Pre_GI: BLASTP Hits

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Query: NC_008767:451983:458437 Neisseria meningitidis FAM18, complete genome

Start: 458437, End: 458676, Length: 240

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003112:1824196:187227118722711872510240Neisseria meningitidis MC58, complete genomehypothetical protein3e-39160
NC_017512:425085:433479433479433706228Neisseria meningitidis WUE 2594, complete genomehypothetical protein9e-37152
NC_003116:658879:667552667552667779228Neisseria meningitidis Z2491, complete genomelipoprotein9e-37152
NC_013016:419604:425608425608425835228Neisseria meningitidis alpha14 chromosome, complete genomehypothetical protein2e-36150