Pre_GI: BLASTP Hits

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Query: NC_008767:451983:476642 Neisseria meningitidis FAM18, complete genome

Start: 476642, End: 477025, Length: 384

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017515:1744500:176878617687861769169384Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein3e-68256
NC_017514:1721416:173181317318131732196384Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein3e-68256
NC_017513:449949:474829474829475212384Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein3e-68256
NC_017512:425085:444488444488444871384Neisseria meningitidis WUE 2594, complete genomehypothetical protein3e-68256
NC_017501:543000:553151553151553534384Neisseria meningitidis 8013, complete genomehypothetical protein3e-68256
NC_003116:658879:678935678935679318384Neisseria meningitidis Z2491, complete genomehypothetical protein3e-68256