Pre_GI: BLASTP Hits

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Query: NC_009495:3502000:3502001 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 3502001, End: 3503323, Length: 1323

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3359766:3375097337509733764191323Clostridium botulinum A str. Hall chromosome, complete genomebranched-chain amino acid transport system II carrier protein0744
NC_009697:3463736:3477989347798934793111323Clostridium botulinum A str. ATCC 19397 chromosome, completebranched-chain amino acid transport system II carrier protein0744
NC_010516:3545017:3562910356291035642321323Clostridium botulinum B1 str. Okra, complete genomebranched-chain amino acid transport system II carrier protein0743
NC_017297:3594000:3594250359425035955721323Clostridium botulinum F str. 230613 chromosome, complete genomebranched-chain amino acid transport system II carrier protein0740
NC_009699:3581376:3595634359563435969561323Clostridium botulinum F str. Langeland chromosome, complete genomebranched-chain amino acid transport system II carrier protein0740
NC_012563:3729817:3744057374405737453971341Clostridium botulinum A2 str. Kyoto, complete genomebranched-chain amino acid transport system II carrier protein0730
NC_010520:3580000:3580008358000835811981191Clostridium botulinum A3 str. Loch Maree, complete genomebranched-chain amino acid transport system II carrier protein0636
NC_008593:1631438:1649289164928916505961308Clostridium novyi NT, complete genomebranched-chain amino acid transport system II carrier protein6e-78291
NC_015425:1867620:1888467188846718898191353Clostridium botulinum BKT015925 chromosome, complete genomebranched-chain amino acid transport system II carrier protein3e-72273
NC_014377:149288:1539801539801552811302Thermosediminibacter oceani DSM 16646 chromosome, complete genomebranched-chain amino acid transport system II carrier protein9e-66251
NC_014377:149288:1524711524711537721302Thermosediminibacter oceani DSM 16646 chromosome, complete genomebranched-chain amino acid transport system II carrier protein1e-63244
NC_015633:2565753:2610211261021126115241314Vibrio anguillarum 775 chromosome chromosome I, complete sequenceBranched chain amino acid transport4e-40166
NC_003454:677699:6894806894806907541275Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeBranched-chain amino acid transport system carrier protein7e-38158
NC_019896:1483073:1498446149844614997681323Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeBranched-chain amino acid transport system carrier protein BrnQ1e-36154
NC_020244:2509000:2542390254239025437121323Bacillus subtilis XF-1, complete genomelow-affinity branched-chain amino acid transporter2e-36154
NC_012779:2928000:2928202292820229295721371Edwardsiella ictaluri 93-146, complete genomebranched-chain amino acid transport system II carrier protein, putative4e-32139
NC_007622:271673:2930092930092943161308Staphylococcus aureus RF122, complete genomeprobable branched-chain amino acid transport system II carrier protein2e-31137
NC_015167:1666000:1689690168969016909791290Cellulophaga lytica DSM 7489 chromosome, complete genomebranched-chain amino acid transport system II carrier protein2e-30133
NC_004193:375416:4475254475254488771353Oceanobacillus iheyensis HTE831, complete genomebranched-chain amino acid transporter4e-30132
NC_016052:2201211:2203730220373022050791350Tetragenococcus halophilus NBRC 12172, complete genomebranched-chain amino acid transport system carrier protein3e-28126
NC_012913:1867276:1885944188594418872721329Aggregatibacter aphrophilus NJ8700, complete genomebranched-chain amino acid transport system II carrier protein2e-25117
NC_014554:337268:3548503548503562261377Lactobacillus plantarum subsp. plantarum ST-III chromosome,LIVCS family branched chain amino acid:cation symporter8e-24112
NC_004567:343500:3623983623983637741377Lactobacillus plantarum WCFS1, complete genomebranched-chain amino acid transport protein8e-24112
NC_015428:193817:2055082055082069111404Lactobacillus buchneri NRRL B-30929 chromosome, complete genomebranched-chain amino acid transport system II carrier protein1e-23111
NC_016789:1805503:1819265181926518204731209Corynebacterium diphtheriae PW8 chromosome, complete genome1e-22107
NC_016799:1787687:1804265180426518055691305Corynebacterium diphtheriae 31A chromosome, complete genomebranched-chain amino acid uptake carrier3e-22106
NC_002935:1763886:1779545177954517808491305Corynebacterium diphtheriae NCTC 13129, complete genomebranched-chain amino acid ABC transport system membrane protein6e-22105
NC_016783:1758319:1772095177209517733991305Corynebacterium diphtheriae INCA 402 chromosome, complete genomebranched-chain amino acid uptake carrier6e-22105
NC_016801:1782401:1796164179616417974681305Corynebacterium diphtheriae C7 (beta) chromosome, complete genomebranched-chain amino acid uptake carrier6e-22105
NC_016787:1726978:1740743174074317420471305Corynebacterium diphtheriae HC03 chromosome, complete genomebranched-chain amino acid uptake carrier6e-22105
NC_016788:1730458:1744223174422317455271305Corynebacterium diphtheriae HC04 chromosome, complete genomebranched-chain amino acid uptake carrier6e-22105
NC_016790:1702856:1716620171662017179241305Corynebacterium diphtheriae VA01 chromosome, complete genomebranched-chain amino acid uptake carrier6e-22105
NC_016802:1709840:1728807172880717301111305Corynebacterium diphtheriae HC02 chromosome, complete genomebranched-chain amino acid uptake carrier5e-22105
NC_011134:533679:5521095521095534521344Streptococcus equi subsp. zooepidemicus str. MGCS10565, completebranched-chain amino acid transport system carrier protein BraB1e-21104
NC_016628:133841:1338411338411351421302Vibrio furnissii NCTC 11218 chromosome 2, complete sequencebranched-chain amino acid transport system II carrier protein1e-21104
NC_016782:1745374:1764369176436917656731305Corynebacterium diphtheriae 241 chromosome, complete genomebranched-chain amino acid uptake carrier2e-21103
NC_016786:1751204:1764969176496917662731305Corynebacterium diphtheriae HC01 chromosome, complete genomebranched-chain amino acid uptake carrier2e-21103
NC_012470:1635516:1639580163958016409291350Streptococcus equi subsp. zooepidemicus, complete genomebranched-chain amino acid transport system carrier protein2e-20100
NC_004461:205068:2075332075332088911359Staphylococcus epidermidis ATCC 12228, complete genomebranched-chain amino acid transport system carrier protein2e-1997.4
NC_015516:131564:155955155955156614660Melissococcus plutonius ATCC 35311, complete genomebranched-chain amino acid transport system carrier protein2e-1480.5