:3632763363276336342321470Thermobacillus composti KWC4 chromosome, complete genometype I restriction-modification system methyltransferase subunit3e-22107
NC_015216:1102837:1116772111677211182891518Methanobacterium sp. AL-21 chromosome, complete genomeN-6 DNA methylase3e-22107
NC_013406:1217385:1236200123620012376691470Paenibacillus sp. Y412MC10 chromosome, complete genomeN-6 DNA methylase2e-22107
NC_014815:6616500:6658578665857866612742697Micromonospora sp. L5 chromosome, complete genomen-6 DNA methylase5e-22106
NC_013959:1059004:1067359106735910698062448Sideroxydans lithotrophicus ES-1 chromosome, complete genomerestriction modification system DNA specificity domain protein1e-21105
NC_009051:1074993:1082632108263210841491518Methanoculleus marisnigri JR1, complete genomeN-6 DNA methylase2e-21104
NC_008346:584305:6055326055326070011470Syntrophomonas wolfei subsp. wolfei str. Goettingen, completetype I restriction modification system M subunit (site-specific DNA-methyltransferase subunit)1e-20102
NC_014640:6815264:6825592682559268270701479Achromobacter xylosoxidans A8 chromosome, complete genomeN-6 adenine-specific DNA methylase 31e-20101
NC_018876:2189798:2216770221677022182841515Methanolobus psychrophilus R15 chromosome, complete genomeN-6 DNA methylase3e-20100
NC_016593:416661:4210304210304224871458Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completeN-6 DNA methylase3e-20100
NC_014934:244587:2429322429322445901659Cellulophaga algicola DSM 14237 chromosome, complete genomen-6 DNA methylase3e-20100
NC_014206:411143:4160804160804175341455Geobacillus sp. C56-T3 chromosome, complete genomeN-6 DNA methylase3e-20100
NC_015259:734795:7477337477337492711539Polymorphum gilvum SL003B-26A1 chromosome, complete genomeType I restriction modification system M subunit (Site-specific DNA-methyltransferase subunit)2e-20100
NC_006510:372826:3771953771953786491455Geobacillus kaustophilus HTA426, complete genometype I restriction modification system M subunit (site-specific DNA-methyltransferase subunit)2e-20100
NC_020211:554736:5732915732915749251635Serratia marcescens WW4, complete genomeDNA methyltransferase M5e-2099.8
NC_007908:1108494:1126795112679511283451551Rhodoferax ferrireducens T118, complete genomeN-6 DNA methylase6e-2099.8
NC_016612:2009927:2034086203408620357201635Klebsiella oxytoca KCTC 1686 chromosome, complete genomeN-6 DNA methylase6e-2099.4
NC_008577:2402165:2424267242426724258081542Shewanella sp. ANA-3 chromosome 1, complete sequenceN-6 DNA methylase1e-1998.6
CP002516:4236680:4249640424964042512741635Escherichia coli KO11, complete genomeN-6 DNA methylase2e-1998.2
CP002185:4750571:4761595476159547632291635Escherichia coli W, complete genomeN-6 DNA methylase2e-1998.2
NC_016902:4236680:4249640424964042512741635Escherichia coli KO11FL chromosome, complete genomeN-6 DNA methylase2e-1998.2
NC_011083:4547825:4596636459663645982701635Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,N-6 DNA methylase2e-1998.2
NC_010337:616304:6275536275536289891437Heliobacterium modesticaldum Ice1, complete genometype i restriction-modification system, m subunit2e-1997.8
NC_009925:647752:6654316654316665761146Acaryochloris marina MBIC11017, complete genometype I restriction modification system M subunit, putative2e-1997.8
NC_011745:2209288:2219872221987222215451674Escherichia coli ED1a chromosome, complete genomeputative HsdM; type I restriction modification enzyme methylase subunit2e-1997.8
NC_011071:1178423:1188134118813411897171584Stenotrophomonas maltophilia R551-3, complete genomeN-6 DNA methylase2e-1997.8
NC_015578:3495034:3499205349920535006711467Treponema primitia ZAS-2 chromosome, complete genometype I restriction modification system M subunit2e-1997.4
NC_016803:1646342:1661363166136316630271665Desulfovibrio desulfuricans ND132 chromosome, complete genomeN-6 DNA methylase3e-1997.4
NC_012962:4591295:4594771459477145964051635Photorhabdus asymbiotica, complete genometype I restriction enzyme, modification subunit3e-1997.4
NC_010814:1441327:1460313146031314617461434Geobacter lovleyi SZ, complete genomeN-6 DNA methylase7e-1996.3
NC_012917:3241196:3253591325359132552251635Pectobacterium carotovorum subsp. carotovorum PC1, complete genomeN-6 DNA methylase8e-1995.9
NC_016887:3286436:3327582332758233291141533Nocardia cyriacigeorgica GUH-2, complete genomerestriction-modification system methyltransferase1e-1895.1
NC_016047:2480921:2492305249230524951812877Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completetype I restriction-modification system, M subunit2e-1894.4
NC_008312:3728329:3732458373245837339391482Trichodesmium erythraeum IMS101, complete genomeN-6 DNA methylase2e-1894.4
NS_000195:526983:5454715454715479842514Candidatus Cloacamonas acidaminovoransRestriction modification system DNA specificity domain:N-6 DNA methylase:Type I restriction-modification system, M subunit3e-1894.4
NC_006361:2920028:2924075292407529256191545Nocardia farcinica IFM 10152, complete genomeputative restriction-modification system methyltransferase4e-1894
NC_009943:1499111:1503056150305615045281473Candidatus Desulfococcus oleovorans Hxd3, complete genomeN-6 DNA methylase1e-1792
NC_016027:1902854:1924814192481419262711458Gluconacetobacter xylinus NBRC 3288, complete genometype I DNA methyltransferase M subunit1e-1792
NC_013203:202008:2381562381562396761521Atopobium parvulum DSM 20469, complete genomeN-6 DNA methylase1e-1792
NC_007645:5160133:5183614518361451852331620Hahella chejuensis KCTC 2396, complete genomeType I restriction-modification system methyltransferase subunit2e-1791.3
