Pre_GI: BLASTP Hits

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Query: NC_009882:563830:563830 Rickettsia rickettsii str. 'Sheila Smith', complete genome

Start: 563830, End: 564159, Length: 330

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from from a patient with Rocky Mountain spotted fever. Causative agent for Rocky Mountain Spotted Fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia rickettsii was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011761:1838000:1855079185507918581833105Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completetransporter AcrB/AcrD/AcrF family6e-1579.3
NC_011206:1719000:1738671173867117417753105Acidithiobacillus ferrooxidans ATCC 53993, complete genomeacriflavin resistance protein6e-1579.3
NC_015057:241103:2613782613782648933516Acidobacterium sp. MP5ACTX9 plasmid pACIX901, complete sequenceacriflavin resistance protein1e-1065.5
NC_005966:3334864:3334864333486433380253162Acinetobacter sp. ADP1, complete genomemultidrug transport protein (RND family)1e-1168.2
NC_005966:3334864:3331691333169133348673177Acinetobacter sp. ADP1, complete genomemultidrug transport protein, outer membrane (RND family)2e-0961.2
NC_009633:168266:2176232176232207723150Alkaliphilus metalliredigens QYMF chromosome, complete genomeacriflavin resistance protein1e-0652
NC_021150:1823874:1836634183663418397533120Azotobacter vinelandii CA6, complete genomeheavy metal efflux pump, CzcA family2e-0650.8
NC_012560:1823861:1836621183662118397403120Azotobacter vinelandii DJ, complete genomeheavy metal efflux pump, CzcA family2e-0650.8
NC_009614:2431005:2431005243100524340403036Bacteroides vulgatus ATCC 8482 chromosome, complete genomemultidrug efflux membrane fusion protein1e-0652
NC_007951:1711223:1714538171453817176603123Burkholderia xenovorans LB400 chromosome 1, complete sequenceRND multidrug efflux pump, AcrB/AcrD/AcrF family3e-1063.9
NC_010546:4923496:2458245856193162Cyanothece sp. ATCC 51142 chromosome circular, complete sequencecation efflux system membrane protein1e-0652
NC_011726:1605600:1615822161582216189863165Cyanothece sp. PCC 8801, complete genomeheavy metal efflux pump, CzcA family2e-0754.7
NC_015388:1612000:1612278161227816154063129Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeacriflavin resistance protein1e-1892
NC_015663:4950000:5016795501679550199173123Enterobacter aerogenes KCTC 2190 chromosome, complete genomemultidrug efflux system subunit MdtB4e-0856.6
NC_015968:3023048:3040100304010030432223123Enterobacter asburiae LF7a chromosome, complete genomeMultidrug resistance protein mdtB4e-0856.6
NC_015968:3023048:3043223304322330463003078Enterobacter asburiae LF7a chromosome, complete genomeMultidrug resistance protein mdtC6e-0856.2
NC_014618:1700784:1717954171795417210313078Enterobacter cloacae SCF1 chromosome, complete genomeacriflavin resistance protein1e-0755.5
NC_014618:1700784:1721032172103217241543123Enterobacter cloacae SCF1 chromosome, complete genomeacriflavin resistance protein2e-0754.7
NC_014121:3453815:3470847347084734739693123Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completemultidrug efflux system subunit MdtB2e-0857.4
NC_014121:3453815:3473970347397034770473078Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completemultidrug efflux system subunit MdtC5e-0959.7
NC_004431:2444972:2444972244497224480493078Escherichia coli CFT073, complete genomeHypothetical protein yegO3e-0857
NC_011146:63912:7497174971780723102Geobacter bemidjiensis Bem, complete genomeacriflavin resistance protein5e-2199.8
NC_010814:155834:1558341558341589323099Geobacter lovleyi SZ, complete genomeacriflavin resistance protein4e-0650.1
NC_010125:3467379:3464218346421834673823165Gluconacetobacter diazotrophicus PAl 5, complete genomeputative multidrug resistance protein mdtB2e-0961.2
NC_010125:3467379:3467379346737934706843306Gluconacetobacter diazotrophicus PAl 5, complete genomeputative multidrug resistance protein mdtC4e-0650.1
NC_012559:1228280:1250110125011012530942985Laribacter hongkongensis HLHK9, complete genomeprobable drug efflux pump transmembrane protein4e-0856.6
NC_012559:1228280:1246921124692112486901770Laribacter hongkongensis HLHK9, complete genomeacriflavin resistance protein1e-0962
NC_011894:585637:5977635977636008673105Methylobacterium nodulans ORS 2060, complete genomeacriflavin resistance protein1e-1478.6
NC_015177:2972701:2988929298892929920303102Pedobacter saltans DSM 12145 chromosome, complete genomeacriflavin resistance protein9e-0648.9
