Pre_GI: BLASTN Hits

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Query: NC_009565:2806000 Mycobacterium tuberculosis F11, complete genome

Start: 2806000, End: 2828229, Length: 22230

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (genotype F11) represents the largest portion of isolates recovered from tuberculosis patients during a TB epidemic in the Western Cape of South Africa. Causative agent of tuberculosis. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009525:28029872802987282687923893Mycobacterium tuberculosis H37Ra, complete genome018080BLASTN svgBLASTP svg
NC_000962:27910192791019281491123893Mycobacterium tuberculosis H37Rv, complete genome018070BLASTN svgBLASTP svg
NC_002755:27880002788000281039922400Mycobacterium tuberculosis CDC1551, complete genome018070BLASTN svgBLASTP svg
NC_012207:27475992747599277148023882Mycobacterium bovis BCG str. Tokyo 172, complete genome018050BLASTN svgBLASTP svg
NC_008769:27548282754828277870723880Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome018050BLASTN svgBLASTP svg
NC_002945:27578212757821278170823888Mycobacterium bovis AF2122/97, complete genome018050BLASTN svgBLASTP svg
NC_015848:28591452859145288297223828Mycobacterium canettii CIPT 140010059, complete genome017920BLASTN svgBLASTP svg
NC_019950:28306822830682285444023759Mycobacterium canettii CIPT 140060008 complete genome017710BLASTN svgBLASTP svg
NC_011896:14622581462258148837626119Mycobacterium leprae Br4923, complete genome2e-38168BLASTN svgBLASTP svg
NC_002677:14622331462233148835226120Mycobacterium leprae TN, complete genome2e-38168BLASTN svgBLASTP svg
NC_010730:952574*95257497119218619Sulfurihydrogenibium sp. YO3AOP1, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_014550:2091797*2091797212997638180Arthrobacter arilaitensis Re117, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_012440:1841315*1841315186760426290Persephonella marina EX-H1, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010612:61131556113155613265419500Mycobacterium marinum M, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_013093:1213908*1213908124337529468Actinosynnema mirum DSM 43827, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_013851:2317091*2317091233893321843Allochromatium vinosum DSM 180 chromosome, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_020133:57106615710661573224421584Mycobacterium liflandii 128FXT, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_006087:1334500*1334500136229227793Leifsonia xyli subsp. xyli str. CTCB07, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014216:2538500*2538500256387025371Desulfurivibrio alkaliphilus AHT2 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_011138:3182807*3182807321165528849Alteromonas macleodii 'Deep ecotype', complete genome4e-0867.9BLASTN svgBLASTP svg
NC_009565:16297801629780165615326374Mycobacterium tuberculosis F11, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_002945:16217651621765164826226498Mycobacterium bovis AF2122/97, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_010612:22157242215724224185126128Mycobacterium marinum M, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_015557:114648*11464815148336836Hydrogenobaculum sp. 3684 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_015587:114684*11468415151936836Hydrogenobaculum sp. SHO chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_020133:2144752*2144752217059925848Mycobacterium liflandii 128FXT, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_020411:114683*11468315151836836Hydrogenobaculum sp. HO, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_020260:2725201*2725201275882333623Cronobacter sakazakii Sp291, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_020133:90200090200092552523526Mycobacterium liflandii 128FXT, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_020064:1150982*1150982117040619425Serratia marcescens FGI94, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_013282:12009931200993124927948287Cronobacter turicensis, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_010612:95778695778698186224077Mycobacterium marinum M, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009525:39335673933567395892925363Mycobacterium tuberculosis H37Ra, complete genome3e-0661.9BLASTN svgBLASTP svg