Pre_GI: BLASTP Hits

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Query: NC_009698:1:14202 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 14202, End: 14277, Length: 76

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:490922:50205950205950213476Clostridium botulinum F str. 230613 chromosome, complete genometRNA-Ala8e-0752.4
NC_009495:482500:49068349068349075876Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala8e-0752.4
NC_009495:38000:56726567265680176Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala8e-0752.4
NC_009495:3735703:37512513751251375132676Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala8e-0752.4
NC_009495:1:14187141871426276Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala8e-0752.4
NC_010376:186510:19940519940519948076Finegoldia magna ATCC 29328, complete genometRNA-Ala8e-0752.4
NC_004557:2777291:27936662793666279374176Clostridium tetani E88, complete genometRNA-Ala8e-0752.4
NC_010376:606000:61336361336361343876Finegoldia magna ATCC 29328, complete genometRNA-Ala8e-0752.4
NC_004557:558500:56665756665756673276Clostridium tetani E88, complete genometRNA-Ala8e-0752.4
NC_020134:2295092:23108792310879231095476Clostridium stercorarium subsp. stercorarium DSM 8532, completetRNA-Ala8e-0752.4
NC_009697:1:14202142021427776Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala8e-0752.4
NC_009697:3711692:37272403727240372731576Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala8e-0752.4
NC_017297:1:14178141781425376Clostridium botulinum F str. 230613 chromosome, complete genometRNA-Ala8e-0752.4
NC_016627:4871875:48844744884474488454976Clostridium clariflavum DSM 19732 chromosome, complete genometRNA-Ala8e-0752.4
NC_016627:3815690:38274073827407382748276Clostridium clariflavum DSM 19732 chromosome, complete genometRNA-Ala8e-0752.4
NC_009699:490652:50178950178950186476Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala8e-0752.4
NC_009699:3839575:38540443854044385411976Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala8e-0752.4
NC_009699:1:14112141121418776Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala8e-0752.4
NC_009698:467500:47600847600847608376Clostridium botulinum A str. Hall chromosome, complete genometRNA-Ala8e-0752.4
NC_009698:3609881:36243493624349362442476Clostridium botulinum A str. Hall chromosome, complete genometRNA-Ala8e-0752.4
NC_009697:444801:45562045562045569576Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala8e-0752.4
NC_014410:403776:45069745069745077276Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,tRNA-Ala1e-0652
NC_014538:1975385:19885221988522198859776Thermoanaerobacter sp. X513 chromosome, complete genometRNA-Ala1e-0652
NC_003869:2143892:21549532154953215502876Thermoanaerobacter tengcongensis MB4, complete genometRNA-Ala1e-0652
NC_014209:1910109:19231381923138192321376Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,tRNA-Ala1e-0652
NC_015555:327562:37452137452137459676Thermoanaerobacterium xylanolyticum LX-11 chromosome, completetRNA-Ala1e-0652
NC_014964:388458:43553943553943561476Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completetRNA-Ala1e-0652
NC_018664:2459994:24717502471750247182576Clostridium acidurici 9a chromosome, complete genometRNA-Ala1e-0652
NC_014209:1487699:15058001505800150587576Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,tRNA-Ala1e-0652
NC_019970:336472:40582040582040589576Thermoanaerobacterium thermosaccharolyticum M0795, complete genometRNA-Ala1e-0652
NC_018664:3009166:30206993020699302077476Clostridium acidurici 9a chromosome, complete genometRNA-Ala1e-0652
NC_015958:2251619:22736442273644227371976Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genometRNA-Ala1e-0652
NC_010321:429720:44012344012344019876Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completetRNA-Ala1e-0652
