Pre_GI: BLASTP Hits

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Query: NC_009142:2565561:2583740 Saccharopolyspora erythraea NRRL 2338, complete genome

Start: 2583740, End: 2585053, Length: 1314

Host Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015589:3053504:3051538305153830535321995Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeATP-binding region ATPase domain-containing protein2e-24114
NC_004369:2968251:2968251296825129695401290Corynebacterium efficiens YS-314, complete genomeputative two-component sensory kinase9e-1788.6
NC_014209:1487699:1504499150449915056651167Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,DegS sensor signal transduction histidine kinase3e-1686.7
NC_008148:1567703:1570582157058215718051224Rubrobacter xylanophilus DSM 9941, complete genomeperiplasmic sensor signal transduction histidine kinase4e-1583.2
NC_019771:1356000:1365602136560213715925991Anabaena cylindrica PCC 7122, complete genomemulti-sensor signal transduction multi-kinase6e-1582.4
NC_019897:4014485:4039610403961040407611152Thermobacillus composti KWC4 chromosome, complete genomehistidine kinase1e-1378.6
NC_010571:2041277:2067947206794720691041158Opitutus terrae PB90-1, complete genomeintegral membrane sensor signal transduction histidine kinase1e-1378.2
NC_009767:5464796:5465677546567754677252049Roseiflexus castenholzii DSM 13941, complete genomeintegral membrane sensor signal transduction histidine kinase2e-1377.8
NC_017955:2494640:2513712251371225148511140Modestobacter marinus, complete genometwo component integral membrane sensor signal transduction histidine kinase1e-1377.8
NC_008699:1067855:1070611107061110717891179Nocardioides sp. JS614, complete genomehistidine kinase, dimerisation and phosphoacceptor region2e-1377.4
NC_016935:75186:9457094570957241155Paenibacillus mucilaginosus 3016 chromosome, complete genomehistidine kinase2e-1377.4
NC_015690:75223:9453394533956871155Paenibacillus mucilaginosus KNP414 chromosome, complete genomehistidine kinase2e-1377.4
NC_003272:2560329:2564524256452425673582835Nostoc sp. PCC 7120, complete genometwo-component sensor histidine kinase4e-1376.3
NC_020995:2255521:2256907225690722579741068Enterococcus casseliflavus EC20, complete genometwo-component system sensor histidine kinase1e-1275.1
NC_006177:520055:5342435342435361441902Symbiobacterium thermophilum IAM 14863, complete genometwo-component sensor histidine kinase1e-1274.7
NC_013947:656140:6795396795396806811143Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehistidine kinase1e-1274.7
NC_014829:3877701:3893197389319738943301134Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeDegS sensor signal transduction histidine kinase1e-1274.7
NC_014008:1246642:1263286126328612654422157Coraliomargarita akajimensis DSM 45221 chromosome, complete genomehistidine kinase1e-1274.7
NC_009328:448224:4936944936944947191026Geobacillus thermodenitrificans NG80-2 chromosome, complete genometwo-component sensor histidine kinase1e-1274.7
NC_011146:2200142:2217672221767222191411470Geobacter bemidjiensis Bem, complete genomemulti-sensor signal transduction histidine kinase3e-1273.2
NC_009659:1024201:1030147103014710320271881Janthinobacterium sp. Marseille chromosome, complete genomesensory box histidine kinase4e-1272.8
NC_015690:3883243:3890848389084838926351788Paenibacillus mucilaginosus KNP414 chromosome, complete genomeTwo-component protein Kinase5e-1272.8
NC_007795:1922000:1973581197358119746241044Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehistidine kinase, putative6e-1272.4
NC_003888:4031299:4032042403204240333671326Streptomyces coelicolor A3(2), complete genometwo-component system sensor kinase6e-1272.4
NC_015683:2469481:2471806247180624730021197Corynebacterium ulcerans BR-AD22 chromosome, complete genometwo-component system sensor kinase protein6e-1272.4
NC_010718:2460893:2471212247121224724021191Natranaerobius thermophilus JW/NM-WN-LF, complete genomehistidine kinase6e-1272.4
NC_016935:1306472:1315873131587313176601788Paenibacillus mucilaginosus 3016 chromosome, complete genomeTwo-component protein Kinase5e-1272.4
