Pre_GI: BLASTP Hits

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Query: NC_008767:1739344:1748465 Neisseria meningitidis FAM18, complete genome

Start: 1748465, End: 1748749, Length: 285

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003112:1594000:160637016063701606654285Neisseria meningitidis MC58, complete genomehypothetical protein5e-45179
NC_017505:926801:938610938610938894285Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein7e-45178
NC_017514:761000:770549770549770833285Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein7e-45178
NC_017515:800000:808322808322808606285Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein1e-45181
NC_003112:1685330:169309216930921693376285Neisseria meningitidis MC58, complete genomehypothetical protein5e-45179
NC_003116:1734000:174241317424131742697285Neisseria meningitidis Z2491, complete genomeintegral membrane protein3e-45180
NC_008767:273759:285219285219285503285Neisseria meningitidis FAM18, complete genomeputative inner membrane protein2e-46184
NC_017505:1516348:152377215237721524056285Neisseria meningitidis alpha710 chromosome, complete genomeputative inner membrane protein7e-45178
NC_008767:1888950:189835318983531898637285Neisseria meningitidis FAM18, complete genomePutative integral membrane protein2e-46184
NC_010120:144000:152286152286152570285Neisseria meningitidis 053442, complete genomeputative integral membrane protein5e-45179