Pre_GI: BLASTP Hits

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Query: NC_009882:167350:169030 Rickettsia rickettsii str. 'Sheila Smith', complete genome

Start: 169030, End: 169773, Length: 744

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from from a patient with Rocky Mountain spotted fever. Causative agent for Rocky Mountain Spotted Fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia rickettsii was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016914:167537:169210169210169953744Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein3e-143507
NC_016911:167398:169071169071169814744Rickettsia rickettsii str. Hauke chromosome, complete genomehypothetical protein3e-143507
NC_016908:167423:169103169103169846744Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein3e-143507
NC_010263:167450:169123169123169866744Rickettsia rickettsii str. Iowa, complete genomerhodanese-related sulfurtransferase3e-143507
NC_016915:162841:169296169296170039744Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein4e-143506
NC_016930:165376:167064167064167807744Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein9e-143505
NC_003103:164972:166684166684167427744Rickettsia conorii str. Malish 7, complete genomehypothetical protein6e-141499
NC_009881:166500:172853172853173596744Rickettsia akari str. Hartford, complete genomehypothetical protein3e-135481
NC_009879:141000:147028147028147777750Rickettsia canadensis str. McKiel, complete genomehypothetical protein1e-129462
NC_016929:141972:147993147993148742750Rickettsia canadensis str. CA410 chromosome, complete genomehypothetical protein1e-128459
NC_017066:140853:149053149053149796744Rickettsia typhi str. TH1527 chromosome, complete genomehypothetical protein6e-126449
NC_017062:141270:149470149470150213744Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein6e-126449
NC_006142:140853:149053149053149796744Rickettsia typhi str. Wilmington, complete genomehypothetical protein6e-126449
NC_009883:277409:279122279122279868747Rickettsia bellii OSU 85-389, complete genomehypothetical protein7e-125446
NC_000963:141500:148519148519149262744Rickettsia prowazekii str. Madrid E, complete genomehypothetical protein1e-124445
NC_017048:484000:490683490683491426744Rickettsia prowazekii str. GvV257 chromosome, complete genomehypothetical protein1e-124445
NC_017049:140000:146718146718147461744Rickettsia prowazekii str. Chernikova chromosome, complete genomehypothetical protein1e-124445
NC_017050:141500:148517148517149260744Rickettsia prowazekii str. Katsinyian chromosome, complete genomehypothetical protein1e-124445
NC_017051:140000:146722146722147465744Rickettsia prowazekii str. Dachau chromosome, complete genomehypothetical protein1e-124445
NC_017056:141500:148527148527149270744Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomehypothetical protein1e-124445
NC_017057:142000:148739148739149482744Rickettsia prowazekii str. RpGvF24 chromosome, complete genomehypothetical protein1e-124445
NC_010793:1695716:171276517127651713514750Orientia tsutsugamushi str. Ikeda, complete genomePredicted sulfurtransferase5e-70264
NC_009488:767525:785940785940786689750Orientia tsutsugamushi str. Boryong, complete genomesulfurtransferase6e-65247
NC_010677:1296000:131462913146291315615987Francisella tularensis subsp. mediasiatica FSC147, complete genomeputative rhodanese, sulfurtransferase4e-63241
NC_007947:2447635:247631624763162477287972Methylobacillus flagellatus KT, complete genomeRhodanese-like protein2e-60232
NC_008783:1101973:112046311204631121380918Bartonella bacilliformis KC583, complete genomerhodanese-like domain protein5e-60230
NC_020300:1241968:125805812580581258975918Bartonella australis Aust/NH1, complete genomeputative rhodanese-related sulfurtransferase protein1e-59229
NC_014932:1232346:127800112780011278918918Bartonella clarridgeiae 73, complete genomehypothetical protein6e-59227
NC_005956:1402500:142345214234521424366915Bartonella henselae str. Houston-1, complete genomehypothetical protein9e-59226
NC_012969:2476318:247871924787192479717999Methylovorus glucosetrophus SIP3-4 chromosome, complete genomeRhodanese domain-containing protein5e-58224
