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Query: NC_009648:3803622:3846008 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Start: 3846008, End: 3846433, Length: 426

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010674:2185704:219872021987202199142423Clostridium botulinum B str. Eklund 17B, complete genomecoenzyme B12-dependent glycerol dehydratase, small subunit2e-47187
NC_010723:2082750:209358520935852094007423Clostridium botulinum E3 str. Alaska E43, complete genomecoenzyme B12-dependent glycerol dehydratase, small subunit2e-47187
NC_008262:1139500:114752011475201147945426Clostridium perfringens SM101, complete genomeglycerol dehydrase, gamma subunit4e-46183
NC_003366:1122654:113004411300441130469426Clostridium perfringens str. 13, complete genomecoenzyme B12-dependent glycerol dehydrogenase small subunit4e-46182
NC_008261:1332864:134090813409081341333426Clostridium perfringens ATCC 13124, complete genomecoenzyme B12-dependent glycerol dehydratase, small subunit4e-46182
NC_013517:1055854:111811411181141118614501Sebaldella termitidis ATCC 33386, complete genomedehydratase small subunit2e-42170
NC_013766:1202713:120911012091101209622513Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein5e-41166
NC_012488:1159463:116715711671571167669513Listeria monocytogenes Clip81459, complete genomediol dehydrase (diol dehydratase) gamma subunit (pddC)6e-41166
NC_017243:1813158:182969218296921830171480Brachyspira intermedia PWS/A chromosome, complete genomeglycerol dehydrase1e-39161
NC_014632:1404000:141353514135351413966432Ilyobacter polytropus DSM 2926 chromosome, complete genomeglycerol dehydratase, cobalamin-dependent subunit gamma4e-38156
NC_014633:442755:454556454556455038483Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencedehydratase small subunit2e-37154
NC_019970:2080419:209043520904352090938504Thermoanaerobacterium thermosaccharolyticum M0795, complete genomepropanediol dehydratase, small subunit1e-36151
NC_010320:1949852:196045519604551960979525Thermoanaerobacter sp. X514 chromosome, complete genomedehydratase, small subunit1e-35148
NC_014538:985339:993365993365993889525Thermoanaerobacter sp. X513 chromosome, complete genomedehydratase small subunit1e-35148
NC_008497:1575884:157588415758841576411528Lactobacillus brevis ATCC 367, complete genomePropanediol dehydratase, small subunit8e-35145
NC_011837:830436:846147846147846695549Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-34145
NC_009706:830461:846190846190846720531Clostridium kluyveri DSM 555 chromosome, complete genomeprotein DhaC1e-34145
NC_014654:1113116:112100611210061121524519Halanaerobium sp. 'sapolanicus' chromosome, complete genomedehydratase small subunit6e-33139