NC_007650:1192310:1195310119531011967011392Burkholderia thailandensis E264 chromosome II, complete sequencesensory box histidine kinase/response regulator1e-1171.6
NC_014960:1910202:1925461192546119270711611Anaerolinea thermophila UNI-1, complete genomeABC transporter ATP-binding protein3e-1170.5
NC_014829:3305762:3306396330639633074361041Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeintegral membrane sensor signal transduction histidine kinase3e-1170.1
NC_007907:5185510:5245286524528652476072322Desulfitobacterium hafniense Y51, complete genomehypothetical protein4e-1169.7
NC_007907:4692336:4711510471151047129581449Desulfitobacterium hafniense Y51, complete genomehypothetical protein5e-1169.3
NC_015589:3241364:325278932527893253496708Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeATP-binding region ATPase domain-containing protein6e-1169.3
NC_008752:4665699:4686650468665046880861437Acidovorax avenae subsp. citrulli AAC00-1, complete genomeintegral membrane sensor signal transduction histidine kinase9e-1168.6
NC_016114:3275004:3281501328150132829281428Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeintegral membrane sensor signal transduction histidine kinase9e-1168.6
NC_014210:2372813:2386026238602623873601335Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,integral membrane sensor signal transduction histidine kinase9e-1168.6
NC_011830:1288984:1300049130004913023882340Desulfitobacterium hafniense DCB-2, complete genomemulti-sensor signal transduction histidine kinase1e-1068.2
NC_012914:6583000:6613525661352566146851161Paenibacillus sp. JDR-2, complete genomeHistidine kinase1e-1068.2
NC_014391:3445672:3461080346108034622341155Micromonospora aurantiaca ATCC 27029 chromosome, complete genomehistidine kinase dimerization and phosphoacceptor region2e-1067.8
NC_016641:945284:9630959630959642551161Paenibacillus terrae HPL-003 chromosome, complete genomesensor protein degS2e-1067.8
NC_016113:11500:3003030030312051176Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencesensor kinase2e-1067.4
NC_016935:7426389:7434146743414674359631818Paenibacillus mucilaginosus 3016 chromosome, complete genomeLuxR family two component transcriptional regulator3e-1067
NC_013131:8029621:8051812805181280530111200Catenulispora acidiphila DSM 44928, complete genomehistidine kinase3e-1067
NC_015065:18189:3935139351424523102Acidobacterium sp. MP5ACTX9 plasmid pACIX902, complete sequenceintegral membrane sensor signal transduction histidine kinase3e-1067
UCMB5137:174593:1989711989712007611791Bacillus atrophaeus UCMB-5137two-component hybrid sensor and regulator4e-1066.6
NC_015376:1752883:1753907175390717561322226Burkholderia gladioli BSR3 chromosome chromosome 2, completeMulti-sensor signal transduction histidine kinase3e-1066.6
NC_013406:6568273:6594794659479465959481155Paenibacillus sp. Y412MC10 chromosome, complete genomeHistidine kinase5e-1066.2
NC_002570:832480:8489688489688501491182Bacillus halodurans C-125, complete genometwo-component sensor histidine kinase6e-1065.9
NC_010572:188500:2099672099672111511185Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative two-component system sensor kinase7e-1065.9
NC_009483:1779601:1796437179643717976781242Geobacter uraniireducens Rf4 chromosome, complete genomeputative signal transduction histidine kinase7e-1065.5
NC_016887:3255500:3263650326365032653681719Nocardia cyriacigeorgica GUH-2, complete genometwo-component system sensor kinase, putative GAF domains, dosS gene1e-0965.1
NC_014318:1320170:1337067133706713382001134Amycolatopsis mediterranei U32 chromosome, complete genometwo-component system histidine kinase2e-0964.3
NC_017186:1320186:1337083133708313382161134Amycolatopsis mediterranei S699 chromosome, complete genometwo-component system histidine kinase2e-0964.3
NC_013929:1584906:1603147160314716041541008Streptomyces scabiei 87.22 chromosome, complete genometwo component sensor kinase2e-0964.3
NC_018720:993869:1020155102015510215371383Bifidobacterium asteroides PRL2011 chromosome, complete genometwo-component system sensor kinase1e-0964.3
