Pre_GI: BLASTN Hits

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Query: NC_008262:2025699 Clostridium perfringens SM101, complete genome

Start: 2025699, End: 2044081, Length: 18383

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007530:5197854*5197854521982221969Bacillus anthracis str. 'Ames Ancestor', complete genome1e-1075.8BLASTN svgBLASTP svg
NC_003997:5200805*5200805522349422690Bacillus anthracis str. Ames, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_005945:5202176*5202176522486522690Bacillus anthracis str. Sterne, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_012472:5239944*5239944525821718274Bacillus cereus 03BB102, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_004722:5381208*5381208540929928092Bacillus cereus ATCC 14579, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_014335:5165211*5165211518430019090Bacillus cereus biovar anthracis str. CI chromosome, complete1e-1075.8BLASTN svgBLASTP svg
NC_006274:5267585*5267585529331825734Bacillus cereus E33L, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_016012:879972*87997290262722656Candidatus Arthromitus sp. SFB-rat-Yit, complete genome8e-34153BLASTN svgBLASTP svg
NC_012563:17043451704345173190427560Clostridium botulinum A2 str. Kyoto, complete genome9e-86325BLASTN svgBLASTP svg
NC_012563:3556763*3556763357533918577Clostridium botulinum A2 str. Kyoto, complete genome3e-42180BLASTN svgBLASTP svg
NC_010516:3903867*3903867395059846732Clostridium botulinum B1 str. Okra, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010516:3368951*3368951339250323553Clostridium botulinum B1 str. Okra, complete genome3e-42180BLASTN svgBLASTP svg
NC_013316:29680002968000299190223903Clostridium difficile R20291, complete genome9e-49202BLASTN svgBLASTP svg
NC_014328:3747973*3747973377009922127Clostridium ljungdahlii ATCC 49587 chromosome, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_008593:980731980731100500724277Clostridium novyi NT, complete genome4e-20107BLASTN svgBLASTP svg
NC_008261:12495951249595127220022606Clostridium perfringens ATCC 13124, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008261:576923*57692359692520003Clostridium perfringens ATCC 13124, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_008261:21172072117207214023523029Clostridium perfringens ATCC 13124, complete genome9e-0660BLASTN svgBLASTP svg
NC_008262:24980002498000252144223443Clostridium perfringens SM101, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_008262:784878*78487882991045033Clostridium perfringens SM101, complete genome4e-60240BLASTN svgBLASTP svg
NC_008262:17959141795914181428418371Clostridium perfringens SM101, complete genome9e-0660BLASTN svgBLASTP svg
NC_008262:17214961721496174021318718Clostridium perfringens SM101, complete genome1e-57232BLASTN svgBLASTP svg
NC_008262:90400090400092609922100Clostridium perfringens SM101, complete genome6e-56226BLASTN svgBLASTP svg
NC_003366:21431732143173216513121959Clostridium perfringens str. 13, complete genome04113BLASTN svgBLASTP svg
NC_020291:11498871149887117209922213Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome1e-20109BLASTN svgBLASTP svg
NC_003454:63500*6350010726843769Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete5e-0763.9BLASTN svgBLASTP svg