NC_014733:2363838:236948323694832370442960Methylovorus sp. MP688 chromosome, complete genomerhodanese domain protein6e-58224
NC_012846:1741000:176285217628521763769918Bartonella grahamii as4aup, complete genomeputative rhodanese-related sulfurtransferase protein1e-57223
NC_005955:1166521:118600111860011186915915Bartonella quintana str. Toulouse, complete genomehypothetical protein4e-57221
NC_007797:1016456:102454910245491025388840Anaplasma phagocytophilum HZ, complete genomerhodanese domain protein9e-57220
NC_005071:1111605:113801511380151138947933Prochlorococcus marinus str. MIT 9313, complete genomehypothetical protein7e-54210
NC_010475:1563578:157834315783431579239897Synechococcus sp. PCC 7002, complete genomeRhodanese-like sulfurtransferase7e-54210
NC_007798:213069:216393216393217301909Neorickettsia sennetsu str. Miyayama, complete genomerhodanese domain protein4e-53207
NC_013009:225722:227614227614228498885Neorickettsia risticii str. Illinois, complete genomerhodanese domain protein3e-49195
NC_006270:3418097:341809734180973419065969Bacillus licheniformis ATCC 14580, complete genomehypothetical protein5e-48191
NC_006322:3418268:341826834182683419236969Bacillus licheniformis ATCC 14580, complete genomehypothetical protein5e-48191
NC_004193:375416:601147601147602118972Oceanobacillus iheyensis HTE831, complete genomehypothetical protein4e-47187
NC_004461:245768:261489261489262451963Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-43175
NC_006576:2328427:235127123512712352080810Synechococcus elongatus PCC 6301, complete genomehypothetical protein5e-43174
NC_002953:2773000:277524127752412776197957Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein6e-43174
NC_003923:2794686:279590127959012796857957Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein6e-43174
NC_018643:641360:659028659028659936909Alpha proteobacterium HIMB5 chromosome, complete genomerhodanese-like protein1e-41169
NC_019904:2095971:211581621158162116799984Echinicola vietnamensis DSM 17526 chromosome, complete genomesulfurtransferase3e-35148
NC_010084:1054000:1055060105506010560791020Burkholderia multivorans ATCC 17616 chromosome 1, completerhodanese superfamily protein2e-34146
NC_010830:1171781:117556011755601176516957Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein2e-32139
NC_010688:2781624:278162427816242782385762Xanthomonas campestris pv. campestris, complete genomehypothetical protein4e-31135
NC_016510:1958453:1971686197168619730561371Flavobacterium columnare ATCC 49512 chromosome, complete genomerhodanese domain-containing protein5e-30131
NC_014924:1701952:171994517199451720727783Pseudoxanthomonas suwonensis 11-1 chromosome, complete genomeRhodanese domain protein1e-28127
NC_020302:3014483:301511030151103016024915Corynebacterium halotolerans YIM 70093 = DSM 44683, completeputative rhodanese-related sulfurtransferase1e-26119
NC_020156:1565500:1586108158610815871421035Nonlabens dokdonensis DSW-6, complete genomesulfurtransferase2e-26119
NC_013174:650986:656022656022656936915Jonesia denitrificans DSM 20603, complete genomeRhodanese domain protein2e-25116
NC_020211:2012480:2017792201779220188591068Serratia marcescens WW4, complete genomeputative rhodanese-related sulfurtransferase3e-25115
NC_015968:1709680:1730549173054917315981050Enterobacter asburiae LF7a chromosome, complete genomehypothetical protein4e-25114
NC_012912:1788308:1834173183417318352341062Dickeya zeae Ech1591, complete genomeRhodanese domain protein4e-24111
NC_014306:1810548:1825626182562618266751050Erwinia billingiae Eb661, complete genomehypothetical protein3e-22105
NC_017168:2999514:3010461301046130115281068Yersinia pestis A1122 chromosome, complete genomeputative rhodanese-related sulfurtransferase3e-22105
NC_003143:2741478:2750905275090527519721068Yersinia pestis CO92, complete genomehypothetical protein3e-22105
NC_004088:1909880:1919805191980519209261122Yersinia pestis KIM, complete genomehypothetical protein4e-22105
NC_005810:2508671:2520829252082925219501122Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-22105
NC_008150:2173708:218271521827152183500786Yersinia pestis Antiqua, complete genomehypothetical protein1e-1997.1