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Query: NC_008262:1795914 Clostridium perfringens SM101, complete genome

Start: 1795914, End: 1814284, Length: 18371

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008261:21172072117207214023523029Clostridium perfringens ATCC 13124, complete genome010950BLASTN svgBLASTP svg
NC_003366:19018981901898192440722510Clostridium perfringens str. 13, complete genome010900BLASTN svgBLASTP svg
NC_010674:29302592930259294957619318Clostridium botulinum B str. Eklund 17B, complete genome01203BLASTN svgBLASTP svg
NC_010723:27351962735196275388618691Clostridium botulinum E3 str. Alaska E43, complete genome01164BLASTN svgBLASTP svg
NC_012563:29791472979147300249023344Clostridium botulinum A2 str. Kyoto, complete genome2e-170607BLASTN svgBLASTP svg
NC_008593:84129184129186462123331Clostridium novyi NT, complete genome7e-142511BLASTN svgBLASTP svg
NC_013192:81585481585483809922246Leptotrichia buccalis DSM 1135, complete genome4e-63250BLASTN svgBLASTP svg
NC_015562:62700062700064529218293Methanotorris igneus Kol 5 chromosome, complete genome5e-35157BLASTN svgBLASTP svg
NC_000909:201000*20100022113320134Methanocaldococcus jannaschii DSM 2661, complete genome5e-35157BLASTN svgBLASTP svg
NC_013156:431795*43179546884337049Methanocaldococcus fervens AG86, complete genome7e-31143BLASTN svgBLASTP svg
NC_014222:18687618687620859921724Methanococcus voltae A3 chromosome, complete genome2e-28135BLASTN svgBLASTP svg
NC_010520:28074292807429283431926891Clostridium botulinum A3 str. Loch Maree, complete genome7e-28133BLASTN svgBLASTP svg
NC_015636:1477221*1477221150259925379Methanothermococcus okinawensis IH1 chromosome, complete genome2e-25125BLASTN svgBLASTP svg
NC_013407:1610221*1610221163174921529Methanocaldococcus vulcanius M7, complete genome2e-19105BLASTN svgBLASTP svg
NC_007681:1300068*1300068132484524778Methanosphaera stadtmanae DSM 3091, complete genome6e-19103BLASTN svgBLASTP svg
NC_014122:39385639385641638122526Methanocaldococcus infernus ME chromosome, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_015574:2057602*2057602208210924508Methanobacterium sp. SWAN-1 chromosome, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_013926:1205443*1205443122506719625Aciduliprofundum boonei T469 chromosome, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_003413:181525*18152520476123237Pyrococcus furiosus DSM 3638, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_008261:12495951249595127220022606Clostridium perfringens ATCC 13124, complete genome1e-1385.7BLASTN svgBLASTP svg
NC_008261:81729581729584209724803Clostridium perfringens ATCC 13124, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_008262:22424322242432226666224231Clostridium perfringens SM101, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_008262:28245032824503284819823696Clostridium perfringens SM101, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_008262:67711*677119109923389Clostridium perfringens SM101, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_015474:723553*72355378401560463Pyrococcus sp. NA2 chromosome, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_009135:494949*49494951848723539Methanococcus maripaludis C5, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_005791:1028500*1028500105154523046Methanococcus maripaludis S2, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_013741:1390823*1390823141480423982Archaeoglobus profundus DSM 5631, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_008262:297960*29796032314425185Clostridium perfringens SM101, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_015847:1119666*1119666114458724922Methanococcus maripaludis XI chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_014209:2257316*2257316228561028295Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,9e-0969.9BLASTN svgBLASTP svg
NC_012883:1603744*1603744162651022767Thermococcus sibiricus MM 739, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_009975:1500978*1500978152309922122Methanococcus maripaludis C6, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_008262:24980002498000252144223443Clostridium perfringens SM101, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_013921:23759002375900240259926700Thermoanaerobacter italicus Ab9 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014538:23965592396559242259926041Thermoanaerobacter sp. X513 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_015216:40565740565742827422618Methanobacterium sp. AL-21 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008261:576923*57692359692520003Clostridium perfringens ATCC 13124, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_000868:1730820*1730820175956428745Pyrococcus abyssi GE5, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_003106:1435295*1435295145619720903Sulfolobus tokodaii str. 7, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_003366:64908*6490811367548768Clostridium perfringens str. 13, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_008262:101731*10173112528023550Clostridium perfringens SM101, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_009785:13025213025215263622385Streptococcus gordonii str. Challis substr. CH1, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015435:310406*31040632990319498Metallosphaera cuprina Ar-4 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_019791:1189908*1189908121234522438Caldisphaera lagunensis DSM 15908 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_008262:20256992025699204408118383Clostridium perfringens SM101, complete genome9e-0660BLASTN svgBLASTP svg
NC_005877:509877*50987753290123025Picrophilus torridus DSM 9790, complete genome9e-0660BLASTN svgBLASTP svg