NC_006361:2225072:2238437223843722413372901Nocardia farcinica IFM 10152, complete genomeputative restriction-modification system endonuclease/methyltransferase3e-1790.9
NC_014727:368698:3784043784043798791476Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,type i site-specific deoxyribonuclease methyltransferase subunit3e-1790.5
NC_015953:3227000:3237201323720132387241524Streptomyces sp. SirexAA-E chromosome, complete genomeN-6 DNA methylase5e-1789.7
NC_012691:1250385:1254862125486212564031542Tolumonas auensis DSM 9187, complete genomeN-6 DNA methylase6e-1789.7
NC_009720:870194:8778328778328799642133Xanthobacter autotrophicus Py2, complete genomeN-6 DNA methylase7e-1789.4
NC_008595:5168941:5178332517833251798191488Mycobacterium avium 104, complete genometype I restriction-modification system, M subunit8e-1789.4
NC_014306:4376012:4401437440143744029091473Erwinia billingiae Eb661, complete genomeType I restriction enzyme EcoEI M protein8e-1789.4
NC_016745:1548426:1558216155821615597271512Oceanimonas sp. GK1 chromosome, complete genomeType I restriction enzyme EcoEI M protein (M.EcoEI)1e-1689
NC_005139:2201820:2208750220875022106661917Vibrio vulnificus YJ016 chromosome I, complete sequencetype I restriction-modification system methyltransferase subunit1e-1689
NC_010170:4196197:4213471421347142149491479Bordetella petrii, complete genometype I restriction modification enzyme M subunit1e-1688.6
NC_015500:2866027:2880132288013228816611530Treponema brennaborense DSM 12168 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)2e-1688.2
NC_017986:1885613:1910114191011419115831470Pseudomonas putida ND6 chromosome, complete genomeN-6 DNA methylase2e-1687.8
NC_013720:5769910:5788430578843057900941665Pirellula staleyi DSM 6068, complete genomeN-6 DNA methylase2e-1687.8
NC_008358:2638245:2694637269463726961781542Hyphomonas neptunium ATCC 15444, complete genometype I restriction-modification system, M subunit2e-1687.8
NC_011144:1073944:1087216108721610886731458Phenylobacterium zucineum HLK1, complete genometype I restriction-modification system, M subunit3e-1687.4
NC_009656:6224221:6243211624321162446801470Pseudomonas aeruginosa PA7 chromosome, complete genometype I restriction-modification system subunit M4e-1687
NC_011138:3881446:3900070390007039017161647Alteromonas macleodii 'Deep ecotype', complete genomeType I restriction-modification system methyltransferase subunit4e-1687
NC_011149:4677412:4698715469871547002141500Salmonella enterica subsp. enterica serovar Agona str. SL483,N-6 DNA methylase4e-1687
NC_004603:370320:3892453892453907351491Vibrio parahaemolyticus RIMD 2210633 chromosome I, completetype I restriction enzyme M protein7e-1686.3
NC_015633:2801321:2801321280132128025831263Vibrio anguillarum 775 chromosome chromosome I, complete sequencetype I restriction-modification system methylation8e-1685.9
NC_010995:764567:7750317750317765031473Cellvibrio japonicus Ueda107, complete genometype I restriction-modification system, M subunit1e-1585.5
NC_002947:5386489:5395521539552153969901470Pseudomonas putida KT2440, complete genometype I restriction-modification system, M subunit1e-1585.5
NC_014965:997344:1008092100809210095821491Vibrio vulnificus MO6-24/O chromosome I, complete sequencetype I restriction-modification system DNA-methyltransferase subunit M1e-1585.5
NC_021177:3627947:3639424363942436410011578Streptomyces fulvissimus DSM 40593, complete genomeType I restriction-modification system methylation subunit3e-1584
NC_008346:2579756:2601586260158626042612676Syntrophomonas wolfei subsp. wolfei str. Goettingen, completetype I restriction-modification system, M subunit3e-1584
NC_010682:1:6281628184132133Ralstonia pickettii 12J chromosome 1, complete sequenceN-6 DNA methylase3e-1584
NC_009943:940835:9527629527629542431482Candidatus Desulfococcus oleovorans Hxd3, complete genomeN-6 DNA methylase4e-1584
NC_018868:1352000:1369108136910813706071500Simiduia agarivorans SA1 = DSM 21679 chromosome, complete genomeN-6 DNA methylase4e-1583.6
NC_013730:3729626:3745507374550737470151509Spirosoma linguale DSM 74, complete genomeSite-specific DNA-methyltransferase (adenine- specific)4e-1583.6
NC_010003:1126800:1143739114373911461862448Petrotoga mobilis SJ95, complete genometype I restriction-modification system, M subunit4e-1583.6
NC_005139:2201820:2219064221906422205631500Vibrio vulnificus YJ016 chromosome I, complete sequencetype I restriction-modification system methyltransferase subunit5e-1583.2
NC_014216:3003347:3004572300457230060681497Desulfurivibrio alkaliphilus AHT2 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)5e-1583.2
NC_015565:2408669:2415342241534224169101569Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completetype I restriction-modification system, M subunit9e-1582.4
NC_014034:1418681:1424302142430214257471446Rhodobacter capsulatus SB1003 chromosome, complete genometype I restriction-modification system RcaSBIIIP subunit M2e-1481.3
NC_013967:2103968:2128977212897721303711395Haloferax volcanii DS2 chromosome, complete genometype I restriction-modification system methylation subunit2e-1481.3
NC_012778:1573847:1590229159022915929072679Eubacterium eligens ATCC 27750, complete genometype I restriction enzyme M protein2e-1480.9
NC_016023:1923170:1930663193066319321921530Bacillus coagulans 36D1 chromosome, complete genometype I restriction-modification system, M subunit3e-1480.9
