Pre_GI: BLASTP Hits

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Query: NC_009495:3688138:3712426 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 3712426, End: 3712665, Length: 240

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3553365:358552435855243585763240Clostridium botulinum A str. Hall chromosome, complete genomeribosomal protein L7Ae family protein2e-37154
NC_012563:3956500:398034139803413980583243Clostridium botulinum A2 str. Kyoto, complete genomeribosomal protein L7Ae family protein6e-37152
NC_010516:3759136:378342337834233783665243Clostridium botulinum B1 str. Okra, complete genomeribosomal protein L7Ae family protein6e-37152
NC_010520:3788702:381299638129963813238243Clostridium botulinum A3 str. Loch Maree, complete genomeribosomal protein L7Ae family protein6e-37152
NC_009699:3790917:381520438152043815446243Clostridium botulinum F str. Langeland chromosome, complete genomeribosomal protein L7Ae family protein6e-37152
NC_012658:3778822:380312338031233803365243Clostridium botulinum Ba4 str. 657 chromosome, complete genomeribosomal protein L7Ae family protein6e-37152
NC_017297:3787191:381381838138183814060243Clostridium botulinum F str. 230613 chromosome, complete genomeribosomal protein L7Ae family protein6e-37152
NC_014328:4387303:445088944508894451131243Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeribosomal protein L7Ae-like protein5e-24109
NC_021182:4557608:458146345814634581702240Clostridium pasteurianum BC1, complete genomeribosomal protein HS6-type (S12/L30/L7a)5e-1992.8
NC_014393:4482896:450747945074794507715237Clostridium cellulovorans 743B chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd453e-1890.5
NC_008261:2957354:298044429804442980683240Clostridium perfringens ATCC 13124, complete genomeribosomal protein L7AE family5e-1786.3
NC_003366:2731995:275780027578002758066267Clostridium perfringens str. 13, complete genomeribosomal protein L7AE family5e-1786.3
NC_008262:2598920:262399526239952624234240Clostridium perfringens SM101, complete genomeribosomal protein L7AE family5e-1786.3
NC_003030:3251941:327488432748843275123240Clostridium acetobutylicum ATCC 824, complete genomeRibosomal protein HS6-type5e-1786.3
NC_015687:3252233:327651132765113276750240Clostridium acetobutylicum DSM 1731 chromosome, complete genomeribosomal protein HS6-type5e-1786.3
NC_017295:3250451:327414132741413274380240Clostridium acetobutylicum EA 2018 chromosome, complete genomeRibosomal protein HS6-type5e-1786.3
NC_008593:196257:230467230467230709243Clostridium novyi NT, complete genomeribosomal protein L7AE family, putative2e-1684.3
NC_009633:4563877:458323445832344583476243Alkaliphilus metalliredigens QYMF chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd455e-1682.8
NC_015958:2251619:229937722993772299631255Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd454e-1580.1
NC_014964:388458:409558409558409812255Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete50S ribosomal protein L7Ae/L30e/S12e/Gadd454e-1580.1
NC_010321:393000:414142414142414396255Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeputative L7Ae-like ribosomal protein4e-1580.1
NC_014538:1998180:201424820142482014502255Thermoanaerobacter sp. X513 chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd454e-1580.1
NC_010320:881351:900082900082900336255Thermoanaerobacter sp. X514 chromosome, complete genomeputative L7Ae-like ribosomal protein4e-1580.1
NC_014410:403776:424498424498424743246Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,ribosomal protein L7Ae/L30e/S12e/Gadd457e-1579.3
NC_019970:336472:379618379618379863246Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeribosomal protein HS6-type (S12/L30/L7a)1e-1478.6
NC_016627:762000:771596771596771838243Clostridium clariflavum DSM 19732 chromosome, complete genomeribosomal protein HS6-type (S12/L30/L7a)3e-1477
NC_011899:124500:131728131728131976249Halothermothrix orenii H 168, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd454e-1476.6