NC_008009:4421992:4421992442199244250483057Acidobacteria bacterium Ellin345, complete genomeputative signal transduction histidine kinase3e-0963.5
NC_018750:1591895:1609088160908816102331146Streptomyces venezuelae ATCC 10712, complete genomeputative two-component system sensor kinase3e-0963.5
NC_015703:3325780:333229833322983333104807Runella slithyformis DSM 19594 chromosome, complete genomeputative signal transduction histidine kinase4e-0962.8
NC_008148:2498000:2526117252611725280391923Rubrobacter xylanophilus DSM 9941, complete genomemulti-sensor signal transduction histidine kinase7e-0962.4
NC_020054:6111419:6148038614803861499691932Fibrella aestuarina BUZ 2 drat genometwo-component system, NarL family, sensor kinase7e-0962.4
NC_014960:1697818:1729807172980717309401134Anaerolinea thermophila UNI-1, complete genometwo-component sensor histidine kinase6e-0962.4
NC_020054:2147857:2153110215311021546181509Fibrella aestuarina BUZ 2 drat genomehistidine kinase9e-0962
NC_014622:4517709:4538343453834345401331791Paenibacillus polymyxa SC2 chromosome, complete genomeLuxR family transcriptional regulator9e-0962
NC_007204:696972:7178647178647199872124Psychrobacter arcticus 273-4, complete genomesignal transduction histidine kinase sensor8e-0962
NC_010086:20876:4489744897462761380Burkholderia multivorans ATCC 17616 chromosome 2, completeintegral membrane sensor signal transduction histidine kinase8e-0962
NC_008025:1799106:1813191181319118148851695Deinococcus geothermalis DSM 11300, complete genomeperiplasmic sensor signal transduction histidine kinase1e-0861.6
NC_013739:717352:7210357210357221741140Conexibacter woesei DSM 14684, complete genomeintegral membrane sensor signal transduction histidine kinase1e-0861.6
NC_009901:2787978:2787978278797827912593282Shewanella pealeana ATCC 700345, complete genomehistidine kinase1e-0861.6
NC_002944:1881405:1903102190310219046401539Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein2e-0860.8
NC_010627:532407:5309505309505324101461Burkholderia phymatum STM815 plasmid pBPHY02, complete sequenceintegral membrane sensor signal transduction histidine kinase2e-0860.5
NC_010627:463646:4645854645854662101626Burkholderia phymatum STM815 plasmid pBPHY02, complete sequencemulti-sensor signal transduction histidine kinase3e-0860.1
NC_015856:4975815:4997349499734949987191371Collimonas fungivorans Ter331 chromosome, complete genomesensor histidine kinase3e-0860.1
NC_014314:238043:2589652589652603861422Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeputative PAS/PAC sensor protein4e-0859.7
NC_012483:1567253:1578154157815415813903237Acidobacterium capsulatum ATCC 51196, complete genometwo-component system sensor protein, putative4e-0859.7
NC_011662:535613:5367005367005380941395Thauera sp. MZ1T, complete genomemulti-sensor signal transduction histidine kinase6e-0859.3
NC_013929:6371019:6391491639149163927291239Streptomyces scabiei 87.22 chromosome, complete genometwo-component system sensor kinase6e-0859.3
NC_016047:3599095:3604688360468836058451158Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completesensor protein DegS5e-0859.3
NC_011830:1288984:1288984128898412904771494Desulfitobacterium hafniense DCB-2, complete genomehistidine kinase5e-0859.3
NC_014314:1485500:1504752150475215065751824Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completemulti-sensor signal transduction histidine kinase5e-0859.3
NC_011567:2556915:2574239257423925753841146Anoxybacillus flavithermus WK1, complete genomeSignal transduction histidine kinase8e-0858.9
NC_011886:1891077:1913122191312219147291608Arthrobacter chlorophenolicus A6, complete genomeGAF sensor signal transduction histidine kinase8e-0858.9
NC_019896:577594:5784635784635796201158Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeTwo component sensor kinase7e-0858.9
NC_017195:3426000:3444297344429734454541158Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completesensor protein DegS7e-0858.9
NC_013406:3672857:3691084369108436928891806Paenibacillus sp. Y412MC10 chromosome, complete genomeLuxR family two component transcriptional regulator7e-0858.9