NC_016023:267581:2782982782982798271530Bacillus coagulans 36D1 chromosome, complete genometype I restriction-modification system, M subunit3e-1480.9
NC_015587:90539:9389993899963372439Hydrogenobaculum sp. SHO chromosome, complete genometype I restriction-modification system, M subunit4e-1480.5
NC_020411:90538:9389893898963362439Hydrogenobaculum sp. HO, complete genometype I restriction-modification system, M subunit4e-1480.5
NC_015557:90503:9386393863963012439Hydrogenobaculum sp. 3684 chromosome, complete genometype I restriction-modification system, M subunit4e-1480.5
NC_007777:4796627:4799751479975148022012451Frankia sp. CcI3, complete genomeN-6 DNA methylase6e-1479.7
NC_008782:2781229:2785296278529627867741479Acidovorax sp. JS42, complete genomeN-6 DNA methylase6e-1479.7
NC_007519:3391090:3392825339282533943421518Desulfovibrio alaskensis G20 chromosome, complete genometype I restriction-modification system, M subunit7e-1479.3
NC_015437:767572:7775257775257791021578Selenomonas sputigena ATCC 35185 chromosome, complete genometype I restriction-modification system, M subunit9e-1479.3
NC_020054:4161049:4179579417957941811561578Fibrella aestuarina BUZ 2 drat genometype I restriction enzyme M protein1e-1379
NC_008278:5399715:5415745541574554181652421Frankia alni ACN14a, complete genomeRestriction enzyme subunit M (methylation)1e-1378.6
NC_014002:1061501:1069634106963410711331500Methanohalophilus mahii DSM 5219 chromosome, complete genomeN-6 DNA methylase2e-1378.2
NC_009429:401500:4225464225464239911446Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, completeEcoEI R domain-containing protein2e-1378.2
NC_011979:3112911:3125675312567531281312457Geobacter sp. FRC-32, complete genomeN-6 DNA methylase2e-1378.2
NC_020541:2551539:2560528256052825620061479Rhodanobacter sp. 2APBS1, complete genometype I restriction-modification system methyltransferase subunit3e-1377.4
NC_014098:3008951:3028152302815230296601509Bacillus tusciae DSM 2912 chromosome, complete genomeN-6 DNA methylase3e-1377.4
NC_009076:75535:8877788777912452469Burkholderia pseudomallei 1106a chromosome I, complete sequencetype I restriction-modification system M subunit4e-1377
NC_009715:1470419:1485297148529714867661470Campylobacter curvus 525.92 chromosome, complete genomeSec-independent protein translocase protein TatC4e-1377
NC_005090:1082213:1093975109397510955371563Wolinella succinogenes DSM 1740, complete genomeTYPE I SITE-SPECIFIC DEOXYRIBONUCLEASE4e-1377
NC_013235:5127148:5144962514496251473942433Nakamurella multipartita DSM 44233, complete genometype I restriction-modification system, M subunit4e-1377
NC_013720:1382561:1395258139525813977652508Pirellula staleyi DSM 6068, complete genometype I restriction-modification system, M subunit5e-1376.6
NC_004463:5540924:5559153555915355617922640Bradyrhizobium japonicum USDA 110, complete genometype I restriction-modification system specificity subunit7e-1376.3
NC_015571:2002489:2039640203964020411481509Porphyromonas gingivalis TDC60, complete genometype I restriction-modification system, subunit M7e-1376.3
NC_015977:255029:2619492619492635141566Roseburia hominis A2-183 chromosome, complete genometype I restriction-modification system subunit M7e-1376.3
NC_016943:4799915:4806012480601248075141503Blastococcus saxobsidens DD2, complete genomeadenine-specific DNA-methyltransferase6e-1376.3
NC_014655:130636:1430591430591444861428Leadbetterella byssophila DSM 17132 chromosome, complete genomesite-specific DNA-methyltransferase (adenine-specific)6e-1376.3
NC_012440:1215838:1231017123101712337132697Persephonella marina EX-H1, complete genometype I restriction enzyme M protein (HsdM)6e-1376.3
NC_014394:3114648:3130848313084831323231476Gallionella capsiferriformans ES-2 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)9e-1375.9
NC_018876:587094:6072826072826087961515Methanolobus psychrophilus R15 chromosome, complete genometype I restriction-modification system, M subunit2e-1275.1
NC_014365:2810405:2836651283665128381681518Desulfarculus baarsii DSM 2075 chromosome, complete genometype I restriction-modification system, M subunit2e-1275.1
NC_009925:2240871:2244716224471622461761461Acaryochloris marina MBIC11017, complete genometype I restriction-modification system, M subunit1e-1275.1
NC_016002:2946702:297210929721092972951843Pseudogulbenkiania sp. NH8B, complete genometype I restriction enzyme M protein1e-1275.1
NC_019908:463281:4672814672814688701590Brachyspira pilosicoli P43/6/78 chromosome, complete genometype-I restriction-modification system HsdM2e-1274.7
NC_008699:1132790:1166348116634811679071560Nocardioides sp. JS614, complete genometype I restriction-modification system, M subunit2e-1274.7
NC_011294:4604283:4613162461316246144271266Salmonella enterica subsp. enterica serovar Enteritidis strtype I restriction-modification system methyltransferase2e-1274.7
NC_016610:2077603:2092065209206520934861422Tannerella forsythia ATCC 43037 chromosome, complete genomeN-6 DNA methylase2e-1274.7
NC_013440:3813132:3830215383021538321161902Haliangium ochraceum DSM 14365, complete genometype I restriction-modification system, M subunit2e-1274.7
NC_008705:4053070:4060565406056540618541290Mycobacterium sp. KMS, complete genomeN-6 DNA methylase2e-1274.7
NC_008146:4019711:4026083402608340273721290Mycobacterium sp. MCS, complete genomeN-6 DNA methylase2e-1274.7
NC_008782:3800500:3814317381431738158191503Acidovorax sp. JS42, complete genomeN-6 DNA methylase3e-1274.3
