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Query: NC_009567:904922:905817 Haemophilus influenzae PittGG chromosome, complete genome

Start: 905817, End: 906023, Length: 207

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Strain PittGG is a non-typeable Haemophilus influenzae (NTHi) isolate recovered by Dr. Robert Wadowsky from the external ear discharge of a spontaneously perforated tympanic membrane of a child in Pittsburgh, USA who had been diagnosed with otorrhea. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007146:1405459:142877714287771428983207Haemophilus influenzae 86-028NP, complete genomehypothetical protein2e-2097.8
NC_009655:1357486:136976213697621369965204Actinobacillus succinogenes 130Z chromosome, complete genomehypothetical protein8e-1682.4
NC_011740:2769961:278658027865802786813234Escherichia fergusonii ATCC 35469, complete genomerepresror Cro2e-1064.7
NC_011415:600375:617392617392617619228Escherichia coli SE11 chromosome, complete genomehypothetical protein2e-1064.7
NC_020063:2565605:258356725835672583794228Enterobacteriaceae bacterium strain FGI 57, complete genomehypothetical protein1e-0961.6
NC_016860:364981:380070380070380285216Salmonella enterica subsp. enterica serovar Typhimurium strphage transcriptional regulator4e-0856.6
NC_013361:3287671:329475332947533294977225Escherichia coli O26:H11 str. 11368 chromosome, complete genomeantirepressor protein Cro7e-0649.3