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Query: NC_009378:62215:83962 Yersinia pestis Pestoides F plasmid MT, complete sequence

Start: 83962, End: 86781, Length: 2820

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009787:17344:85838583114652883Escherichia coli E24377A plasmid pETEC_35, complete sequenceprotein TraG2e-170600
NC_009998:62000:57357333862814Shewanella baltica OS195 plasmid pS19501, complete sequenceTraG domain protein5e-62240
NC_007722:2954876:2980976298097629836782703Erythrobacter litoralis HTCC2594, complete genomeTraG5e-40167
NC_015580:1584078:1599841159984116025432703Novosphingobium sp. PP1Y, complete genomeconjugal transfer mating pair stabilization protein TraG1e-36155
NC_007794:2304768:2307355230735523100572703Novosphingobium aromaticivorans DSM 12444, complete genomeTraG-like1e-34149
NC_007490:76838:8183781837852473411Rhodobacter sphaeroides 2.4.1 plasmid D, complete sequenceTraG8e-28126
NC_015422:3493396:3498565349856535013362772Alicycliphilus denitrificans K601 chromosome, complete genomeTraG domain-containing protein4e-25117
NC_007298:2856104:2858449285844928612232775Dechloromonas aromatica RCB, complete genomehypothetical protein8e-25116
NC_008782:1566172:1578073157807315808442772Acidovorax sp. JS42, complete genomeTraG domain protein1e-24115
NC_010793:1811401:1859697185969718623242628Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraG1e-23112
NC_011035:829945:8663268663268693283003Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeprotein TraG4e-1894.4
NC_010793:1508974:1516419151641915187702352Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraG1e-1482.8
NC_010793:1158279:1172045117204511743962352Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraG1e-1482.8
NC_010793:416849:4237504237504260772328Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraG1e-1482.4
NC_007575:827222:8358458358458391263282Sulfurimonas denitrificans DSM 1251, complete genomehypothetical protein5e-1480.5
NC_010554:2646806:2655818265581826593873570Proteus mirabilis HI4320, complete genomepilus assembly protein2e-0758.9