NC_010645:558974:5701615701615717201560Bordetella avium 197N, complete genometype i restriction enzyme EcoR124II M protein3e-1274.3
NC_018607:1505908:1519662151966215212511590Brachyspira pilosicoli B2904 chromosome, complete genometype I restriction-modification system, M subunit3e-1274.3
NC_016147:2337244:2351467235146723529901524Pseudoxanthomonas spadix BD-a59 chromosome, complete genomeN-6 DNA methylase2e-1274.3
NC_014215:142500:1590101590101605781569Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,Type I restriction-modification system DNA methylase2e-1274.3
NC_016831:4556761:4565787456578745670401254Salmonella enterica subsp. enterica serovar Gallinarum/pullorumputative Type I restriction-modification system methyltransferase2e-1274.3
NC_014330:169862:1891651891651907541590Brachyspira pilosicoli 95/1000 chromosome, complete genometype-I restriction-modification system HsdM2e-1274.3
NC_008786:2729635:2736727273672727383071581Verminephrobacter eiseniae EF01-2, complete genometype I restriction-modification system, M subunit4e-1273.9
NC_010694:436500:4441294441294456131485Erwinia tasmaniensis, complete genomeType I restriction-modification system, M subunit3e-1273.9
NC_007778:3470661:3485914348591434874611548Rhodopseudomonas palustris HaA2, complete genometype I restriction-modification system, M subunit3e-1273.9
NC_007498:3399478:3420025342002534215391515Pelobacter carbinolicus DSM 2380, complete genometype I restriction-modification system, M subunit3e-1273.9
NC_014217:2760898:2782553278255327840011449Starkeya novella DSM 506 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)4e-1273.6
NC_015167:3469968:3479148347914834806471500Cellulophaga lytica DSM 7489 chromosome, complete genomeN-6 DNA methylase4e-1273.6
NC_014002:1061501:1068153106815310696371485Methanohalophilus mahii DSM 5219 chromosome, complete genometype I restriction-modification system, M subunit6e-1273.2
NC_015865:229883:2436302436302451831554Thermococcus sp. 4557 chromosome, complete genomeType I restriction-modification system DNA-methyltransferase subunit M6e-1273.2
NC_014815:6616500:6672449667244966740171569Micromonospora sp. L5 chromosome, complete genometype i restriction-modification system, m subunit5e-1273.2
NC_006322:741516:7500047500047515961593Bacillus licheniformis ATCC 14580, complete genomehypothetical protein7e-1272.8
NC_006270:741731:7502207502207518121593Bacillus licheniformis ATCC 14580, complete genomeHsdMI7e-1272.8
NC_011899:2165814:2180441218044121818951455Halothermothrix orenii H 168, complete genomeN-6 DNA methylase7e-1272.8
NC_015703:4483500:4499204449920445014052202Runella slithyformis DSM 19594 chromosome, complete genometype I restriction-modification system, M subunit7e-1272.8
NC_013799:1:1776617766202072442Hydrogenobacter thermophilus TK-6, complete genometype I restriction-modification system methyltransferase subunit7e-1272.8
NC_017161:1:1782717827202682442Hydrogenobacter thermophilus TK-6 chromosome, complete genometype I restriction-modification system, M subunit7e-1272.8
NC_009523:907775:9086119086119102151605Roseiflexus sp. RS-1 chromosome, complete genomeN-6 DNA methylase1e-1172.4
NC_004757:2730057:2756159275615927575051347Nitrosomonas europaea ATCC 19718, complete genometype I restriction-modification system methylation subunit9e-1272.4
NC_014314:212579:2180852180852196561572Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completetype I restriction-modification system subunit M9e-1272.4
NC_014618:690056:7117397117397133461608Enterobacter cloacae SCF1 chromosome, complete genometype I restriction-modification system, M subunit1e-1172
NC_015677:1282865:1290551129055112919811431Ramlibacter tataouinensis TTB310 chromosome, complete genometype I site-specific restriction-modification system, M subunit1e-1172
NC_010682:3313944:3332548333254833340441497Ralstonia pickettii 12J chromosome 1, complete sequenceN-6 DNA methylase2e-1171.6
NC_011146:3426500:3463051346305134651742124Geobacter bemidjiensis Bem, complete genomeN-6 DNA methylase2e-1171.6
NC_015144:47783:8532885328868751548Weeksella virosa DSM 16922 chromosome, complete genometype I restriction-modification system, M subunit2e-1171.6
NC_018876:2151226:2164388216438821659651578Methanolobus psychrophilus R15 chromosome, complete genometype I restriction-modification system, M subunit2e-1171.6
NC_007164:1434305:1474878147487814773372460Corynebacterium jeikeium K411, complete genomeputative DNA restriction-modification system, DNA methylase1e-1171.6
NC_016147:2337244:2349280234928023507971518Pseudoxanthomonas spadix BD-a59 chromosome, complete genomeN-6 DNA methylase1e-1171.6
NC_012669:549500:5600985600985616721575Beutenbergia cavernae DSM 12333, complete genometype I restriction-modification system, M subunit1e-1171.6
NC_007575:973559:9819039819039833901488Sulfurimonas denitrificans DSM 1251, complete genomeType I restriction-modification system M subunit2e-1171.2
NC_014550:2562053:2591867259186725943172451Arthrobacter arilaitensis Re117, complete genometype I restriction-modification system modification subunit2e-1171.2
NC_010682:3313944:3330252333025233317631512Ralstonia pickettii 12J chromosome 1, complete sequenceN-6 DNA methylase2e-1171.2
NC_015711:8852850:8863000886300088644391440Myxococcus fulvus HW-1 chromosome, complete genometype I restriction enzyme StySPI M protein3e-1170.9
NC_007681:542494:5628195628195643451527Methanosphaera stadtmanae DSM 3091, complete genomeputative type I restriction-modification system, methyltransferase subunit3e-1170.9