NC_018664:2357882:238005723800572380299243Clostridium acidurici 9a chromosome, complete genomeribosomal protein, L7Ae family5e-1476.6
NC_015555:327562:348323348323348568246Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeribosomal protein L7Ae/L30e/S12e/Gadd457e-1475.9
NC_014377:112992:123107123107123355249Thermosediminibacter oceani DSM 16646 chromosome, complete genomeLSU ribosomal protein L7AE3e-1373.9
NC_009922:542500:554042554042554284243Alkaliphilus oremlandii OhILAs, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd453e-1373.6
NC_015520:2280643:229201922920192292282264Mahella australiensis 50-1 BON chromosome, complete genome50S ribosomal protein L7AE5e-1373.2
NC_009012:3204696:321884432188443219083240Clostridium thermocellum ATCC 27405, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd455e-1373.2
NC_018515:223164:233365233365233658294Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeribosomal protein HS6-type (S12/L30/L7a)5e-1373.2
NC_014152:305955:312880312880313131252Thermincola sp. JR, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd456e-1372.8
NC_014829:133305:144131144131144379249Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd457e-1372.8
NC_015519:197836:209030209030209278249Tepidanaerobacter sp. Re1 chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd458e-1372.4
NC_011898:351792:365219365219365461243Clostridium cellulolyticum H10, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd458e-1372.4
NC_020134:2832857:284840028484002848645246Clostridium stercorarium subsp. stercorarium DSM 8532, completeribosomal protein HS6-type1e-1271.6
NC_014654:2101500:211748421174842117726243Halanaerobium sp. 'sapolanicus' chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-1270.9
NC_013216:293571:307995307995308243249Desulfotomaculum acetoxidans DSM 771, complete genomeputative ribosomal protein L7Ae-like protein4e-1270.1
NC_014652:1898969:190926919092691909523255Caldicellulosiruptor hydrothermalis 108 chromosome, completeribosomal protein l7ae/l30e/s12e/gadd455e-1269.7
NC_015949:1363053:137248913724891372743255Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome50S ribosomal protein L7Ae/L30e/S12e/Gadd451e-1168.6
NC_013385:1504650:152124515212451521496252Ammonifex degensii KC4, complete genomehypothetical protein1e-1168.6
NC_014657:742739:754784754784755038255Caldicellulosiruptor owensensis OL chromosome, complete genomeribosomal protein l7ae/l30e/s12e/gadd451e-1168.6
NC_013921:1977444:201969420196942019948255Thermoanaerobacter italicus Ab9 chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-1168.2
NC_012034:893000:903022903022903276255Anaerocellum thermophilum DSM 6725, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-1167.8
NC_014721:1953708:196314419631441963398255Caldicellulosiruptor kristjanssonii 177R1B chromosome, completeribosomal protein l7ae/l30e/s12e/gadd452e-1167.8
NC_014392:848195:860235860235860489255Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-1167.4
NC_009454:316000:323912323912324163252Pelotomaculum thermopropionicum SI, complete genomeribosomal protein HS6-type7e-1166.2
NC_015275:3846260:386666938666693866911243Clostridium lentocellum DSM 5427 chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd454e-1063.5
NC_007503:2063451:207808920780892078352264Carboxydothermus hydrogenoformans Z-2901, complete genomeribosomal protein L7ae family protein2e-0961.6
NC_013406:6422000:643903664390366439287252Paenibacillus sp. Y412MC10 chromosome, complete genomeputative ribosomal protein L7Ae-like protein5e-0960.1
NC_010718:193231:215009215009215257249Natranaerobius thermophilus JW/NM-WN-LF, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd453e-0857
NC_014171:109280:122566122566122814249Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein6e-0856.2
NC_017208:108134:124616124616124864249Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein3e-0753.9
NC_016148:678175:692788692788693081294Thermovirga lienii DSM 17291 chromosome, complete genomeribosomal protein L7AE family protein1e-0548.9