Pre_GI: BLASTP Hits

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Query: NC_008600:4626464:4633952 Bacillus thuringiensis str. Al Hakam, complete genome

Start: 4633952, End: 4635052, Length: 1101

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:4588000:4591618459161845927181101Bacillus cereus F837/76 chromosome, complete genomeMetallo-dependent hydrolase, subgroup B0746
NC_012472:4630485:4637970463797046390701101Bacillus cereus 03BB102, complete genomehypothetical protein0746
NC_014335:4566692:4569540456954045706401101Bacillus cereus biovar anthracis str. CI chromosome, completeamidohydrolase family protein0736
NC_017200:4632000:4642249464224946433491101Bacillus thuringiensis serovar finitimus YBT-020 chromosome,dihydroorotase0732
NC_014171:4681822:4684669468466946857691101Bacillus thuringiensis BMB171 chromosome, complete genomedihydroorotase0731
NC_003909:4614789:4614789461478946158891101Bacillus cereus ATCC 10987, complete genomedihydroorotase0731
NC_004722:4767294:4769132476913247702321101Bacillus cereus ATCC 14579, complete genomedihydroorotase0730
NC_011725:4799905:4800986480098648020861101Bacillus cereus B4264 chromosome, complete genomedihydroorotase0729
NC_011658:4616933:4618014461801446191141101Bacillus cereus AH187 chromosome, complete genomedihydroorotase0728
NC_016771:4569941:4571779457177945728791101Bacillus cereus NC7401, complete genomehypothetical protein0728
NC_011969:4556296:4559868455986845609681101Bacillus cereus Q1 chromosome, complete genomedihydroorotase0726
NC_011772:4763542:4771688477168847727881101Bacillus cereus G9842, complete genomehypothetical protein0725
NC_004193:3325612:3335354333535433364631110Oceanobacillus iheyensis HTE831, complete genomedihydroorotase6e-102370
NC_014829:3964616:3983130398313039842181089Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeamidohydrolase2e-98359
NC_014831:1843835:1872965187296518741071143Thermaerobacter marianensis DSM 12885 chromosome, complete genomeamidohydrolase1e-54213
NC_015873:790961:7990177990178001651149Megasphaera elsdenii DSM 20460, complete genomehypothetical protein4e-33142
NC_009921:3666898:3688413368841336896121200Frankia sp. EAN1pec, complete genomeamidohydrolase2e-31136
NC_015065:18189:2943529435307511317Acidobacterium sp. MP5ACTX9 plasmid pACIX902, complete sequenceamidohydrolase2e-26120