Pre_GI: BLASTP Hits

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Query: NC_008262:67711:74407 Clostridium perfringens SM101, complete genome

Start: 74407, End: 75018, Length: 612

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008261:64678:713917139172002612Clostridium perfringens ATCC 13124, complete genomedeoxyguanosine kinase/deoxyadenosine kinase5e-97353
NC_003366:64908:715457154572231687Clostridium perfringens str. 13, complete genomeprobable deoxyguanosine kinase6e-97353
NC_015601:436822:458567458567459226660Erysipelothrix rhusiopathiae str. Fujisawa, complete genomedeoxynucleoside kinase4e-72270
NC_008024:117241:116580116580117269690Streptococcus pyogenes MGAS10750, complete genomeDeoxyadenosine kinase / Deoxyguanosine kinase2e-37155
NC_012470:2021316:204059920405992041240642Streptococcus equi subsp. zooepidemicus, complete genomedeoxynucleoside kinase protein3e-37154
NC_016751:142237:155560155560156195636Marinitoga piezophila KA3 chromosome, complete genomedeoxynucleoside kinase6e-34143
NC_018665:1:241922419224869678Exiguobacterium antarcticum B7 chromosome, complete genomeDeoxyadenosine/deoxycytidine kinase2e-33141
NC_010556:6612:242382423824915678Exiguobacterium sibiricum 255-15, complete genomedeoxynucleoside kinase2e-33141
NC_017353:2353665:236905523690552369729675Staphylococcus lugdunensis N920143, complete genomeputative deoxyadenosine kinase protein4e-31134
NC_013893:2373730:239154123915412392215675Staphylococcus lugdunensis HKU09-01 chromosome, complete genomeDeoxyadenosine kinase/Deoxyguanosine kinase4e-31134
NC_010079:607000:607846607846608508663Staphylococcus aureus subsp. aureus USA300_TCH1516, completedeoxynucleoside kinase3e-30131
NC_007793:606500:607304607304607966663Staphylococcus aureus subsp. aureus USA300, complete genomedeoxynucleoside kinase family protein3e-30131
NC_002951:623461:628737628737629399663Staphylococcus aureus subsp. aureus COL, complete genomedeoxynucleoside kinase family protein3e-30131
NC_007795:541783:543908543908544570663Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein3e-30131
NC_009641:597000:597826597826598488663Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein3e-30131
NC_016912:541500:543904543904544566663Staphylococcus aureus subsp. aureus VC40 chromosome, completedeoxynucleoside kinase family protein3e-30131
NC_017341:618649:620774620774621436663Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,deoxynucleoside kinase3e-30131
NC_017347:616000:616843616843617505663Staphylococcus aureus subsp. aureus T0131 chromosome, completeDeoxynucleoside kinase3e-30131
NC_002952:610462:612588612588613250663Staphylococcus aureus subsp. aureus MRSA252, complete genomeputative deoxyadenosine kinase protein7e-30130
NC_002758:622000:625619625619626281663Staphylococcus aureus subsp. aureus Mu50, complete genomedeoxypurine kinase7e-30130
NC_003923:591000:591932591932592594663Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein7e-30130
NC_002953:588437:590563590563591225663Staphylococcus aureus subsp. aureus MSSA476, complete genomeputative deoxyadenosine kinase protein7e-30130
NC_002745:597947:601373601373602035663Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein7e-30130
NC_009487:636616:641896641896642558663Staphylococcus aureus subsp. aureus JH9 chromosome, completedeoxynucleoside kinase7e-30130
NC_009632:640973:641772641772642434663Staphylococcus aureus subsp. aureus JH1 chromosome, completedeoxynucleoside kinase7e-30130
NC_013450:557109:562386562386563048663Staphylococcus aureus subsp. aureus ED98, complete genomedeoxynucleoside kinase family protein7e-30130