NC_016818:859181:8843448843448875383195Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completecation/multidrug efflux pump1e-1272
NC_020541:1827689:1838006183800618411163111Rhodanobacter sp. 2APBS1, complete genomecation/multidrug efflux pump1e-0858.5
NC_017058:862000:882218882218882370153Rickettsia australis str. Cutlack chromosome, complete genomeRND family efflux transporter7e-1269.3
NC_017044:564000:564181564181564696516Rickettsia parkeri str. Portsmouth chromosome, complete genomeRND family efflux transporter7e-54208
NC_016909:563727:563727563727564056330Rickettsia rickettsii str. Arizona chromosome, complete genomeacriflavin resistance plasma membrane protein9e-57218
NC_016908:563747:563747563747564076330Rickettsia rickettsii str. Colombia chromosome, complete genomeacriflavin resistance plasma membrane protein9e-57218
NC_016911:563822:563822563822564151330Rickettsia rickettsii str. Hauke chromosome, complete genomeacriflavin resistance plasma membrane protein9e-57218
NC_016914:563941:563941563941564270330Rickettsia rickettsii str. Hino chromosome, complete genomeacriflavin resistance plasma membrane protein9e-57218
NC_010263:563814:563814563814564149336Rickettsia rickettsii str. Iowa, complete genomeacriflavin resistance plasma membrane protein6e-57219
NC_011149:2179592:2176515217651521795953081Salmonella enterica subsp. enterica serovar Agona str. SL483,multidrug resistance protein MdtC2e-0857.4
NC_011147:792489:8200908200908232123123Salmonella enterica subsp. enterica serovar Paratyphi A strmultidrug efflux system subunit MdtB2e-0961.2
NC_011147:792489:8170098170098200893081Salmonella enterica subsp. enterica serovar Paratyphi A strmultidrug efflux system subunit MdtC2e-0857.8
NC_006511:792543:8201448201448232663123Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative RND-family transporter protein2e-0961.2
NC_006511:792543:8170638170638201433081Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative RND-family transporter protein2e-0857.8
NC_012125:1632150:1662094166209416652163123Salmonella enterica subsp. enterica serovar Paratyphi C strainmultidrug efflux system subunit MdtB2e-0960.8
NC_012125:1632150:1659013165901316620933081Salmonella enterica subsp. enterica serovar Paratyphi C strainmultidrug efflux system subunit MdtC2e-0857.8
NC_003198:2179688:2176611217661121796913081Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative RND-family transporter protein2e-0857.4
NC_016832:799764:8272808272808304023123Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Multidrug resistance protein mdtB2e-0961.2
NC_016832:799764:8241998241998272793081Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Multidrug resistance protein mdtC2e-0857.4
NC_004631:799810:8242458242458273253081Salmonella enterica subsp. enterica serovar Typhi Ty2, completeputative RND-family transporter protein2e-0857.4
NC_004631:799810:8273268273268304483123Salmonella enterica subsp. enterica serovar Typhi Ty2, completeputative RND-family transporter protein2e-0961.2
NC_014152:927969:9461989461989493293132Thermincola sp. JR, complete genomeacriflavin resistance protein6e-0649.7
NC_016148:463840:4638404638404669593120Thermovirga lienii DSM 17291 chromosome, complete genomeacriflavin resistance protein6e-0752.8
NC_008786:2573558:2592103259210325951833081Verminephrobacter eiseniae EF01-2, complete genomeacriflavin resistance protein1e-1375.5
NC_008786:2573558:2595180259518025984493270Verminephrobacter eiseniae EF01-2, complete genomeacriflavin resistance protein4e-0856.6
NC_009720:813157:8223848223848255483165Xanthobacter autotrophicus Py2, complete genomeacriflavin resistance protein4e-1063.2
NC_013722:2919560:2927068292706829301243057Xanthomonas albilineans, complete genomeprobable rnd superfamily protein1e-0652.4
NC_013892:2689645:2712486271248627155693084Xenorhabdus bovienii SS-2004 chromosome, complete genomemultidrug transporter, outer membrane (RND family)9e-0958.9
NC_013892:2689645:2709319270931927124893171Xenorhabdus bovienii SS-2004 chromosome, complete genomeRND family multidrug transporter2e-1064.3
NC_002488:2235883:2257189225718922604223234Xylella fastidiosa 9a5c, complete genomeacriflavin resistance protein D2e-1684.3
NC_014029:3171627:3197357319735732005153159Yersinia pestis Z176003 chromosome, complete genomeAcrB/AcrD/AcrF family membrane protein6e-1166.2
NC_014029:3171627:3194286319428631973603075Yersinia pestis Z176003 chromosome, complete genomeAcrB/AcrD/AcrF family membrane protein3e-0960.5