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Query: NC_008710:703740:729894 Borrelia turicatae 91E135, complete genome

Start: 729894, End: 731168, Length: 1275

Host Lineage: Borrelia turicatae; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010673:703816:7324787324787337521275Borrelia hermsii DAH, complete genomehypothetical protein0773
NC_008095:6253610:6274722627472262760501329Myxococcus xanthus DK 1622, complete genomehydroxymethylglutaryl-CoA reductase4e-54212
NC_015978:352478:3775883775883788441257Lactobacillus sanfranciscensis TMW 1.1304 chromosome, complete3-hydroxy-3-methylglutaryl-coenzyme A reductase5e-51202
NC_015563:313283:3275653275653288541290Delftia sp. Cs1-4 chromosome, complete genomehydroxymethylglutaryl-CoA reductase, degradative7e-50198
NC_013446:3520500:3533461353346135347501290Comamonas testosteroni CNB-2, complete genomehydroxymethylglutaryl-CoA reductase1e-49197
NC_004193:241480:2454292454292467181290Oceanobacillus iheyensis HTE831, complete genomehydroxymethylglutaryl-CoA reductase1e-49197
NC_009464:2372607:2395089239508923963751287Uncultured methanogenic archaeon RC-I, complete genome3-hydroxy-3-methylglutaryl-coenzyme A reductase1e-47191
NC_016023:1143130:1155488115548811567771290Bacillus coagulans 36D1 chromosome, complete genomehydroxymethylglutaryl-CoA reductase, degradative1e-46187
NC_008543:323773:3436213436213449071287Burkholderia cenocepacia HI2424 chromosome 2, complete sequencehydroxymethylglutaryl-CoA reductase, degradative4e-46186
NC_014961:445717:4517744517744530541281Desulfurococcus mucosus DSM 2162 chromosome, complete genomehydroxymethylglutaryl-CoA reductase, degradative7e-42171
NC_014820:1989500:1990738199073819919851248Cenarchaeum symbiosum A, complete genomehydroxymethylglutaryl-CoA reductase4e-39162
NC_015144:802288:8181518181518195061356Weeksella virosa DSM 16922 chromosome, complete genomehydroxymethylglutaryl-CoA reductase, degradative6e-37155