Pre_GI: BLASTP Hits

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Query: NC_009698:2450606:2461072 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 2461072, End: 2461248, Length: 177

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2635892:266528526652852665461177Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein1e-27121
NC_009495:2606238:261661126166112616787177Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-27121
NC_010516:2594159:260465626046562604832177Clostridium botulinum B1 str. Okra, complete genomehypothetical protein1e-27121
NC_012658:2641446:267204226720422672218177Clostridium botulinum Ba4 str. 657 chromosome, complete genome2e-27120
NC_010520:2668702:267915226791522679328177Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein2e-27120
NC_012563:2761570:279098027909802791156177Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-27120
NC_010516:2567911:258649825864982586668171Clostridium botulinum B1 str. Okra, complete genomehypothetical protein2e-25114
NC_012563:2761570:277279627727962772966171Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-25114
NC_012658:2641446:265651226565122656682171Clostridium botulinum Ba4 str. 657 chromosome, complete genome2e-25114
NC_017297:2635892:264711726471172647287171Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein2e-25114
NC_012658:2641446:2674696267469626760001305Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative electron transport protein4e-2096.7
NC_012563:2761570:2793639279363927949431305Clostridium botulinum A2 str. Kyoto, complete genomeputative electron transport protein4e-2096.7
NC_009495:2606238:2619269261926926205731305Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeelectron transferring subunit of proline reductase4e-2096.7
NC_009697:2478261:2491386249138624926901305Clostridium botulinum A str. ATCC 19397 chromosome, completeelectron transport protein4e-2096.7
NC_009698:2450606:2463731246373124650351305Clostridium botulinum A str. Hall chromosome, complete genomeelectron transport protein4e-2096.7
NC_009699:2654672:2667794266779426690981305Clostridium botulinum F str. Langeland chromosome, complete genomeelectron transport protein4e-2096.7
NC_017297:2635892:2667942266794226692461305Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein4e-2096.7
NC_010516:2594159:2607315260731526086191305Clostridium botulinum B1 str. Okra, complete genomeputative electron transport protein4e-2096.7
NC_010520:2668702:2681811268181126831151305Clostridium botulinum A3 str. Loch Maree, complete genomeputative electron transport protein4e-2096.7
NC_009495:2606238:2623112262311226244221311Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeelectron transferring subunit of proline reductase2e-1891.3
NC_009697:2478261:2495229249522924965391311Clostridium botulinum A str. ATCC 19397 chromosome, completeelectron transport protein2e-1891.3
NC_009698:2450606:2467574246757424688841311Clostridium botulinum A str. Hall chromosome, complete genomeelectron transport protein2e-1891.3
NC_010520:2668702:2685656268565626869661311Clostridium botulinum A3 str. Loch Maree, complete genomeputative electron transport protein2e-1891.3
NC_012658:2641446:2678542267854226798521311Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative electron transport protein2e-1891.3
NC_012563:2761570:2797497279749727988071311Clostridium botulinum A2 str. Kyoto, complete genomeputative electron transport protein2e-1891.3
NC_010516:2594159:2611158261115826124681311Clostridium botulinum B1 str. Okra, complete genomeputative electron transport protein2e-1891.3
NC_009699:2654672:2671477267147726727871311Clostridium botulinum F str. Langeland chromosome, complete genomeelectron transport protein2e-1891.3
NC_017179:3621306:3635195363519536365081314Clostridium difficile BI1, complete genomeelectron transfer protein7e-1475.9
NC_013315:3613288:3627177362717736284901314Clostridium difficile CD196 chromosome, complete genomeelectron transfer protein7e-1475.9
NC_009089:3782000:3801552380155238028651314Clostridium difficile 630, complete genomeputative electron transfer protein7e-1475.9