Some Help

Query: NC_009495:2056546:2060717 Clostridium botulinum A str. ATCC 3502 chromosome, complete genome

Start: 2060717, End: 2060944, Length: 228

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well-studied Hall strain that produces type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:1985404:198957519895751989802228Clostridium botulinum A str. Hall chromosome, complete genomemolybdopterin converting factor subunit 17e-36149
NC_009697:1985187:198935819893581989585228Clostridium botulinum A str. ATCC 19397 chromosome, completemolybdopterin converting factor subunit 17e-36149
NC_012563:2203037:220720822072082207435228Clostridium botulinum A2 str. Kyoto, complete genomemolybdopterin converting factor subunit 17e-36149
NC_010516:2064027:206865320686532068880228Clostridium botulinum B1 str. Okra, complete genomemolybdopterin converting factor subunit 12e-35147
NC_010520:2171584:217807121780712178298228Clostridium botulinum A3 str. Loch Maree, complete genomemolybdopterin converting factor subunit 14e-35146
NC_017297:2114222:211884721188472119074228Clostridium botulinum F str. 230613 chromosome, complete genomemolybdopterin converting factor subunit 11e-34144
NC_009699:2116500:211874621187462118973228Clostridium botulinum F str. Langeland chromosome, complete genomemolybdopterin converting factor subunit 11e-34144
NC_014972:2371647:239273023927302392954225Desulfobulbus propionicus DSM 2032 chromosome, complete genomethiamine protein1e-0858.2