Some Help

Query: NC_009727:1177390 Coxiella burnetii Dugway 7E9-12, complete genome

Start: 1177390, End: 1200516, Length: 23127

Host Lineage: Coxiella burnetii; Coxiella; Coxiellaceae; Legionellales; Proteobacteria; Bacteria

General Information: Coxiella burnetii Dugway 5J108-111 was isolated from rodents in Utah, USA. This organism is widely distributed in nature and can cause infections in reptiles, birds, and mammals. It causes Q fever, or 'query' fever, an atypical pneumonia first associated with abattoir workers in Australia. Transmission may be through insect vectors such as ticks that have bitten an infected wild or domesticated animal, or through an aerosol produced by domesticated animals such as sheep or cattle. The presence of a plasmid is believed to be associated with virulence and pathogenicity, however C. burnetii isolates containing plasmid QpDG are avirulent in guinea pigs and plasmidless isolates have been associated with endocarditis in humans. Coxiella burnetii has a developmental life cycle, and can grow vegetatively through binary fission, or asymmetrically and produce a spore-like cell. The spore-like cell may enable the organism to exist extracellularly for small amounts of time. This bacterium is an obligate intracellular pathogen. It is endocytosed by a host cell, a macrophage for example, and lives and replicates inside the phagolysozome, a unique property of this organism. The genome encodes proteins that have a higher than average pI, which may enable adaptation to the acidic environment of the phagolysozome. The chromosome also contains genes for a number of detoxification and stress response proteins such as dismutases that allow growth in the oxidative environment. The type IV system is similar to the one found in Legionella, which may be important for intracellular survival. This organism produces numerous ankyrin-repeat proteins that may be involved in interactions with the host cell. The genome has 83 pseudogenes, which may be a result of the typical genome-wide degradation observed with other intracellular organisms and also has a group I intron in the 23S ribosomal RNA gene.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009727:357206*35720637934622141Coxiella burnetii Dugway 7E9-12, complete genome1e-63252BLASTN svgBLASTP svg
NC_002971:1379567*1379567140286123295Coxiella burnetii RSA 493, complete genome1e-60242BLASTN svgBLASTP svg
NC_011528:1769349*1769349179244023092Coxiella burnetii CbuK_Q154, complete genome8e-56226BLASTN svgBLASTP svg
NC_011528:535680*53568055489519216Coxiella burnetii CbuK_Q154, complete genome6e-38167BLASTN svgBLASTP svg
NC_011527:525759*52575954826022502Coxiella burnetii CbuG_Q212, complete genome2e-35159BLASTN svgBLASTP svg
NC_009727:1001203*1001203102529924097Coxiella burnetii Dugway 7E9-12, complete genome6e-35157BLASTN svgBLASTP svg
NC_002971:951102*95110297443323332Coxiella burnetii RSA 493, complete genome2e-32149BLASTN svgBLASTP svg
NC_010117:1633447*1633447165644522999Coxiella burnetii RSA 331, complete genome4e-30141BLASTN svgBLASTP svg
NC_002971:1545924*1545924156802322100Coxiella burnetii RSA 493, complete genome4e-30141BLASTN svgBLASTP svg
NC_002971:211331*21133124286731537Coxiella burnetii RSA 493, complete genome6e-26127BLASTN svgBLASTP svg
NC_011527:953442*95344297731923878Coxiella burnetii CbuG_Q212, complete genome8e-22113BLASTN svgBLASTP svg
NC_011527:1688447*1688447171102422578Coxiella burnetii CbuG_Q212, complete genome3e-21111BLASTN svgBLASTP svg
NC_009727:766000*76600078929223293Coxiella burnetii Dugway 7E9-12, complete genome8e-19103BLASTN svgBLASTP svg
NC_011528:386417*38641740829821882Coxiella burnetii CbuK_Q154, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_010117:285230*28523030710321874Coxiella burnetii RSA 331, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_002971:1523065*1523065154336920305Coxiella burnetii RSA 493, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_010117:1461502*1461502148409922598Coxiella burnetii RSA 331, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_009727:1822877*1822877184654323667Coxiella burnetii Dugway 7E9-12, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_011528:1282691*1282691130313820448Coxiella burnetii CbuK_Q154, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_011527:1443076*1443076146250819433Coxiella burnetii CbuG_Q212, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_009727:1542000*1542000156409922100Coxiella burnetii Dugway 7E9-12, complete genome2e-1075.8BLASTN svgBLASTP svg