NC_017033:678321:6841296841296856881560Frateuria aurantia DSM 6220 chromosome, complete genometype I restriction system adenine methylase HsdM3e-1170.9
NC_016026:1224129:1232861123286112344501590Micavibrio aeruginosavorus ARL-13 chromosome, complete genometype I restriction-modification system, M subunit3e-1170.9
NC_014814:3892000:3908935390893539113672433Mycobacterium sp. Spyr1 chromosome, complete genometype I restriction-modification system methyltransferase subunit3e-1170.5
NC_010939:321492:3262233262233277761554Actinobacillus pleuropneumoniae serovar 7 str. AP76, completetype I restriction-modification system, M subunit4e-1170.5
NC_014219:192555:2114692114692130641596Bacillus selenitireducens MLS10 chromosome, complete genometype I restriction-modification system, M subunit4e-1170.5
NC_014363:1902868:1914557191455719160411485Olsenella uli DSM 7084 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)5e-1170.1
NC_014655:1396672:1405934140593414074811548Leadbetterella byssophila DSM 17132 chromosome, complete genometype i restrictioN-modification system, m subunit5e-1170.1
NC_008751:1043269:1057445105744510589321488Desulfovibrio vulgaris subsp. vulgaris DP4, complete genomeN-6 DNA methylase5e-1170.1
NC_016051:1005188:1009930100993010115011572Thermococcus sp. AM4 chromosome, complete genomeType I restriction-modification system DNA-methyltransferase subunit M5e-1170.1
NC_007508:570000:5801335801335817491617Xanthomonas campestris pv. vesicatoria str. 85-10, complete genometype I site-specific deoxyribonuclease (modification subunit)4e-1170.1
NC_010278:315941:3212383212383228511614Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,putative type I restriction-modification systemmethyltransferase subunit4e-1170.1
NC_009974:53865:6386563865655801716Herpetosiphon aurantiacus ATCC 23779 plasmid pHAU02, completeN-6 DNA methylase4e-1170.1
NC_015660:3174424:3183546318354631850031458Geobacillus thermoglucosidasius C56-YS93 chromosome, completeadenine-specific DNA-methyltransferase7e-1169.7
NC_007086:557789:5694885694885711041617Xanthomonas campestris pv. campestris str. 8004, complete genometype I site-specific deoxyribonuclease7e-1169.7
NC_015636:288797:2991882991883006901503Methanothermococcus okinawensis IH1 chromosome, complete genomeN-6 DNA methylase7e-1169.7
NC_003902:555699:5673985673985690141617Xanthomonas campestris pv. campestris str. ATCC 33913, completetype I site-specific deoxyribonuclease7e-1169.7
NC_014414:1104386:1121077112107711225911515Parvularcula bermudensis HTCC2503 chromosome, complete genometype I restriction-modification system, M subunit7e-1169.7
NC_004757:2730057:2757998275799827595121515Nitrosomonas europaea ATCC 19718, complete genomepossible type I restriction-modification system methylation subunit6e-1169.7
NC_021184:207492:2050932050932075012409Desulfotomaculum gibsoniae DSM 7213, complete genometype I restriction system adenine methylase HsdM6e-1169.7
NC_008313:1:6960696094672508Ralstonia eutropha H16 chromosome 1, complete sequenceType I restriction-modification system methylation subunit6e-1169.7
NC_013592:446092:4530214530214545441524Dickeya dadantii Ech586, complete genometype I restriction-modification system, M subunit9e-1169.3
NC_017515:1429317:1439167143916714407081542Neisseria meningitidis M04-240196 chromosome, complete genometype I restriction-modification system, M subunit9e-1169.3
NC_017517:867595:8778948778948794351542Neisseria meningitidis M01-240355 chromosome, complete genometype I restriction-modification system, M subunit9e-1169.3
NC_012881:1802000:1823999182399918265692571Desulfovibrio salexigens DSM 2638, complete genomeN-6 DNA methylase8e-1169.3
NC_017514:1396000:1404288140428814058291542Neisseria meningitidis M01-240149 chromosome, complete genometype I restriction-modification system, M subunit8e-1169.3
NC_012912:1053618:1073108107310810747151608Dickeya zeae Ech1591, complete genometype I restriction-modification system, M subunit7e-1169.3
NC_015873:63487:6348763487649351449Megasphaera elsdenii DSM 20460, complete genomeN-6 DNA methylase1e-1068.9
NC_017505:841496:8519388519388534821545Neisseria meningitidis alpha710 chromosome, complete genometype I restriction enzyme EcoR124II M protein1e-1068.9
NC_009033:755226:7592987592987610161719Staphylothermus marinus F1, complete genomeN-6 DNA methylase1e-1068.9
NC_016590:1380092:1383778138377813862642487Burkholderia sp. YI23 chromosome 3, complete sequencetype I restriction-modification system, M subunit1e-1068.9
NC_015953:2349503:2377301237730123799612661Streptomyces sp. SirexAA-E chromosome, complete genomeN-6 DNA methylase1e-1068.9
NC_008782:3800500:3812794381279438143201527Acidovorax sp. JS42, complete genomeN-6 DNA methylase1e-1068.9
NC_016620:781995:7940057940057957471743Bacteriovorax marinus SJ, complete genomeputative type I restriction enzyme modification protein9e-1168.9
NC_010994:859500:8714178714178739092493Rhizobium etli CIAT 652, complete genomeprobable type I restriction-modification system protein, methyltransferase subunit1e-1068.6
NC_007925:4060635:4065251406525140667201470Rhodopseudomonas palustris BisB18, complete genomeN-6 DNA methylase1e-1068.6
NC_014217:2760898:2775000277500027765171518Starkeya novella DSM 506 chromosome, complete genometype I restriction-modification system, M subunit1e-1068.6
NC_016803:2431672:2453012245301224545201509Desulfovibrio desulfuricans ND132 chromosome, complete genometype I restriction-modification system, M subunit1e-1068.6
