Pre_GI: BLASTP Hits

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Query: NC_008261:676000:692458 Clostridium perfringens ATCC 13124, complete genome

Start: 692458, End: 692988, Length: 531

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: The species type strain, originally isolated from a human gas gangrene patient. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003366:728859:745148745148745678531Clostridium perfringens str. 13, complete genomeprobable signal peptidase type I1e-88325
NC_008262:654000:670657670657671187531Clostridium perfringens SM101, complete genomesignal peptidase I1e-87322
NC_016012:104500:116248116248116961714Candidatus Arthromitus sp. SFB-rat-Yit, complete genomesignal peptidase I5e-40163
NC_020291:5808856:582730858273085827901594Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomesignal peptidase I2e-39161
NC_008699:1673181:171900117190011719441441Nocardioides sp. JS614, complete genome1e-26119
NC_014410:8694:267012670127237537Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,signal peptidase I3e-22104
NC_019970:8938:269582695827494537Thermoanaerobacterium thermosaccharolyticum M0795, complete genomesignal peptidase I6e-22103
NC_015958:11511:295512955130081531Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomesignal peptidase I6e-22103
NC_003869:14153:279792797928521543Thermoanaerobacter tengcongensis MB4, complete genomeSignal peptidase I5e-22103
NC_019757:1309766:131088013108801311452573Cylindrospermum stagnale PCC 7417, complete genomesignal peptidase I1e-21102
NC_008312:3385930:340198834019883402638651Trichodesmium erythraeum IMS101, complete genomesignal peptidase I3e-2098.2
NC_011297:1357947:136038813603881360951564Dictyoglomus thermophilum H-6-12, complete genomesignal peptidase I3e-2097.8
NC_011661:1542335:154477615447761545339564Dictyoglomus turgidum DSM 6724, complete genomesignal peptidase I7e-2096.7
NC_014844:903877:923984923984924601618Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomesignal peptidase I2e-1994.7
NC_011830:2901346:291932629193262919895570Desulfitobacterium hafniense DCB-2, complete genomesignal peptidase I3e-1994.4
NC_010382:1607013:162370816237081624271564Lysinibacillus sphaericus C3-41, complete genomeSignal peptidase I1e-1892.4
NC_009925:3164766:316818031681803168788609Acaryochloris marina MBIC11017, complete genomesignal peptidase I2e-1891.7
NC_014960:2141345:215951121595112160107597Anaerolinea thermophila UNI-1, complete genomesignal peptidase I6e-1890.5
NC_017277:96325:986099860999199591Synechocystis sp. PCC 6803, complete genomeleader peptidase I1e-1789.4
NC_017052:96325:986099860999199591Synechocystis sp. PCC 6803 substr. PCC-N, complete genomeleader peptidase I1e-1789.4
NC_017039:96325:986099860999199591Synechocystis sp. PCC 6803 substr. PCC-P, complete genomeleader peptidase I1e-1789.4
NC_000911:96325:986099860999199591Synechocystis sp. PCC 6803, complete genomeleader peptidase I1e-1789.4
NC_009925:3164766:316738531673853168059675Acaryochloris marina MBIC11017, complete genomesignal peptidase I2e-1788.6
NC_004668:2938000:294276929427692943305537Enterococcus faecalis V583, complete genomesignal peptidase I2e-1788.6
NC_017316:2466244:247087524708752471411537Enterococcus faecalis OG1RF chromosome, complete genomesignal peptidase I LepB5e-1787.4
NC_007519:2773000:280191428019142802576663Desulfovibrio alaskensis G20 chromosome, complete genomesignal peptidase I6e-1787
NC_009706:2925000:292536629253662925896531Clostridium kluyveri DSM 555 chromosome, complete genomesignal peptidase5e-1787
NC_011837:2856500:285686828568682857398531Clostridium kluyveri NBRC 12016, complete genomehypothetical protein5e-1787
NC_016593:868500:871729871729872286558Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completeSignal peptidase I2e-1685.1
NC_009328:2083386:209322820932282093785558Geobacillus thermodenitrificans NG80-2 chromosome, complete genomeType I signal peptidase2e-1685.1
NC_014624:2668157:267015626701562670695540Eubacterium limosum KIST612 chromosome, complete genomesignal peptidase I3e-1684.3
NC_016584:4860360:487726148772614877785525Desulfosporosinus orientis DSM 765 chromosome, complete genomesignal peptidase I3e-1684.3
NC_014650:2943975:294621129462112946768558Geobacillus sp. Y4.1MC1 chromosome, complete genomesignal peptidase I5e-1684