NC_014624:2668157:26927942692794269286976Eubacterium limosum KIST612 chromosome, complete genometRNA-Ala1e-0652
NC_013520:1559000:15719701571970157204576Veillonella parvula DSM 2008, complete genometRNA-Ala1e-0651.6
NC_013520:571647:58100858100858108376Veillonella parvula DSM 2008, complete genometRNA-Ala1e-0651.6
NC_014720:1161841:11717531171753117182876Caldicellulosiruptor kronotskyensis 2002 chromosome, completetRNA-Ala4e-0650.1
NC_014652:2323598:23384042338404233847976Caldicellulosiruptor hydrothermalis 108 chromosome, completetRNA-Ala4e-0650.1
NC_014392:969498:99957599957599965076Caldicellulosiruptor obsidiansis OB47 chromosome, complete genometRNA-Ala4e-0650.1
NC_016894:3329562:33444843344484334455976Acetobacterium woodii DSM 1030 chromosome, complete genometRNA-Ala4e-0650.1
NC_016894:2809125:28195392819539281961476Acetobacterium woodii DSM 1030 chromosome, complete genometRNA-Ala4e-0650.1
NC_008346:36176:45777457774585276Syntrophomonas wolfei subsp. wolfei str. Goettingen, completetRNA-Ala4e-0650.1
NC_015519:1205049:12184631218463121853876Tepidanaerobacter sp. Re1 chromosome, complete genometRNA-Ala4e-0650.1
NC_014614:1090000:10985011098501109857676Clostridium sticklandii, complete genometRNA-Ala5e-0650.1
NC_014614:2500301:25138562513856251393176Clostridium sticklandii, complete genometRNA-Ala5e-0650.1
NC_014614:554949:57155157155157162676Clostridium sticklandii, complete genometRNA-Ala5e-0650.1
NC_014657:291567:30192330192330199876Caldicellulosiruptor owensensis OL chromosome, complete genometRNA-Ala4e-0650.1
NC_014720:2420455:24461052446105244618076Caldicellulosiruptor kronotskyensis 2002 chromosome, completetRNA-Ala4e-0650.1
NC_014392:412916:42697342697342704876Caldicellulosiruptor obsidiansis OB47 chromosome, complete genometRNA-Ala4e-0650.1
NC_015949:1180755:11914041191404119147976Caldicellulosiruptor lactoaceticus 6A chromosome, complete genometRNA-Ala4e-0650.1
NC_014209:1363151:13748051374805137488076Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,tRNA-Ala4e-0650.1
NC_009437:2367842:23784542378454237852976Caldicellulosiruptor saccharolyticus DSM 8903, complete genometRNA-Ala4e-0650.1
NC_012034:1783912:17946861794686179476176Anaerocellum thermophilum DSM 6725, complete genometRNA-Ala4e-0650.1
NC_009437:283382:28585928585928593476Caldicellulosiruptor saccharolyticus DSM 8903, complete genometRNA-Ala4e-0650.1
NC_014652:1032711:10643831064383106445876Caldicellulosiruptor hydrothermalis 108 chromosome, completetRNA-Ala4e-0650.1
NC_014657:1518721:15298411529841152991676Caldicellulosiruptor owensensis OL chromosome, complete genometRNA-Ala4e-0650.1
NC_012034:438000:45174345174345181876Anaerocellum thermophilum DSM 6725, complete genometRNA-Ala4e-0650.1
NC_014721:373607:38423038423038430576Caldicellulosiruptor kristjanssonii 177R1B chromosome, completetRNA-Ala4e-0650.1
NC_014721:1777644:17883081788308178838376Caldicellulosiruptor kristjanssonii 177R1B chromosome, completetRNA-Ala4e-0650.1
NC_009922:2590317:26083132608313260838876Alkaliphilus oremlandii OhILAs, complete genometRNA-Ala6e-0649.7
NC_009922:1917271:19276921927692192776776Alkaliphilus oremlandii OhILAs, complete genometRNA-Ala6e-0649.7
NC_009922:42696:64740647406481576Alkaliphilus oremlandii OhILAs, complete genometRNA-Ala6e-0649.7
NC_008262:2649289:26755392675539267561476Clostridium perfringens SM101, complete genometRNA-Ala1e-0548.9
NC_008261:2770468:27815992781599278167476Clostridium perfringens ATCC 13124, complete genometRNA-Ala1e-0548.9
NC_008262:67711:90758907589083376Clostridium perfringens SM101, complete genometRNA-Ala1e-0548.9
NC_008261:1:15074150741514976Clostridium perfringens ATCC 13124, complete genometRNA-Ala1e-0548.9
NC_008262:2433979:24450972445097244517276Clostridium perfringens SM101, complete genometRNA-Ala1e-0548.9