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Query: NC_009378:62215:81877 Yersinia pestis Pestoides F plasmid MT, complete sequence

Start: 81877, End: 82599, Length: 723

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008118:56777:783997839979121723Yersinia pestis Nepal516 plasmid pMT, complete sequencehypothetical protein1e-130465
NC_005815:61148:105060105060105782723Yersinia pestis biovar Microtus str. 91001 plasmid pMT1, complete1e-130465
NC_008313:959638:978531978531979193663Ralstonia eutropha H16 chromosome 1, complete sequencehypothetical protein2e-24112
NC_007404:974461:983107983107983757651Thiobacillus denitrificans ATCC 25259, complete genomehypothetical protein1e-1067
NC_011146:482440:491894491894492571678Geobacter bemidjiensis Bem, complete genomehypothetical protein1e-1067
NC_005773:5636606:564525256452525645896645Pseudomonas syringae pv. phaseolicola 1448A, complete genomehypothetical protein6e-0857.8