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Query: NC_009648:3803622:3846436 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Start: 3846436, End: 3847020, Length: 585

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003366:1122654:112945211294521130024573Clostridium perfringens str. 13, complete genomecoenzyme B12-dependent glycerol dehydrogenase medium subunit4e-61234
NC_008261:1332864:134032213403221340888567Clostridium perfringens ATCC 13124, complete genomecoenzyme B12-dependent glycerol dehydratase, medium subunit7e-61233
NC_008262:1139500:114693411469341147500567Clostridium perfringens SM101, complete genomeglycerol dehydratase, beta subunit1e-60232
NC_014632:1404000:141397914139791414542564Ilyobacter polytropus DSM 2926 chromosome, complete genomeglycerol dehydratase, cobalamin-dependent subunit beta3e-59228
NC_010723:2082750:209402920940292094604576Clostridium botulinum E3 str. Alaska E43, complete genomepropanediol utilization: dehydratase, medium subunit2e-58224
NC_010674:2185704:219916421991642199739576Clostridium botulinum B str. Eklund 17B, complete genomepropanediol utilization: dehydratase, medium subunit5e-58223
NC_013766:1202713:120843412084341209093660Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein4e-55213
NC_012488:1159463:116648111664811167140660Listeria monocytogenes Clip81459, complete genomediol dehydrase (diol dehydratase) gamma subunit1e-54212
NC_014633:442755:453864453864454517654Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencedehydratase medium subunit2e-53208
NC_017243:1813158:183021718302171830903687Brachyspira intermedia PWS/A chromosome, complete genomedehydratase medium subunit2e-53208
NC_019970:2080419:209095120909512091607657Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeDehydratase medium subunit7e-53206
NC_013517:1055854:111742611174261118100675Sebaldella termitidis ATCC 33386, complete genomedehydratase medium subunit8e-53206
NC_010320:1949852:196096919609691961658690Thermoanaerobacter sp. X514 chromosome, complete genomedehydratase, medium subunit4e-45180
NC_014538:985339:992686992686993375690Thermoanaerobacter sp. X513 chromosome, complete genomedehydratase medium subunit4e-45180
NC_008497:1575884:157642415764241577143720Lactobacillus brevis ATCC 367, complete genomeDiol Dehydratase medium subunit9e-43172
NC_014654:1113116:112032411203241120980657Halanaerobium sp. 'sapolanicus' chromosome, complete genomedehydratase medium subunit9e-43172