NC_020164:89214:1063761063761079321557Staphylococcus warneri SG1, complete genometype I restriction-modification system methyltransferase subunit1e-1068.6
NC_015634:2595500:2613693261369326162572565Bacillus coagulans 2-6 chromosome, complete genometype I restriction-modification system, M subunit2e-1068.2
NC_016147:1961000:1972377197237719738641488Pseudoxanthomonas spadix BD-a59 chromosome, complete genomeN-6 DNA methylase2e-1068.2
NC_004347:4441110:4441110444111044427231614Shewanella oneidensis MR-1, complete genometype I restriction-modification system, M subunit2e-1068.2
NC_008571:744500:7479517479517495941644Gramella forsetii KT0803, complete genometype I restriction-modification system methyltra nsferase subunit2e-1068.2
NC_011601:4856717:4867089486708948686451557Escherichia coli O127:H6 str. E2348/69 chromosome, complete genometype I restriction-modification enzyme M subunit2e-1068.2
NC_016803:3502749:3528606352860635302281623Desulfovibrio desulfuricans ND132 chromosome, complete genometype I restriction-modification system, M subunit2e-1068.2
NC_016023:1959255:1966227196622719687912565Bacillus coagulans 36D1 chromosome, complete genometype I restriction-modification system, M subunit2e-1067.8
NC_021064:793098:8015348015348042032670Propionibacterium avidum 44067, complete genomeN-6 DNA methylase2e-1067.8
NC_016589:183432:2013022013022029151614Burkholderia sp. YI23 chromosome 1, complete sequencetype I restriction-modification system, M subunit3e-1067.8
NC_018867:1407163:1446014144601414476031590Dehalobacter sp. CF chromosome, complete genomeType I restriction-modification system specificity subunit3e-1067.8
NC_015138:1:6354635478051452Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completeN-6 DNA methylase3e-1067.4
NC_013929:3299736:3325164332516433276052442Streptomyces scabiei 87.22 chromosome, complete genometype I restriction modification system protein3e-1067.4
NC_014624:2668157:2706473270647327082751803Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-1067.4
NC_017516:1439775:1450139145013914516801542Neisseria meningitidis H44/76 chromosome, complete genometype I restriction-modification system, M subunit3e-1067.4
NC_003112:844000:8523678523678539111545Neisseria meningitidis MC58, complete genometype I restriction enzyme EcoR124II M protein3e-1067.4
NC_015761:299386:3099813099813115371557Salmonella bongori NCTC 12419, complete genometype I restriction-modification methylase4e-1067
NC_010571:1334000:1342180134218013438231644Opitutus terrae PB90-1, complete genometype I restriction-modification system, M subunit4e-1067
NC_015942:668775:6861016861016882152115Acidithiobacillus ferrivorans SS3 chromosome, complete genomeN-6 DNA methylase4e-1067
NC_016002:1048420:1076166107616610786972532Pseudogulbenkiania sp. NH8B, complete genometype I restriction-modification system methylation subunit4e-1067
NC_013716:3512950:3527236352723635287381503Citrobacter rodentium ICC168, complete genomeputative type I restriction modification system HsdM component4e-1067
NC_016514:506611:5248585248585264141557Enterobacter cloacae EcWSU1 chromosome, complete genometype I restriction enzyme M protein4e-1067
NC_003116:988000:9982599982599998031545Neisseria meningitidis Z2491, complete genometype I restriction-modification system protein6e-1066.6
NC_017512:760000:7690747690747706181545Neisseria meningitidis WUE 2594, complete genomeputative type I restriction-modification system M protein6e-1066.6
NC_009712:1008000:1012783101278310142161434Candidatus Methanoregula boonei 6A8, complete genomeN-6 DNA methylase6e-1066.6
NC_016838:85487:9460994609961651557Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1,type I restriction enzyme5e-1066.6
NC_009439:608500:6118046118046145302727Pseudomonas mendocina ymp, complete genometype I restriction-modification system, M subunit5e-1066.6
NC_006513:1547092:1551214155121415528451632Azoarcus sp. EbN1, complete genomeType I site-specific deoxyribonuclease, methylase subunit8e-1066.2
NC_014752:1530000:1539453153945315409971545Neisseria lactamica ST-640, complete genometype I restriction-modification system protein8e-1066.2
NC_010682:460523:4830064830064846191614Ralstonia pickettii 12J chromosome 1, complete sequencetype I restriction-modification system, M subunit7e-1066.2
NC_015635:4864349:4881431488143148838872457Microlunatus phosphovorus NM-1, complete genometype I restriction-modification system modification subunit7e-1066.2
NC_011832:913994:9261469261469275821437Candidatus Methanosphaerula palustris E1-9c, complete genomeN-6 DNA methylase6e-1066.2
NC_015942:2213710:2225120222512022274712352Acidithiobacillus ferrivorans SS3 chromosome, complete genometype I restriction-modification system, M subunit6e-1066.2
NC_009953:3224412:3234966323496632373982433Salinispora arenicola CNS-205 chromosome, complete genomeN-6 DNA methylase6e-1066.2
NC_006672:47610:6761967619691451527Gluconobacter oxydans 621H plasmid pGOX1, complete sequenceType I restriction enzyme M protein1e-0965.9
NC_019904:5308998:5315018531501853166011584Echinicola vietnamensis DSM 17526 chromosome, complete genometype I restriction system adenine methylase HsdM1e-0965.9
NC_014814:2588628:2628221262822126296541434Mycobacterium sp. Spyr1 chromosome, complete genometype I restriction-modification system methyltransferase subunit8e-1065.9
NC_018691:3437821:3444274344427434457551482Alcanivorax dieselolei B5 chromosome, complete genomeSite-specific DNA-methyltransferase (Adenine-specific)1e-0965.5
