Pre_GI: BLASTP Hits

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Query: NC_009381:588137:597610 Yersinia pestis Pestoides F chromosome, complete genome

Start: 597610, End: 597891, Length: 282

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:905783:915132915132915554423Yersinia pestis D182038 chromosome, complete genomeCAAX amino terminal protease family protein3e-46183
NC_017154:902739:913023913023913445423Yersinia pestis D106004 chromosome, complete genomeCAAX amino terminal protease family protein3e-46183
NC_014029:961522:970871970871971293423Yersinia pestis Z176003 chromosome, complete genomeCAAX amino terminal protease family protein3e-46183
NC_010159:172469:191226191226191648423Yersinia pestis Angola, complete genomeCAAX amino terminal protease family protein3e-46183
NC_008149:3556999:358551735855173586167651Yersinia pestis Nepal516, complete genomemembrane protein5e-46182
NC_010465:893921:903021903021903671651Yersinia pseudotuberculosis YPIII, complete genomeAbortive infection protein5e-46182
NC_003143:1059580:108953310895331090183651Yersinia pestis CO92, complete genomehypothetical protein5e-46182
NC_006155:3805640:383562238356223836272651Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein5e-46182
NC_010634:3720214:374869437486943749344651Yersinia pseudotuberculosis PB1/+, complete genomeabortive infection protein5e-46182
NC_008150:317903:327958327958328608651Yersinia pestis Antiqua, complete genomehypothetical protein5e-46182
NC_004088:3689000:371764037176403718290651Yersinia pestis KIM, complete genomehypothetical protein5e-46182
NC_005810:3917254:392905539290553929705651Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein5e-46182
NC_009708:874770:883884883884884534651Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeCAAX amino terminal protease family protein5e-46182
NC_017168:3286:150911509115741651Yersinia pestis A1122 chromosome, complete genomehypothetical protein5e-46182
NC_017265:809943:819059819059819709651Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein5e-46182
NC_012880:2871480:289277428927742893427654Dickeya dadantii Ech703, complete genomeAbortive infection protein2e-23107
NC_004431:279868:297875297875298303429Escherichia coli CFT073, complete genomehypothetical protein5e-1063.2
NC_013592:2703327:271653127165312717184654Dickeya dadantii Ech586, complete genomeAbortive infection protein1e-0961.6
NC_008253:296500:306641306641307327687Escherichia coli 536, complete genomehypothetical protein3e-0960.5
NC_004431:1166568:118357211835721184258687Escherichia coli CFT073, complete genomehypothetical protein6e-0959.7
NC_011749:34056:494324943250085654Escherichia coli UMN026 plasmid p1ESCUM, complete sequencehypothetical protein7e-0855.8