Some Help

Query: NC_009727:1177390:1195904 Coxiella burnetii Dugway 7E9-12, complete genome

Start: 1195904, End: 1196617, Length: 714

Host Lineage: Coxiella burnetii; Coxiella; Coxiellaceae; Legionellales; Proteobacteria; Bacteria

General Information: Coxiella burnetii Dugway 5J108-111 was isolated from rodents in Utah, USA. This organism is widely distributed in nature and can cause infections in reptiles, birds, and mammals. It causes Q fever, or 'query' fever, an atypical pneumonia first associated with abattoir workers in Australia. Transmission may be through insect vectors such as ticks that have bitten an infected wild or domesticated animal, or through an aerosol produced by domesticated animals such as sheep or cattle. The presence of a plasmid is believed to be associated with virulence and pathogenicity, however C. burnetii isolates containing plasmid QpDG are avirulent in guinea pigs and plasmidless isolates have been associated with endocarditis in humans. Coxiella burnetii has a developmental life cycle, and can grow vegetatively through binary fission, or asymmetrically and produce a spore-like cell. The spore-like cell may enable the organism to exist extracellularly for small amounts of time. This bacterium is an obligate intracellular pathogen. It is endocytosed by a host cell, a macrophage for example, and lives and replicates inside the phagolysozome, a unique property of this organism. The genome encodes proteins that have a higher than average pI, which may enable adaptation to the acidic environment of the phagolysozome. The chromosome also contains genes for a number of detoxification and stress response proteins such as dismutases that allow growth in the oxidative environment. The type IV system is similar to the one found in Legionella, which may be important for intracellular survival. This organism produces numerous ankyrin-repeat proteins that may be involved in interactions with the host cell. The genome has 83 pseudogenes, which may be a result of the typical genome-wide degradation observed with other intracellular organisms and also has a group I intron in the 23S ribosomal RNA gene.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010793:541040:563876563876564589714Orientia tsutsugamushi str. Ikeda, complete genomedienelactone hydrolase family protein1e-51202
NC_016147:1672482:168026216802621681044783Pseudoxanthomonas spadix BD-a59 chromosome, complete genomedienelactone hydrolase7e-39160
NC_008740:443274:484153484153484959807Marinobacter aquaeolei VT8, complete genomedienelactone hydrolase3e-38158
NC_016745:2229271:223625422362542237051798Oceanimonas sp. GK1 chromosome, complete genomedienelactone hydrolase3e-38158
NC_007759:512477:512477512477513358882Syntrophus aciditrophicus SB, complete genomedienelactone hydrolase family protein3e-38158
NC_006350:595893:640045640045640776732Burkholderia pseudomallei K96243 chromosome 1, complete sequencedienelactone hydrolase family protein1e-35149
NC_007434:788500:8055278055278065971071Burkholderia pseudomallei 1710b chromosome I, complete sequencedienelactone hydrolase family protein2e-34145
NC_003919:3396136:341344734134473414214768Xanthomonas axonopodis pv. citri str. 306, complete genomehypothetical protein5e-32137
NC_008260:2142311:215992621599262160702777Alcanivorax borkumensis SK2, complete genomedienelactone hydrolase family protein9e-32137
NC_007645:2922190:292345329234532924190738Hahella chejuensis KCTC 2396, complete genomeDienelactone hydrolase and related enzyme2e-27122
NC_013943:1019213:103424810342481034988741Denitrovibrio acetiphilus DSM 12809 chromosome, complete genomedienelactone hydrolase6e-26117
NC_014010:1392536:144333714433371444092756Candidatus Puniceispirillum marinum IMCC1322 chromosome, completedienelactone hydrolase1e-24113
NC_014166:1424754:142705514270551427786732Arcobacter nitrofigilis DSM 7299 chromosome, complete genomedienelactone hydrolase2e-24112
NC_021177:2309615:231507323150732315840768Streptomyces fulvissimus DSM 40593, complete genomeDienelactone hydrolase-related enzyme2e-21102
NC_016114:7116141:712538371253837126108726Streptomyces flavogriseus ATCC 33331 chromosome, complete genomedienelactone hydrolase4e-21101
NC_014532:110875:130703130703131464762Halomonas elongata DSM 2581, complete genomedienelactone hydrolase3e-2099
NC_009380:4944183:495015349501534950923771Salinispora tropica CNB-440 chromosome, complete genomedienelactone hydrolase3e-1582
NC_012912:4428111:445124244512424452069828Dickeya zeae Ech1591, complete genomeCarboxymethylenebutenolidase4e-1168.6
NC_020304:547036:557986557986558867882Desulfocapsa sulfexigens DSM 10523, complete genomedienelactone hydrolase-like enzyme2e-1066.2
NC_011663:1159070:115907011590701160050981Shewanella baltica OS223 chromosome, complete genomedienelactone hydrolase9e-1063.9
NC_008392:542000:542210542210542923714Burkholderia cepacia AMMD chromosome 3, complete sequenceCarboxymethylenebutenolidase4e-0962
NC_004347:1038253:104078910407891041751963Shewanella oneidensis MR-1, complete genomedienelactone hydrolase family protein1e-0860.1
NC_008321:977500:981944981944982906963Shewanella sp. MR-4, complete genomeTwin-arginine translocation pathway signal3e-0858.9
NC_011740:2986514:300866730086673009593927Escherichia fergusonii ATCC 35469, complete genomeputative enzyme6e-0858.2
NC_008322:3758500:376997637699763770938963Shewanella sp. MR-7, complete genomeTwin-arginine translocation pathway signal2e-0755.8