NC_010468:4059436:406968540696854070347663Escherichia coli ATCC 8739, complete genome1e-0965.5
NC_007930:21793:2782027820292171398Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,Modification subunit1e-0965.5
NC_009052:4335754:4342999434299943446421644Shewanella baltica OS155, complete genometype I restriction-modification system, M subunit2e-0965.1
NC_007954:3887488:3899904389990439017961893Shewanella denitrificans OS217, complete genomeN-6 DNA methylase3e-0964.3
NC_004369:256262:2779402779402803422403Corynebacterium efficiens YS-314, complete genomeputative restriction enzyme subunit M3e-0964.3
NC_007622:416000:4203564203564219121557Staphylococcus aureus RF122, complete genometype I site-specific deoxyribonuclease4e-0963.9
NC_008786:3915000:3921610392161039232171608Verminephrobacter eiseniae EF01-2, complete genometype I restriction-modification system, M subunit4e-0963.9
NC_016012:665171:6734126734126749981587Candidatus Arthromitus sp. SFB-rat-Yit, complete genometype I restriction-modification system, M subunit3e-0963.9
NC_014934:3786132:3799748379974838024652718Cellulophaga algicola DSM 14237 chromosome, complete genometype i restriction-modification system, m subunit3e-0963.9
NC_016612:2009927:2017275201727520185281254Klebsiella oxytoca KCTC 1686 chromosome, complete genomeN-6 DNA methylase5e-0963.5
NC_002758:475516:4755164755164770721557Staphylococcus aureus subsp. aureus Mu50, complete genomeprobable type I site-specific deoxyribonuclease LldI chain5e-0963.5
NC_007086:1457531:1466423146642314679311509Xanthomonas campestris pv. campestris str. 8004, complete genometype I restriction enzyme M protein4e-0963.5
NC_003902:3430051:3442864344286434443721509Xanthomonas campestris pv. campestris str. ATCC 33913, completetype I restriction enzyme M protein4e-0963.5
NC_010688:1435694:1444562144456214460701509Xanthomonas campestris pv. campestris, complete genometype I site-specific DNA-methyltransferase catalytic subunit4e-0963.5
NC_013450:412122:4121224121224136781557Staphylococcus aureus subsp. aureus ED98, complete genometype I restriction-modification system, M subunit4e-0963.5
NC_007793:459045:4574964574964590521557Staphylococcus aureus subsp. aureus USA300, complete genometype I restriction-modification system, M subunit6e-0963.2
NC_010079:458940:4573914573914589471557Staphylococcus aureus subsp. aureus USA300_TCH1516, completetype I site-specific deoxyribonuclease methyltransferase subunit6e-0963.2
NC_009487:486000:4862614862614878171557Staphylococcus aureus subsp. aureus JH9 chromosome, completetype I restriction-modification system, M subunit6e-0963.2
NC_009632:486331:4863314863314878871557Staphylococcus aureus subsp. aureus JH1 chromosome, completetype I restriction-modification system, M subunit6e-0963.2
NC_009641:448640:4470914470914486471557Staphylococcus aureus subsp. aureus str. Newman chromosome,type I restriction-modification system, methyltransferase subunit6e-0963.2
NC_017341:472685:4711364711364726921557Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,Type I restriction-modification system methyltransferase subunit6e-0963.2
NC_017343:416834:4152854152854168411557Staphylococcus aureus subsp. aureus ECT-R 2, complete genometype I restriction-modification system, M subunit6e-0963.2
NC_017347:469024:4674754674754690311557Staphylococcus aureus subsp. aureus T0131 chromosome, completeType I restriction-modification system, methyltransferase subunit6e-0963.2
NC_014638:183115:2082312082312097931563Bifidobacterium bifidum PRL2010 chromosome, complete genometype I restriction-modification system methyltransferase subunit6e-0963.2
NC_002745:450000:4510004510004525561557Staphylococcus aureus subsp. aureus N315, complete genomeprobable type I site-specific deoxyribonuclease LldI chain hsdM9e-0962.8
NC_019977:1353332:1359134135913413615302397Methanomethylovorans hollandica DSM 15978, complete genometype I restriction system adenine methylase HsdM8e-0962.8
NC_013949:939695:9473529473529489801629Helicobacter mustelae 12198 chromosome, complete genometype I restriction-modification system M protein8e-0962.8
NC_011283:5011497:5020856502085650233002445Klebsiella pneumoniae 342 chromosome, complete genometype I restriction-modification system, M subunit8e-0962.8
NC_018604:2579000:2605108260510826065921485Brachyspira pilosicoli WesB complete genomeType I restriction-modification system M subunit7e-0962.8
NC_009665:2602000:2611940261194026144832544Shewanella baltica OS185 chromosome, complete genometype I restriction-modification system, M subunit1e-0862.4
NC_012491:743883:7513647513647529111548Brevibacillus brevis NBRC 100599, complete genometype I restriction modification system DNA methylase1e-0862.4
NC_016803:593484:6031586031586045941437Desulfovibrio desulfuricans ND132 chromosome, complete genomeadenine-specific DNA-methyltransferase9e-0962.4
NC_017338:436711:4367114367114382671557Staphylococcus aureus subsp. aureus JKD6159 chromosome, completeType I restriction-modification system methyltransferase subunit, HsdM_19e-0962.4
NC_012779:3316877:3334832333483233372702439Edwardsiella ictaluri 93-146, complete genometype I restriction enzyme M protein (HsdM)1e-0861.6
NC_012759:4501206:4517966451796645195551590Escherichia coli BW2952 chromosome, complete genomeDNA methylase M2e-0861.6
AC_000091:4569379:4586139458613945877281590Escherichia coli W3110 DNA, complete genomeDNA methylase M2e-0861.6
NC_011901:1860887:1892757189275718951562400Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completetype I restriction-modification system specificity subunit2e-0861.2