NC_012660:3179980:3206798320679832079491152Pseudomonas fluorescens SBW25 chromosome, complete genomeputative two-component system sensor kinase7e-0858.9
NC_012491:1293086:1322463132246313242711809Brevibacillus brevis NBRC 100599, complete genometwo-component hybrid sensor and regulator1e-0758.2
NC_003295:199354:2122532122532136291377Ralstonia solanacearum GMI1000, complete genomePROBABLE TRANSMEMBRANE TWO COMPONENT SYSTEM SENSOR KINASE TRANSCRIPTION REGULATOR PROTEIN1e-0758.2
NC_016815:1085462:1101330110133011032371908Sinorhizobium fredii HH103 plasmid pSfHH103e complete sequenceputative sensor kinase protein1e-0758.2
NC_015690:7334786:7346928734692873483971470Paenibacillus mucilaginosus KNP414 chromosome, complete genomeresponse regulator2e-0757.8
NC_008741:15699:2588725887279712085Desulfovibrio vulgaris subsp. vulgaris DP4 plasmid pDVUL01,integral membrane sensor signal transduction histidine kinase2e-0757.8
NC_016935:7426389:7438666743866674404591794Paenibacillus mucilaginosus 3016 chromosome, complete genomeresponse regulator2e-0757.8
NC_018000:3371829:3373842337384233756021761Sinorhizobium fredii USDA 257 chromosome, complete genomesensor kinase protein2e-0757.8
NC_013552:1187299:1215292121529212163531062Dehalococcoides sp. VS, complete genomesensory box sensor histidine kinase2e-0757.4
NC_016584:5305417:5320330532033053214151086Desulfosporosinus orientis DSM 765 chromosome, complete genomehistidine kinase2e-0757.4
NC_016631:4423658:4435012443501244380293018Granulicella mallensis MP5ACTX8 chromosome, complete genomehistidine kinase2e-0757.4
NC_013595:3541012:3541674354167435427921119Streptosporangium roseum DSM 43021, complete genomeputative two-component system sensor kinase3e-0757
NC_015312:6717973:671860867186086719492885Pseudonocardia dioxanivorans CB1190 chromosome, complete genomehistidine kinase3e-0757
NC_013929:1119384:1127261112726111284631203Streptomyces scabiei 87.22 chromosome, complete genometwo-component system sensor kinase3e-0757
NC_009455:273519:304200304200304961762Dehalococcoides sp. BAV1 chromosome, complete genomehistidine kinase4e-0756.6
NC_018750:3741581:3758691375869137598181128Streptomyces venezuelae ATCC 10712, complete genomeputative two-component system sensor kinase4e-0756.6
NC_020410:198000:2198972198972210271131Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeSensory transduction protein kinase4e-0756.6
NC_015731:313676:3240973240973253891293Nitrosomonas sp. Is79A3 chromosome, complete genomeputative cache sensor protein3e-0756.6
NC_013207:19154:291672916729838672Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446histidine kinase3e-0756.6
NC_010609:1077453:1076405107640510774601056Lactobacillus reuteri JCM 1112, complete genometwo component sensor histidine kinase5e-0756.2
NC_015656:3200500:3220900322090032256934794Frankia symbiont of Datisca glomerata chromosome, complete genomeputative signal transduction histidine kinase5e-0756.2
NC_003888:7866148:7876048787604878772411194Streptomyces coelicolor A3(2), complete genomeprobable two-component system sensor kinase5e-0756.2
NC_013093:1036772:1053496105349610547461251Actinosynnema mirum DSM 43827, complete genomehistidine kinase5e-0756.2
NC_009973:77518:8527385273876812409Herpetosiphon aurantiacus ATCC 23779 plasmid pHAU01, completeputative signal transduction histidine kinase5e-0756.2
NC_014958:514225:5189025189025203411440Deinococcus maricopensis DSM 21211 chromosome, complete genomeintegral membrane sensor signal transduction histidine kinase4e-0756.2
NC_014147:765941:7705707705707725401971Moraxella catarrhalis RH4 chromosome, complete genometwo-component system nitrate/nitrite sensor histidine kinase NarX4e-0756.2
NC_009725:200071:2206612206612217911131Bacillus amyloliquefaciens FZB42, complete genomesensory transduction protein kinase6e-0755.8
NC_007356:1221500:1235417123541712365861170Dehalococcoides sp. CBDB1, complete genomesensor histidine kinase6e-0755.8
NC_014761:417377:4214104214104231041695Oceanithermus profundus DSM 14977 chromosome, complete genomeintegral membrane sensor signal transduction histidine kinase7e-0755.5
