Pre_GI: BLASTP Hits

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Query: NC_009698:2649453:2656895 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 2656895, End: 2657692, Length: 798

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009697:2714668:271996827199682720765798Clostridium botulinum A str. ATCC 19397 chromosome, completeflagellar hook capping protein5e-128457
NC_010520:2860960:286840328684032869200798Clostridium botulinum A3 str. Loch Maree, complete genomeflagellar hook capping protein5e-128457
NC_017297:2854934:285493428549342855755822Clostridium botulinum F str. 230613 chromosome, complete genomeflagellar hook capping protein1e-121435
NC_008593:1103293:111622911162291117053825Clostridium novyi NT, complete genomeflagellar hook assembly protein FlgD3e-38159
NC_014328:1135854:113925511392551139974720Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative flagellar hook protein FlgD8e-29127
NC_021182:2883716:290370229037022904220519Clostridium pasteurianum BC1, complete genomeflagellar hook capping protein3e-25115
NC_010674:858397:864844864844865809966Clostridium botulinum B str. Eklund 17B, complete genomeflagellar hook assembly protein FlgD1e-22107
NC_010723:833870:843162843162844127966Clostridium botulinum E3 str. Alaska E43, complete genomeflagellar hook assembly protein FlgD1e-22107
NC_009617:4911595:4919690491969049207091020Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeflagellar hook capping protein2e-2099.4
NC_020291:4903981:4930617493061749318251209Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeflagellar hook protein FlgD2e-1995.9
NC_016584:4363382:438370943837094384500792Desulfosporosinus orientis DSM 765 chromosome, complete genomeflagellar hook capping protein1e-1170.5
NC_009633:2725128:273142827314282731832405Alkaliphilus metalliredigens QYMF chromosome, complete genomeflagellar hook capping protein1e-1067
NC_009012:574145:587106587106588077972Clostridium thermocellum ATCC 27405, complete genomeflagellar hook capping protein2e-1066.6
NC_009253:2615777:262294326229432623500558Desulfotomaculum reducens MI-1 chromosome, complete genomeflagellar hook capping protein2e-1066.2
NC_015172:1075592:108001510800151080806792Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeflagellar hook capping protein4e-1065.1
NC_011883:1478173:148163614816361482490855Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774,flagellar hook capping protein2e-0963.2
NC_014377:1060000:108066710806671081056390Thermosediminibacter oceani DSM 16646 chromosome, complete genomeflagellar hook capping protein7e-0961.2
NC_014652:628435:643647643647644141495Caldicellulosiruptor hydrothermalis 108 chromosome, completeflagellar hook capping protein1e-0860.5
NC_016894:2931213:294406829440682944487420Acetobacterium woodii DSM 1030 chromosome, complete genomeflagellar hook protein FlgD1e-0860.5
NC_000919:773784:793408793408793869462Treponema pallidum subsp. pallidum str. Nichols, complete genomeflagellar hook assembly protein2e-0859.7
NC_016843:775371:795179795179795640462Treponema pallidum subsp. pertenue str. Gauthier chromosome,flagellar basal body rod modification protein FlgD2e-0859.7
NC_016844:775334:795346795346795807462Treponema pallidum subsp. pallidum DAL-1 chromosome, completeflagellar basal body rod modification protein FlgD2e-0859.7
NC_016848:775822:795446795446795907462Treponema pallidum subsp. pertenue str. CDC2 chromosome, completeflagellar basal body rod modification protein FlgD2e-0859.7
NC_017268:775000:794658794658795119462Treponema pallidum subsp. pallidum str. Chicago chromosome,flagellar hook capping protein2e-0859.7
NC_021508:775264:794888794888795349462Treponema pallidum subsp. pallidum SS14, complete genomeflagellar basal body rod modification protein FlgD2e-0859.7
NC_015714:768500:788290788290788751462Treponema paraluiscuniculi Cuniculi A chromosome, complete genomeflagellar basal body rod modification protein FlgD2e-0859.7
NC_019978:625476:638719638719639129411Halobacteroides halobius DSM 5150, complete genomeflagellar hook capping protein1e-0757
NC_020134:586840:5998545998546008671014Clostridium stercorarium subsp. stercorarium DSM 8532, completeflagellar hook capping protein FlgD2e-0756.2
NC_008710:277207:296791296791297225435Borrelia turicatae 91E135, complete genomebasal-body rod modification protein FlgD4e-0755.5
NC_009664:533021:545381545381545908528Kineococcus radiotolerans SRS30216, complete genomeflagellar hook capping protein4e-0755.5
NC_009831:66518:782727827278937666Shewanella sediminis HAW-EB3, complete genomeflagellar hook capping protein7e-0754.7
NC_010673:291679:297500297500297934435Borrelia hermsii DAH, complete genomebasal-body rod modification protein FlgD6e-0754.7
NC_011728:269853:294153294153294596444Borrelia burgdorferi ZS7, complete genomeflagellar basal body rod modification protein6e-0754.7
NC_017238:272980:293892293892294335444Borrelia afzelii PKo chromosome, complete genomeflagellar hook assembly scaffolding protein6e-0754.7
NC_006156:271410:293552293552293995444Borrelia garinii PBi chromosome linear, complete sequenceflagellar hook assembly protein8e-0754.3
NC_018664:1663324:167729716772971677779483Clostridium acidurici 9a chromosome, complete genomeflagellar basal body rod modification protein FlgD1e-0653.5
NC_016751:1979201:198640119864011987069669Marinitoga piezophila KA3 chromosome, complete genomeflagellar hook capping protein2e-0653.1
NC_013223:685628:700295700295700978684Desulfohalobium retbaense DSM 5692, complete genomeflagellar hook capping protein2e-0653.1
NC_015424:2917817:292579129257912926531741Aeromonas veronii B565 chromosome, complete genomeflagellar hook capping protein2e-0652.8