Pre_GI: BLASTP Hits

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Query: NC_008767:1739344:1745659 Neisseria meningitidis FAM18, complete genome

Start: 1745659, End: 1745889, Length: 231

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017505:926801:935812935812936042231Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein2e-27120
NC_008767:273759:282378282378282608231Neisseria meningitidis FAM18, complete genomeputative periplasmic protein2e-27120
NC_003112:1594000:160283316028331603117285Neisseria meningitidis MC58, complete genomehypothetical protein9e-27118
NC_003112:1685330:169612316961231696407285Neisseria meningitidis MC58, complete genomehypothetical protein9e-27118
NC_017515:800000:811183811183811413231Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein1e-26117
NC_008767:1888950:189553718955371895767231Neisseria meningitidis FAM18, complete genomehypothetical protein1e-25115
NC_010120:144000:155823155823156053231Neisseria meningitidis 053442, complete genomeconserved hypothetical protein1e-25115
NC_017505:1516348:152665015266501526880231Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein3e-25113
NC_017513:9081:199581995820188231Neisseria meningitidis G2136 chromosome, complete genomehypothetical protein3e-25113
NC_017514:761000:767725767725767955231Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein3e-25113
NC_017518:1558000:156727715672771567507231Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein3e-25113
NC_017518:1610803:161908716190871619317231Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein3e-25113
NC_017518:1701958:171447317144731714703231Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein3e-25113
NC_003116:1734000:173959917395991739829231Neisseria meningitidis Z2491, complete genomehypothetical protein3e-25113