Pre_GI: BLASTP Hits

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Query: NC_008767:2160000:2166442 Neisseria meningitidis FAM18, complete genome

Start: 2166442, End: 2166882, Length: 441

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017511:1812000:181811518181151818555441Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein2e-82303
NC_002946:1902642:191789619178961918318423Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein5e-79292
NC_017516:2220000:222640722264072226829423Neisseria meningitidis H44/76 chromosome, complete genomeputative lipoprotein1e-78290
NC_017512:2209000:221289522128952213317423Neisseria meningitidis WUE 2594, complete genomehypothetical protein3e-78290
NC_011035:1908000:191432919143291914712384Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeLipoprotein1e-70265