NC_017342:2733215:275090627509062751568663Staphylococcus aureus subsp. aureus TCH60 chromosome, completedeoxynucleoside kinase7e-30130
NC_017343:566000:566901566901567563663Staphylococcus aureus subsp. aureus ECT-R 2, complete genomedeoxynucleoside kinase family protein7e-30130
NC_017351:596000:599439599439600101663Staphylococcus aureus subsp. aureus 11819-97 chromosome, completedeoxyadenosine/deoxycytidine kinase7e-30130
NC_014171:1:225622256223230669Bacillus thuringiensis BMB171 chromosome, complete genomedeoxyguanosine kinase7e-30130
NC_014976:2231984:223451222345122235165654Bacillus subtilis BSn5 chromosome, complete genomedeoxyadenosine/deoxycytidine kinase4e-30130
NC_016928:589223:591348591348592010663Staphylococcus aureus subsp. aureus M013 chromosome, completeDeoxyadenosine kinase /Deoxyguanosine kinase2e-29129
NC_007622:567500:569917569917570579663Staphylococcus aureus RF122, complete genomedeoxypurine kinase subunit1e-29129
NC_017337:610000:613570613570614232663Staphylococcus aureus subsp. aureus ED133 chromosome, completedeoxynucleoside kinase family protein1e-29129
NC_016941:574899:580193580193580855663Staphylococcus aureus subsp. aureus MSHR1132, complete genomeputative deoxyadenosine kinase protein7e-29126
NC_011567:1:231982319823866669Anoxybacillus flavithermus WK1, complete genomeDeoxyadenosine/deoxycytidine kinase1e-28125
NC_014639:1894500:191568719156871916343657Bacillus atrophaeus 1942 chromosome, complete genomedeoxyguanosIne kinase6e-28124
CP002207:1894500:191568719156871916343657Bacillus atrophaeus 1942, complete genomedeoxyguanosIne kinase6e-28124
NC_014761:1588755:159423415942341594860627Oceanithermus profundus DSM 14977 chromosome, complete genomedeoxynucleoside kinase3e-26118
NC_017208:1:223402234022927588Bacillus thuringiensis serovar chinensis CT-43 chromosome, completedeoxyguanosine kinase6e-25114
NC_014219:2284000:230211623021162302802687Bacillus selenitireducens MLS10 chromosome, complete genomedeoxynucleoside kinase3e-24111
NC_010556:6612:249122491225541630Exiguobacterium sibiricum 255-15, complete genomedeoxynucleoside kinase5e-22103
NC_018665:1:248662486625495630Exiguobacterium antarcticum B7 chromosome, complete genomeDeoxyguanosine kinase5e-21100
NC_007947:621213:622016622016622663648Methylobacillus flagellatus KT, complete genomedeoxynucleoside kinase4e-2098.2
NC_016616:1534983:153498315349831535657675Dechlorosoma suillum PS chromosome, complete genomedeoxynucleoside kinase2e-1995.9
NC_014219:2284000:230143223014322302085654Bacillus selenitireducens MLS10 chromosome, complete genomedeoxynucleoside kinase9e-1993.2
NC_011567:1:238632386324501639Anoxybacillus flavithermus WK1, complete genomeDeoxyguanosine kinase1e-1892.8
NC_007633:696604:713285713285713902618Mycoplasma capricolum subsp. capricolum ATCC 27343, completenucleoside kinase2e-1892.4
NC_014761:1588755:159362615936261594225600Oceanithermus profundus DSM 14977 chromosome, complete genomedeoxynucleoside kinase1e-1789.7
NC_014976:2231984:223516222351622235785624Bacillus subtilis BSn5 chromosome, complete genomedeoxyguanosine kinase2e-1789.4
NC_007622:567500:570572570572571189618Staphylococcus aureus RF122, complete genomedeoxypurine kinase subunit6e-1787.4
NC_017353:2353665:236844523684452369062618Staphylococcus lugdunensis N920143, complete genomeputative deoxyadenosine kinase protein8e-1787
NC_013893:2373730:239093123909312391548618Staphylococcus lugdunensis HKU09-01 chromosome, complete genomeDeoxyadenosine kinase/Deoxyguanosine kinase8e-1787
NC_017341:618649:621429621429622076648Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,deoxynucleoside kinase1e-1686.3
