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Query: NC_009381:627685:634440 Yersinia pestis Pestoides F chromosome, complete genome

Start: 634440, End: 634970, Length: 531

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:3661601:367559136755913676166576Yersinia pestis KIM, complete genomehypothetical protein1e-86318
NC_017265:854492:861248861248861778531Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,2e-86317
NC_017168:50391:572315723157761531Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-86317
NC_017160:945176:951932951932952462531Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-86317
NC_017154:941065:949958949958950488531Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-86317
NC_014029:1001000:100781310078131008343531Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-86317
NC_008149:3529428:354341735434173543947531Yersinia pestis Nepal516, complete genomehypothetical protein2e-86317
NC_008150:361224:370099370099370629531Yersinia pestis Antiqua, complete genomehypothetical protein2e-86317
NC_009708:986918:993873993873994607735Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein6e-76282
NC_006155:3779381:379313237931323793890759Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-75281
NC_010465:933488:940337940337941071735Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein2e-75281
NC_010634:3692321:370611437061143706848735Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-75281
NC_012779:261438:281199281199281927729Edwardsiella ictaluri 93-146, complete genomehypothetical protein2e-47188
NC_016818:3851542:385154238515423852276735Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completehypothetical protein1e-46185
NC_013508:275081:298170298170298901732Edwardsiella tarda EIB202, complete genomehypothetical protein2e-46184
NC_020418:1397112:142313314231331423861729Morganella morganii subsp. morganii KT, complete genomePutative protein YggN2e-39161