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Query: NC_009378:62215:88951 Yersinia pestis Pestoides F plasmid MT, complete sequence

Start: 88951, End: 89700, Length: 750

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014305:126029:150567150567151364798Erwinia billingiae Eb661 plasmid pEB170, complete sequenceconjugal pilus assembly protein2e-58225
NC_010699:1:157771577716565789Erwinia tasmaniensis plasmid pET45, complete sequenceTraF protein2e-50198
NC_009998:62000:540154016276876Shewanella baltica OS195 plasmid pS19501, complete sequencetype-F conjugative transfer system pilin assembly protein TraF6e-25114
NC_007794:2304768:2304768230476823058831116Novosphingobium aromaticivorans DSM 12444, complete genomehypothetical protein4e-1891.7
NC_007298:2856104:285610428561042856970867Dechloromonas aromatica RCB, complete genomehypothetical protein2e-1789.7
NC_008782:1566172:158232415823241583199876Acidovorax sp. JS42, complete genomehypothetical protein9e-1787.4
NC_007722:2954876:298511729851172985932816Erythrobacter litoralis HTCC2594, complete genomehypothetical protein9e-1787.4
NC_011035:829945:871018871018871794777Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeprotein TraF1e-1686.7
NC_015422:3493396:349621034962103497085876Alicycliphilus denitrificans K601 chromosome, complete genomeTraF-like protein2e-1685.9
NC_015580:1584078:160400916040091604845837Novosphingobium sp. PP1Y, complete genomeconjugal transfer pilus assembly protein TraF1e-1583.2
NC_010554:2646806:266078226607822661726945Proteus mirabilis HI4320, complete genomepilus assembly3e-1272.4
NC_007490:76838:793397933980172834Rhodobacter sphaeroides 2.4.1 plasmid D, complete sequenceTraF2e-1169.3