Pre_GI: BLASTP Hits

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Query: NC_008767:2160000:2175625 Neisseria meningitidis FAM18, complete genome

Start: 2175625, End: 2176260, Length: 636

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017512:2209000:222152522215252222160636Neisseria meningitidis WUE 2594, complete genomeputative nicotinamidase (nicotine deamidase; NAMase)2e-119427
NC_017516:2220000:223503722350372235672636Neisseria meningitidis H44/76 chromosome, complete genomeisochorismatase family protein1e-118425
NC_002946:1902642:191054719105471911182636Neisseria gonorrhoeae FA 1090, complete genomePncA6e-116416
NC_011035:1908000:192142819214281922063636Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeprotein PncA2e-115414
NC_017511:1812000:182527118252711825906636Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeprotein PncA3e-115413
NC_019907:773944:788699788699789325627Liberibacter crescens BT-1 chromosome, complete genomenicotinamidase7e-1270.5
NC_016822:1431200:148600514860051486646642Shigella sonnei 53G, complete genomenicotinamidase/pyrazinamidase1e-1170.1
NC_017047:2260118:229055822905582291187630Rahnella aquatilis HX2 chromosome, complete genomenicotinamidase/pyrazinamidase6e-1167.8
NC_008390:2058500:207873620787362079368633Burkholderia cepacia AMMD chromosome 1, complete sequenceNicotinamidase2e-1066.2
NC_000961:888000:907656907656908198543Pyrococcus horikoshii OT3, complete genomepyrazinamidase/nicotinamidase9e-1063.5
NC_013501:931418:938168938168938800633Rhodothermus marinus DSM 4252, complete genomeNicotinamidase1e-0963.2
NC_010551:2007926:202804620280462028678633Burkholderia ambifaria MC40-6 chromosome 1, complete sequenceNicotinamidase1e-0963.2
NC_015966:2337833:234975223497522350384633Rhodothermus marinus SG0.5JP17-172 chromosome, complete genomeNicotinamidase1e-0963.2
NC_014121:2514544:251557025155702516211642Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completepyrazinamidase/nicotinamidase3e-0962
NC_004088:2366000:239016323901632390810648Yersinia pestis KIM, complete genomehypothetical protein7e-0960.5
NC_015680:369777:378690378690379235546Pyrococcus yayanosii CH1 chromosome, complete genomepyrazinamidase/nicotinamidase2e-0859.3
NC_013960:1587761:161487716148771615536660Nitrosococcus halophilus Nc4 chromosome, complete genomeNicotinamidase5e-0651.2
NC_014011:1264165:127181812718181272399582Aminobacterium colombiense DSM 12261 chromosome, complete genomeNicotinamidase8e-0650.4