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Query: NC_008261:2524913 Clostridium perfringens ATCC 13124, complete genome

Start: 2524913, End: 2542599, Length: 17687

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: The species type strain, originally isolated from a human gas gangrene patient. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_020291:1014333*1014333103759923267Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome0971BLASTN svgBLASTP svg
NC_008593:1704207*1704207172452320317Clostridium novyi NT, complete genome0882BLASTN svgBLASTP svg
NC_010520:3204480*3204480322378019301Clostridium botulinum A3 str. Loch Maree, complete genome0670BLASTN svgBLASTP svg
NC_010516:3196158*3196158321545819301Clostridium botulinum B1 str. Okra, complete genome0654BLASTN svgBLASTP svg
NC_012563:3374904*3374904339859023687Clostridium botulinum A2 str. Kyoto, complete genome0646BLASTN svgBLASTP svg
NC_021182:2192718*2192718221646323746Clostridium pasteurianum BC1, complete genome3e-101377BLASTN svgBLASTP svg
NC_006274:4159096*4159096417709918004Bacillus cereus E33L, complete genome2e-31145BLASTN svgBLASTP svg
NC_008600:4101748*4101748412497023223Bacillus thuringiensis str. Al Hakam, complete genome2e-31145BLASTN svgBLASTP svg
NC_012472:4119192*4119192414241423223Bacillus cereus 03BB102, complete genome2e-31145BLASTN svgBLASTP svg
NC_014335:4027105*4027105404657819474Bacillus cereus biovar anthracis str. CI chromosome, complete1e-26129BLASTN svgBLASTP svg
NC_007530:4117071*4117071413809921029Bacillus anthracis str. 'Ames Ancestor', complete genome1e-26129BLASTN svgBLASTP svg
NC_005957:4104880*4104880412588721008Bacillus thuringiensis serovar konkukian str. 97-27, complete1e-26129BLASTN svgBLASTP svg
NC_005945:4116978*4116978413524218265Bacillus anthracis str. Sterne, complete genome1e-26129BLASTN svgBLASTP svg
NC_003997:4116944*4116944413809921156Bacillus anthracis str. Ames, complete genome1e-26129BLASTN svgBLASTP svg
NC_010001:2836995*2836995286257025576Clostridium phytofermentans ISDg, complete genome7e-25123BLASTN svgBLASTP svg
NC_011772:4255161*4255161427769522535Bacillus cereus G9842, complete genome4e-23117BLASTN svgBLASTP svg
NC_003909:4064904*4064904408337118468Bacillus cereus ATCC 10987, complete genome6e-22113BLASTN svgBLASTP svg
NC_010184:4155345*4155345417709921755Bacillus weihenstephanensis KBAB4, complete genome1e-20109BLASTN svgBLASTP svg
NC_004722:4244730*4244730426728722558Bacillus cereus ATCC 14579, complete genome1e-20109BLASTN svgBLASTP svg
NC_015760:123929*12392914613122203Streptococcus salivarius CCHSS3, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_011047:255208*25520828174126534Candidatus Phytoplasma mali, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_007622:1558753*1558753157743218680Staphylococcus aureus RF122, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_011999:1320159*1320159133954619388Macrococcus caseolyticus JCSC5402, complete genome9e-1589.7BLASTN svgBLASTP svg
NC_002528:148274*14827417635828085Buchnera aphidicola str. APS (Acyrthosiphon pisum), complete4e-1487.7BLASTN svgBLASTP svg
NC_004061:146862*14686216626919408Buchnera aphidicola str. Sg (Schizaphis graminum), complete genome4e-1487.7BLASTN svgBLASTP svg
NC_010611:31976*319765159919624Acinetobacter baumannii ACICU, complete genome1e-1385.7BLASTN svgBLASTP svg
NC_013517:82510082510084990924810Sebaldella termitidis ATCC 33386, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_013515:14834711483471150341619946Streptobacillus moniliformis DSM 12112, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_006449:121462*12146214259721136Streptococcus thermophilus CNRZ1066, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_013123:78786*7878610552026735Candidatus Sulcia muelleri SMDSEM, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_013454:229587*22958725413424548Blattabacterium sp. (Blattella germanica) str. Bge, complete2e-1281.8BLASTN svgBLASTP svg
NC_014150:1*11978219782Brachyspira murdochii DSM 12563 chromosome, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_014499:87528*8752810905021523Candidatus Sulcia muelleri CARI chromosome, complete genome3e-1177.8BLASTN svgBLASTP svg
NC_012225:236490*23649025991523426Brachyspira hyodysenteriae WA1, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_009850:2169459*2169459220320233744Arcobacter butzleri RM4018, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_006448:121435*12143514257121137Streptococcus thermophilus LMG 18311, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_012925:27570427570429851422811Streptococcus suis P1/7, complete genome5e-1073.8BLASTN svgBLASTP svg
NC_014004:66631*666318870622076Candidatus Sulcia muelleri DMIN chromosome, complete genome5e-1073.8BLASTN svgBLASTP svg
NC_015662:110950*11095013012219173Buchnera aphidicola (Cinara tujafilina) chromosome, complete2e-0971.9BLASTN svgBLASTP svg
NC_014751:449001*44900146805619056Mycoplasma leachii PG50 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_014721:1629063*1629063165209923037Caldicellulosiruptor kristjanssonii 177R1B chromosome, complete9e-0969.9BLASTN svgBLASTP svg
NC_005303:780557*78055780913328577Onion yellows phytoplasma OY-M, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_000963:20554620554622772522180Rickettsia prowazekii str. Madrid E, complete genome3e-0867.9BLASTN svgBLASTP svg
NC_006833:637964*63796465659918636Wolbachia endosymbiont strain TRS of Brugia malayi, complete3e-0867.9BLASTN svgBLASTP svg
NC_003869:94800094800097076722768Thermoanaerobacter tengcongensis MB4, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_018515:4148037*4148037416623318197Desulfosporosinus meridiei DSM 13257 chromosome, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_004545:141478*14147816560324126Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genome5e-0763.9BLASTN svgBLASTP svg
NC_009012:1595498*1595498161817522678Clostridium thermocellum ATCC 27405, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014758:245707*24570726409918393Calditerrivibrio nitroreducens DSM 19672 chromosome, complete2e-0661.9BLASTN svgBLASTP svg
NC_018507:339000*33900036299924000Candidatus Portiera aleyrodidarum BT-B chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_018677:329829*32982935599926171Candidatus Portiera aleyrodidarum BT-B-HRs chromosome, complete2e-0661.9BLASTN svgBLASTP svg
NC_020291:4357425*4357425438031722893Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-0661.9BLASTN svgBLASTP svg
NC_020195:234392*23439225309918708Blattabacterium sp. (Blatta orientalis) str. Tarazona, complete8e-0660BLASTN svgBLASTP svg
NC_015574:23228112322811234307020260Methanobacterium sp. SWAN-1 chromosome, complete genome8e-0660BLASTN svgBLASTP svg
NC_013061:717752*71775274137623625Pedobacter heparinus DSM 2366, complete genome8e-0660BLASTN svgBLASTP svg
NC_002620:803696*80369682802824333Chlamydia muridarum Nigg, complete genome8e-0660BLASTN svgBLASTP svg