NC_010079:607000:608501608501609163663Staphylococcus aureus subsp. aureus USA300_TCH1516, completedeoxynucleoside kinase2e-1685.9
NC_009641:597000:598481598481599143663Staphylococcus aureus subsp. aureus str. Newman chromosome,deoxynucleoside kinase2e-1685.9
NC_017342:2733215:275026627502662750913648Staphylococcus aureus subsp. aureus TCH60 chromosome, completedeoxynucleoside kinase2e-1685.9
NC_002951:623461:629392629392630009618Staphylococcus aureus subsp. aureus COL, complete genomedeoxynucleoside kinase family protein2e-1685.9
NC_002952:610462:613243613243613860618Staphylococcus aureus subsp. aureus MRSA252, complete genomeputative deoxyadenosine kinase protein2e-1685.9
NC_003923:591000:592587592587593204618Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein2e-1685.9
NC_007793:606500:607959607959608576618Staphylococcus aureus subsp. aureus USA300, complete genomedeoxynucleoside kinase family protein2e-1685.9
NC_007795:541783:544563544563545180618Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein2e-1685.9
NC_002953:588437:591218591218591835618Staphylococcus aureus subsp. aureus MSSA476, complete genomeputative deoxyadenosine kinase protein2e-1685.9
NC_016912:541500:544559544559545176618Staphylococcus aureus subsp. aureus VC40 chromosome, completedeoxyguanosine kinase2e-1685.9
NC_016928:589223:592003592003592620618Staphylococcus aureus subsp. aureus M013 chromosome, completeDeoxyadenosine kinase /Deoxyguanosine kinase2e-1685.9
NC_017337:610000:614225614225614842618Staphylococcus aureus subsp. aureus ED133 chromosome, completedeoxynucleoside kinase family protein2e-1685.9
NC_017347:616000:617498617498618115618Staphylococcus aureus subsp. aureus T0131 chromosome, completeDeoxynucleoside kinase2e-1685.9
NC_002745:597947:602028602028602645618Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein2e-1685.5
NC_002758:622000:626274626274626891618Staphylococcus aureus subsp. aureus Mu50, complete genomesimilar to deoxypurine kinase2e-1685.5
NC_013450:557109:563041563041563658618Staphylococcus aureus subsp. aureus ED98, complete genomedeoxynucleoside kinase family protein2e-1685.5
NC_017343:566000:567556567556568173618Staphylococcus aureus subsp. aureus ECT-R 2, complete genomedeoxynucleoside kinase family protein2e-1685.5
NC_017351:596000:600094600094600711618Staphylococcus aureus subsp. aureus 11819-97 chromosome, completedeoxyguanosine kinase2e-1685.5
NC_009487:636616:642551642551643213663Staphylococcus aureus subsp. aureus JH9 chromosome, completedeoxynucleoside kinase2e-1685.5
NC_009632:640973:642427642427643089663Staphylococcus aureus subsp. aureus JH1 chromosome, completedeoxynucleoside kinase2e-1685.5
NC_016941:574899:580848580848581465618Staphylococcus aureus subsp. aureus MSHR1132, complete genomeputative deoxyadenosine kinase protein3e-1684.7
NC_007951:570500:571617571617572297681Burkholderia xenovorans LB400 chromosome 1, complete sequencePutative deoxynucleoside kinase6e-1684
NC_014171:1:232332323323868636Bacillus thuringiensis BMB171 chromosome, complete genomedeoxyguanosine kinase1e-1582.8
NC_017208:1:230112301123646636Bacillus thuringiensis serovar chinensis CT-43 chromosome, completedeoxyguanosine kinase2e-1582.4
NC_016751:142237:156195156195156815621Marinitoga piezophila KA3 chromosome, complete genomedeoxynucleoside kinase1e-0962.8
NC_016944:1621575:163612816361281636721594Vibrio cholerae IEC224 chromosome I, complete sequencedeoxyribonucleoside kinase1e-0859.7
NC_019940:929071:9381679381679394531287Thioflavicoccus mobilis 8321 chromosome, complete genomedeoxynucleoside kinase2e-0858.9