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Query: NC_008262:1835613 Clostridium perfringens SM101, complete genome

Start: 1835613, End: 1855043, Length: 19431

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008261:2157713*2157713217590318191Clostridium perfringens ATCC 13124, complete genome011470BLASTN svgBLASTP svg
NC_012563:2680246*2680246272077540530Clostridium botulinum A2 str. Kyoto, complete genome1e-134488BLASTN svgBLASTP svg
NC_010520:2585014*2585014262041935406Clostridium botulinum A3 str. Loch Maree, complete genome3e-132480BLASTN svgBLASTP svg
NC_010516:2511035*2511035254588934855Clostridium botulinum B1 str. Okra, complete genome3e-132480BLASTN svgBLASTP svg
NC_020291:1464500*1464500148221117712Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-114420BLASTN svgBLASTP svg
NC_012563:2721658*2721658274175820101Clostridium botulinum A2 str. Kyoto, complete genome6e-87329BLASTN svgBLASTP svg
NC_014328:1405484*1405484142841522932Clostridium ljungdahlii ATCC 49587 chromosome, complete genome7e-56226BLASTN svgBLASTP svg
NC_011296:1299388*1299388132999530608Thermodesulfovibrio yellowstonii DSM 11347, complete genome1e-20109BLASTN svgBLASTP svg
NC_019970:1343670*1343670136621022541Thermoanaerobacterium thermosaccharolyticum M0795, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_018604:2303239*2303239232188618648Brachyspira pilosicoli WesB complete genome1e-1179.8BLASTN svgBLASTP svg
NC_018607:2184832*2184832220348618655Brachyspira pilosicoli B2904 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014330:841841*84184186434222502Brachyspira pilosicoli 95/1000 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_015696:105748*10574812926823521Francisella sp. TX077308 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014721:1028841*1028841104757818738Caldicellulosiruptor kristjanssonii 177R1B chromosome, complete2e-1075.8BLASTN svgBLASTP svg
NC_011653:1463743*1463743148807524333Thermosipho africanus TCF52B, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014657:944000*94400096534721348Caldicellulosiruptor owensensis OL chromosome, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_007799:55590055590058009124192Ehrlichia chaffeensis str. Arkansas, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_012225:1657248*1657248168304825801Brachyspira hyodysenteriae WA1, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_015978:11365611365613662622971Lactobacillus sanfranciscensis TMW 1.1304 chromosome, complete2e-0971.9BLASTN svgBLASTP svg
NC_014652:1758787*1758787178282424038Caldicellulosiruptor hydrothermalis 108 chromosome, complete9e-0969.9BLASTN svgBLASTP svg
NC_006449:58436*584367815519720Streptococcus thermophilus CNRZ1066, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_006448:59654*596548486525212Streptococcus thermophilus LMG 18311, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_011772:3787500*3787500381637528876Bacillus cereus G9842, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_011898:513835*51383553654722713Clostridium cellulolyticum H10, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_013771:80304280304282533222291Cyanobacterium UCYN-A, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014166:455378*45537847468719310Arcobacter nitrofigilis DSM 7299 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_020125:288706*28870631234423639Riemerella anatipestifer RA-CH-2, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_007335:944175*94417597349129317Prochlorococcus marinus str. NATL2A, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_006832:77628677628679962623341Ehrlichia ruminantium str. Welgevonden, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_006831:77273777273779560022864Ehrlichia ruminantium str. Gardel, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_005957:3638750*3638750365855919810Bacillus thuringiensis serovar konkukian str. 97-27, complete6e-0763.9BLASTN svgBLASTP svg
NC_005945:3615623*3615623363438618764Bacillus anthracis str. Sterne, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_005042:1480761*1480761151006629306Prochlorococcus marinus subsp. marinus str. CCMP1375, complete6e-0763.9BLASTN svgBLASTP svg
NC_003997:3617000*3617000367460757608Bacillus anthracis str. Ames, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_002952:1291444*1291444131490923466Staphylococcus aureus subsp. aureus MRSA252, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_007530:3616828*3616828367637859551Bacillus anthracis str. 'Ames Ancestor', complete genome6e-0763.9BLASTN svgBLASTP svg
NC_008600:3643905*3643905366318919285Bacillus thuringiensis str. Al Hakam, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_005295:79643779643781969823262Ehrlichia ruminantium str. Welgevonden, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014932:985882*985882103391148030Bartonella clarridgeiae 73, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014758:1349494*1349494137004820555Calditerrivibrio nitroreducens DSM 19672 chromosome, complete6e-0763.9BLASTN svgBLASTP svg
NC_014335:3567931*3567931358636818438Bacillus cereus biovar anthracis str. CI chromosome, complete6e-0763.9BLASTN svgBLASTP svg
NC_014166:29596882959688298355023863Arcobacter nitrofigilis DSM 7299 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_012472:3661912*3661912368119019279Bacillus cereus 03BB102, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_010546:47860004786000480938923390Cyanothece sp. ATCC 51142 chromosome circular, complete sequence6e-0763.9BLASTN svgBLASTP svg
NC_009782:1327340*1327340135080023461Staphylococcus aureus subsp. aureus Mu3, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_006142:683000*68300070514022141Rickettsia typhi str. Wilmington, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015391:695350*69535071865123302Carnobacterium sp. 17-4 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015760:61345*613458629324949Streptococcus salivarius CCHSS3, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_012121:897866*89786692042622561Staphylococcus carnosus subsp. carnosus TM300, complete genome9e-0660BLASTN svgBLASTP svg
NC_010336:733751*73375175293719187Francisella philomiragia subsp. philomiragia ATCC 25017, complete9e-0660BLASTN svgBLASTP svg
NC_009004:1770497*1770497179533924843Lactococcus lactis subsp. cremoris MG1363, complete genome9e-0660BLASTN svgBLASTP svg
NC_008817:1443983*1443983147127227290Prochlorococcus marinus str. MIT 9515, complete genome9e-0660BLASTN svgBLASTP svg
NC_008527:740060*74006076330623247Lactococcus lactis subsp. cremoris SK11, complete genome9e-0660BLASTN svgBLASTP svg
NC_006274:3697255*3697255372593028676Bacillus cereus E33L, complete genome9e-0660BLASTN svgBLASTP svg
NC_005072:1405884*1405884143384727964Prochlorococcus marinus subsp. pastoris str. CCMP1986, complete9e-0660BLASTN svgBLASTP svg