Pre_GI: BLASTP Hits

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Query: NC_008600:4509793:4522389 Bacillus thuringiensis str. Al Hakam, complete genome

Start: 4522389, End: 4522718, Length: 330

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012581:4509491:452177445217744522103330Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein3e-47186
NC_012472:4515909:452857845285784528907330Bacillus cereus 03BB102, complete genomehypothetical protein3e-47186
NC_005945:4508304:452055145205514520874324Bacillus anthracis str. Sterne, complete genomehypothetical protein3e-46183
NC_003997:4507939:451934045193404519663324Bacillus anthracis str. Ames, complete genomehypothetical protein3e-46183
NC_014335:4442500:445589544558954456218324Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein3e-46183
NC_007530:4507742:451946745194674519790324Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein3e-46183
NC_006274:4563455:457592745759274576250324Bacillus cereus E33L, complete genomegroup-specific protein1e-45181
NC_017208:4692478:470517247051724705495324Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein3e-45180
NC_004722:4645678:466140246614024661725324Bacillus cereus ATCC 14579, complete genomehypothetical protein4e-45179
NC_011969:4432454:444625944462594446582324Bacillus cereus Q1 chromosome, complete genomehypothetical protein1e-44178
NC_016771:4445815:445963044596304459953324Bacillus cereus NC7401, complete genomehypothetical protein1e-44178
NC_005957:4502733:451624845162484516571324Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein1e-44178
NC_011725:4671432:468565146856514685974324Bacillus cereus B4264 chromosome, complete genomehypothetical protein9e-45178
NC_003909:4484278:449997344999734500296324Bacillus cereus ATCC 10987, complete genomehypothetical protein7e-45178
NC_017200:4520482:453180745318074532130324Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein7e-45178
NC_010184:4532262:454541945454194545742324Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein2e-43173
NC_011772:4638000:465035746503574650614258Bacillus cereus G9842, complete genomehypothetical protein1e-31135
NC_014171:4560061:457578045757804575992213Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein3e-23107
NC_016779:4475425:448809444880944488231138Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-0962
NC_012659:4507966:451936745193674519504138Bacillus anthracis str. A0248, complete genomehypothetical protein1e-0962
NC_011773:4569600:458505945850594585196138Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-0962
NC_011658:4492356:450584745058474505984138Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-0858.5