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Query: NC_009495:280000:300431 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 300431, End: 300943, Length: 513

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009697:275919:293431293431293943513Clostridium botulinum A str. ATCC 19397 chromosome, completeacetyltransferase8e-95345
NC_009707:1811650:183093618309361831466531Campylobacter jejuni subsp. doylei 269.97 chromosome, completeacetyltransferase1e-1065.9
NC_014802:1631483:165079616507961651326531Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, completeacetyltransferase, GNAT family2e-1065.1
NC_008787:1582110:160257216025721603102531Campylobacter jejuni subsp. jejuni 81-176, complete genomeacetyltransferase, GNAT family2e-1065.1
NC_017280:1584961:160569816056981606282585Campylobacter jejuni subsp. jejuni M1 chromosome, complete genomeGNAT family acetyltransferase5e-1063.9
NC_002163:1607360:162680716268071627337531Campylobacter jejuni subsp. jejuni NCTC 11168, complete genomeputative acetyltransferase5e-1063.9
NC_017279:1603916:162420116242011624731531Campylobacter jejuni subsp. jejuni IA3902 chromosome, completeGNAT family acetyltransferase5e-1063.9
NC_003912:1742370:176381717638171764347531Campylobacter jejuni RM1221, complete genomeacetyltransferase, GNAT family5e-1063.9
NC_017281:1645903:166735016673501667880531Campylobacter jejuni subsp. jejuni S3 chromosome, complete genomePutative acetyltransferase5e-1063.9
NC_013406:2866000:288084828808482881357510Paenibacillus sp. Y412MC10 chromosome, complete genomeGCN5-like N-acetyltransferase3e-0961.2
NC_006856:26438:277462774628246501Salmonella enterica subsp. enterica serovar Choleraesuis strSulI3'1e-0859.3
NC_009140:121107:134928134928135428501Salmonella enterica enterica sv Newport str. SL254, completehypothetical protein1e-0859.3
NC_009349:78000:895328953290032501Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, completeputative acetyltransferase1e-0859.3
NC_011586:268927:284713284713285213501Acinetobacter baumannii AB0057 chromosome, complete genomehypothetical protein1e-0859.3
NC_011586:268927:316572316572317072501Acinetobacter baumannii AB0057 chromosome, complete genomeGNAT family acetyltransferase1e-0859.3
NC_016860:4055117:407722440772244077724501Salmonella enterica subsp. enterica serovar Typhimurium strputative acetyltransferase1e-0859.3
NC_017171:1331794:134698613469861347486501Acinetobacter baumannii MDR-ZJ06 chromosome, complete genomehypothetical protein1e-0859.3
NC_017387:247462:269087269087269587501Acinetobacter baumannii TCDC-AB0715 chromosome, complete genomehypothetical protein1e-0859.3
NC_017387:247462:279921279921280421501Acinetobacter baumannii TCDC-AB0715 chromosome, complete genomehypothetical protein1e-0859.3
NC_014836:2919508:870387039266564Desulfurispirillum indicum S5 chromosome, complete genomeGCN5-like N-acetyltransferase1e-0859.3
NC_004193:375416:386229386229386747519Oceanobacillus iheyensis HTE831, complete genomehypothetical protein5e-0753.9
NC_020272:3245834:324878032487803249313534Bacillus amyloliquefaciens IT-45, complete genomeGNAT family acetyltransferase3e-0650.8