NC_013501:1140390:1152399115239911553022904Rhodothermus marinus DSM 4252, complete genomehistidine kinase7e-0755.5
NC_020272:3706722:3708448370844837095781131Bacillus amyloliquefaciens IT-45, complete genomesensor signal transduction histidine kinase1e-0655.1
NC_007644:3229:2327023270247331464Moorella thermoacetica ATCC 39073, complete genomeperiplasmic sensor signal transduction histidine kinase1e-0655.1
NC_009921:3854969:3885817388581738870341218Frankia sp. EAN1pec, complete genomeintegral membrane sensor signal transduction histidine kinase1e-0655.1
NC_013757:2630000:2644672264467226463841713Geodermatophilus obscurus DSM 43160, complete genomeputative signal transduction histidine kinase1e-0655.1
NC_013552:68003:8478484784858751092Dehalococcoides sp. VS, complete genomesensor histidine kinase1e-0655.1
NC_007168:665284:6812866812866823201035Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein1e-0654.7
NC_008322:2716676:2724047272404727258161770Shewanella sp. MR-7, complete genomesignal transduction histidine kinase, nitrate/nitrite-specific, NarQ1e-0654.7
NC_016582:6811273:6826277682627768277011425Streptomyces bingchenggensis BCW-1 chromosome, complete genomeputative two-component system sensor kinase1e-0654.7
NC_016599:3616204:3632671363267136345481878Owenweeksia hongkongensis DSM 17368 chromosome, complete genomesignal transduction histidine kinase1e-0654.7
NC_004547:2285092:2306203230620323080111809Erwinia carotovora subsp. atroseptica SCRI1043, complete genomenitrate/nitrite sensor kinase2e-0654.3
NC_008321:2649781:2656085265608526578541770Shewanella sp. MR-4, complete genomehistidine kinase, dimerisation and phosphoacceptor region2e-0654.3
NC_017218:1166844:1186511118651111889672457Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genomehistidine kinase2e-0654.3
NC_015381:2405446:2405446240544624075182073Burkholderia gladioli BSR3 chromosome 1, complete sequenceSensory box histidine kinase2e-0653.9
NC_017191:183500:2050982050982062281131Bacillus amyloliquefaciens XH7 chromosome, complete genomesensory transduction protein kinase2e-0653.9
NC_017188:177500:1991881991882003181131Bacillus amyloliquefaciens TA208 chromosome, complete genomeSensor histidine kinase2e-0653.9
NC_012483:1567253:1573082157308215760452964Acidobacterium capsulatum ATCC 51196, complete genometwo-component system sensor protein, putative3e-0653.5
NC_016631:4688000:4704749470474947078293081Granulicella mallensis MP5ACTX8 chromosome, complete genomehistidine kinase4e-0653.1
NC_016047:683368:7049477049477061101164Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completesensor histidine kinase YdfH4e-0653.1
NC_009921:4399000:4412349441234944136831335Frankia sp. EAN1pec, complete genomeintegral membrane sensor signal transduction histidine kinase4e-0653.1
NC_019673:1039258:1051355105135510526021248Saccharothrix espanaensis DSM 44229 complete genomeputative histidine kinase5e-0652.8
NC_014215:1929000:193729919372991938222924Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,Two-component system sensor kinase. Membrane protein6e-0652.4
NC_017353:646195:6603056603056613481044Staphylococcus lugdunensis N920143, complete genomeputative histidine kinase6e-0652.4
NC_019940:389979:4080324080324096451614Thioflavicoccus mobilis 8321 chromosome, complete genomePAS domain-containing protein7e-0652.4
NC_012796:3267569:3313025331302533149861962Desulfovibrio magneticus RS-1, complete genometwo-component sensor histidine kinase8e-0652
NC_014210:5752651:5758783575878357599311149Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,integral membrane sensor signal transduction histidine kinase9e-0652
NC_013959:1723037:1736003173600317372261224Sideroxydans lithotrophicus ES-1 chromosome, complete genomesignal transduction histidine kinase, nitrate/nitrite-specific, NarQ9e-0652
NC_015957:5310000:5318013531801353192151203Streptomyces violaceusniger Tu 4113 chromosome, complete genomeputative signal transduction histidine kinase9e-0652
NC_013729:4835452:4840812484081248419781167Kribbella flavida DSM 17836, complete genomehistidine kinase1e-0552