NC_011745:3443371:3471816347181634737051890Escherichia coli ED1a chromosome, complete genomeputative Restriction enzyme subunit alpha2e-0861.2
NC_007519:3391090:3391090339109033926041515Desulfovibrio alaskensis G20 chromosome, complete genometype I restriction-modification system methylation subunit-like2e-0861.2
NC_014837:2458780:2475624247562424775221899Pantoea sp. At-9b chromosome, complete genomeN-6 DNA methylase2e-0861.2
NC_015703:3880903:3902668390266839041281461Runella slithyformis DSM 19594 chromosome, complete genomeN-6 DNA methylase3e-0860.8
NC_009943:1499111:1505694150569415097824089Candidatus Desulfococcus oleovorans Hxd3, complete genomeN-6 DNA methylase3e-0860.8
NC_014970:530748:5333525333525348931542Mycoplasma haemofelis str. Langford 1, complete genometype I restriction-modification system, M subunit3e-0860.8
NC_014365:2810405:2834613283461328361991587Desulfarculus baarsii DSM 2075 chromosome, complete genomeSite-specific DNA-methyltransferase (adenine-specific)3e-0860.8
NC_011149:4677412:4700220470022047017101491Salmonella enterica subsp. enterica serovar Agona str. SL483,N-6 DNA methylase4e-0860.5
NC_011830:4187362:4195014419501441965911578Desulfitobacterium hafniense DCB-2, complete genometype I restriction-modification system, M subunit4e-0860.5
NC_015676:794639:8021168021168036061491Methanosalsum zhilinae DSM 4017 chromosome, complete genomeN-6 DNA methylase3e-0860.5
NC_017271:1289278:1294022129402212967662745Xanthomonas campestris pv. raphani 756C chromosome, completetype I restriction-modification system specificity subunit5e-0860.1
NC_015578:1940097:1951205195120519527731569Treponema primitia ZAS-2 chromosome, complete genometype I restriction-modification system, M subunit5e-0860.1
NC_016816:1137904:1155453115545311569971545Pantoea ananatis LMG 5342, complete genomeDNA methylase M5e-0860.1
NC_002937:1764117:1783988178398817855081521Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetype I restriction-modification system, M subunit5e-0860.1
NC_013508:3188978:3230042323004232324802439Edwardsiella tarda EIB202, complete genometype I restriction-modification system, M subunit5e-0860.1
NC_020450:875757:8943988943988959451548Lactococcus lactis subsp. lactis IO-1 DNA, complete genometype I restriction enzyme M protein5e-0860.1
NC_018868:1352000:1367654136765413691111458Simiduia agarivorans SA1 = DSM 21679 chromosome, complete genomeN-6 DNA methylase6e-0859.7
NC_005139:2201820:2216705221670522182341530Vibrio vulnificus YJ016 chromosome I, complete sequencetype I restriction-modification system methyltransferase subunit7e-0859.3
NC_009434:695582:7187087187087202551548Pseudomonas stutzeri A1501, complete genometype I restriction-modification system, M subunit7e-0859.3
NC_018876:1061682:1091351109135110928561506Methanolobus psychrophilus R15 chromosome, complete genomesite-specific DNA-methyltransferase (adenine-specific), subunit M1e-0758.9
NC_007498:3399478:3417672341767234197982127Pelobacter carbinolicus DSM 2380, complete genometype I restriction-modification system methyltransferase subunit1e-0758.9
NC_003901:2727361:2736501273650127389272427Methanosarcina mazei Go1, complete genometype I restriction-modification system specificity subunit1e-0758.9
NC_003272:3275413:3278898327889832808711974Nostoc sp. PCC 7120, complete genometype I restriction enzyme, modification chain1e-0758.5
NC_009943:272158:2857762857762882022427Candidatus Desulfococcus oleovorans Hxd3, complete genometype I restriction-modification system, M subunit2e-0758.2
NC_014206:2807879:2820053282005328215341482Geobacillus sp. C56-T3 chromosome, complete genomeadenine-specific DNA-methyltransferase2e-0757.8
NC_015844:3159046:3160449316044931619121464Zobellia galactanivorans, complete genometype I restriction enzyme ZgaDI, M subunit3e-0757.4
NC_016109:7631165:7640167764016776416061440Kitasatospora setae KM-6054, complete genomeputative DNA methyltransferase4e-0757
NC_019902:1863162:1875343187534318778262484Thioalkalivibrio nitratireducens DSM 14787, complete genomeType I restriction-modification system, DNA-methyltransferase subunit M4e-0757
NC_014034:1036652:1046486104648610479551470Rhodobacter capsulatus SB1003 chromosome, complete genometype I restriction-modification system RcaSBIP subunit M4e-0757
NC_010610:1178430:1187874118787411892471374Lactobacillus fermentum IFO 3956, complete genomeputative type I site-specific deoxyribonuclease6e-0756.6
NC_016593:956839:9600909600909615711482Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completeN-6 DNA methylase7e-0756.2
NC_009328:814530:8379108379108393911482Geobacillus thermodenitrificans NG80-2 chromosome, complete genomeType I restriction enzyme StySPI M protein9e-0755.8
NC_009720:1248866:1264446126444612659061461Xanthobacter autotrophicus Py2, complete genomeN-6 DNA methylase1e-0655.8
NC_012587:128845:1471651471651487001536Rhizobium sp. NGR234, complete genomeN-6 DNA methylase1e-0655.5
NC_021177:7462000:7473467747346774763822916Streptomyces fulvissimus DSM 40593, complete genomeN-6 DNA methylase1e-0655.5
NC_013411:284461:2899052899052918091905Geobacillus sp. Y412MC61, complete genomeN-6 DNA methylase7e-0653.1
NC_014915:2427000:2447679244767924495831905Geobacillus sp. Y412MC52 chromosome, complete genomeN-6 DNA methylase7e-0653.1
NC_016612:2009927:2029011202901120304261416Klebsiella oxytoca KCTC 1686 chromosome, complete genometype I restriction-modification system M subunit9e-0652.4