Pre_GI: BLASTN Hits

Some Help

Query: NC_008593:1631438 Clostridium novyi NT, complete genome

Start: 1631438, End: 1650596, Length: 19159

Host Lineage: Clostridium novyi; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain (NT) was created so that it lacks the lethal toxin. Injection of spores of this organism into mice harboring tumors resulted in an increased immune response and destruction of the tumor tissue in a method known as COBALT (combination bacteriolytic therapy) when the spores along with chemotherapeutic agents or radiation are co-administered. The anaerobic bacteria preferentially target hypoxic cancer tissue and stimulate immune responses to that tissue. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. Clostridium novyi is an anaerobic bacterium found in soil, aquatic sediments, and intestinal tract of both animals and humans. Some types produce lethal toxins.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014328:93839393839395781019418Clostridium ljungdahlii ATCC 49587 chromosome, complete genome8e-68266BLASTN svgBLASTP svg
NC_012563:32881243288124330917721054Clostridium botulinum A2 str. Kyoto, complete genome1e-57232BLASTN svgBLASTP svg
NC_010674:11244311124431114553121101Clostridium botulinum B str. Eklund 17B, complete genome1e-57232BLASTN svgBLASTP svg
NC_003030:15100001510000154543435435Clostridium acetobutylicum ATCC 824, complete genome1e-54222BLASTN svgBLASTP svg
NC_010723:10840001084000110630222303Clostridium botulinum E3 str. Alaska E43, complete genome4e-51210BLASTN svgBLASTP svg
NC_021182:2059143*2059143208239023248Clostridium pasteurianum BC1, complete genome6e-50206BLASTN svgBLASTP svg
NC_010520:31205003120500313949618997Clostridium botulinum A3 str. Loch Maree, complete genome2e-49204BLASTN svgBLASTP svg
NC_004557:2078000*2078000210049622497Clostridium tetani E88, complete genome2e-43184BLASTN svgBLASTP svg
NC_020291:12668851266885130737240488Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome9e-40172BLASTN svgBLASTP svg
NC_008262:784878*78487882991045033Clostridium perfringens SM101, complete genome8e-37163BLASTN svgBLASTP svg
NC_003366:84200084200086047418475Clostridium perfringens str. 13, complete genome5e-32147BLASTN svgBLASTP svg
NC_010674:14965001496500152566029161Clostridium botulinum B str. Eklund 17B, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_012225:1657248*1657248168304825801Brachyspira hyodysenteriae WA1, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_015638:2045500*2045500206559920100Lacinutrix sp. 5H-3-7-4 chromosome, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_014614:35674635674640601049265Clostridium sticklandii, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014328:26435882643588266721023623Clostridium ljungdahlii ATCC 49587 chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_010723:14650971465097149459929503Clostridium botulinum E3 str. Alaska E43, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_010718:46440546440548434419940Natranaerobius thermophilus JW/NM-WN-LF, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014150:3085013*3085013310947924467Brachyspira murdochii DSM 12563 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010380:12465512465515098226328Streptococcus pneumoniae Hungary19A-6, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_018607:135612*13561217740241791Brachyspira pilosicoli B2904 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_008023:35663356635809922437Streptococcus pyogenes MGAS2096, complete genome9e-0660BLASTN svgBLASTP svg
NC_008021:35661356615809922439Streptococcus pyogenes MGAS9429, complete genome9e-0660BLASTN svgBLASTP svg
NC_007296:35661356616061124951Streptococcus pyogenes MGAS6180, complete genome9e-0660BLASTN svgBLASTP svg
NC_003485:35971359715826622296Streptococcus pyogenes MGAS8232, complete genome9e-0660BLASTN svgBLASTP svg