NC_013216:1219775:122165012216501222210561Desulfotomaculum acetoxidans DSM 771, complete genomesignal peptidase I4e-1684
NC_016629:1111619:114657311465731147172600Desulfovibrio africanus str. Walvis Bay chromosome, completesignal peptidase I8e-1683.2
NC_012560:1322000:133760413376041338455852Azotobacter vinelandii DJ, complete genomesignal peptidase I2e-1581.6
NC_021150:1322000:133761613376161338467852Azotobacter vinelandii CA6, complete genomesignal peptidase I2e-1581.6
NC_014976:403919:409368409368409922555Bacillus subtilis BSn5 chromosome, complete genometype I signal peptidase4e-1580.9
NC_016109:5768000:577346257734625774208747Kitasatospora setae KM-6054, complete genomeputative signal peptidase I4e-1580.9
NC_017195:2273216:227764122776412278195555Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completesignal peptidase I5e-1580.5
NC_009495:2571732:257729925772992577823525Clostridium botulinum A str. ATCC 3502 chromosome, complete genomesignal peptidase I5e-1580.5
NC_011769:3434744:344232334423233442919597Desulfovibrio vulgaris str. 'Miyazaki F', complete genomesignal peptidase I5e-1580.5
NC_009698:2420484:242166624216662422190525Clostridium botulinum A str. Hall chromosome, complete genomesignal peptidase I8e-1579.7
NC_010520:2635750:264031626403162640840525Clostridium botulinum A3 str. Loch Maree, complete genomesignal peptidase I1e-1479.3
NC_014643:1986440:1996064199606419971821119Rothia dentocariosa ATCC 17931 chromosome, complete genomesignal peptidase I LepB family protein1e-1479.3
NC_018515:3865522:388200838820083882532525Desulfosporosinus meridiei DSM 13257 chromosome, complete genomesignal peptidase I1e-1479.3
UCMB5137:1834999:183773518377351838289555Bacillus atrophaeus UCMB-5137type I signal peptidase2e-1479
NC_010184:3713359:371427037142703714821552Bacillus weihenstephanensis KBAB4, complete genomesignal peptidase I2e-1478.6
NC_011725:2949519:296233229623322962883552Bacillus cereus B4264 chromosome, complete genomeSignal peptidase I U2e-1478.2
NC_017208:3816753:385560938556093856160552Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeSignal peptidase I6e-1477
NC_010184:1114000:111755611175561118119564Bacillus weihenstephanensis KBAB4, complete genomesignal peptidase I6e-1477
NC_014171:3726054:373947637394763740027552Bacillus thuringiensis BMB171 chromosome, complete genomesignal peptidase I6e-1477
NC_011772:3821917:382593438259343826485552Bacillus cereus G9842, complete genomesignal peptidase I S6e-1477
NC_013198:298000:302960302960303559600Lactobacillus rhamnosus GG, complete genomesignal peptidase I / leader peptidase I (SpaseI)1e-1376.3
NC_013199:282901:284998284998285597600Lactobacillus rhamnosus Lc 705, complete genomesignal peptidase I (Leader peptidase I, SpaseI)1e-1376.3
NC_014644:1456689:148568014856801486264585Gardnerella vaginalis ATCC 14019 chromosome, complete genomesignal peptidase I LepB1e-1376.3
NC_011725:1150779:115835711583571158920564Bacillus cereus B4264 chromosome, complete genomesignal peptidase I1e-1375.9
NC_016627:3205333:323277432327743233325552Clostridium clariflavum DSM 19732 chromosome, complete genomesignal peptidase I1e-1375.9
NC_003909:1244000:125066012506601251223564Bacillus cereus ATCC 10987, complete genomesignal peptidase I2e-1375.5
NC_011969:1181302:118763811876381188201564Bacillus cereus Q1 chromosome, complete genomesignal peptidase i2e-1375.5
NC_004722:1108649:111629911162991116862564Bacillus cereus ATCC 14579, complete genomeSignal peptidase I2e-1375.5
NC_014335:3589726:360634936063493606900552Bacillus cereus biovar anthracis str. CI chromosome, completesignal peptidase I S2e-1375.5
NC_003997:3617000:365549536554953656046552Bacillus anthracis str. Ames, complete genomesignal peptidase I S2e-1375.5
NC_005945:3636321:365619036561903656741552Bacillus anthracis str. Sterne, complete genomesignal peptidase I S2e-1375.5
NC_007530:3616828:365562236556223656173552Bacillus anthracis str. 'Ames Ancestor', complete genomesignal peptidase i s2e-1375.5
NC_005957:3665657:367716836771683677719552Bacillus thuringiensis serovar konkukian str. 97-27, completesignal peptidase I S2e-1375.5
NC_003909:3606177:363089336308933631444552Bacillus cereus ATCC 10987, complete genomesignal peptidase I S2e-1375.5
NC_011658:3603009:364354036435403644091552Bacillus cereus AH187 chromosome, complete genomesignal peptidase I S2e-1375.5
NC_011969:3575988:358750135875013588052552Bacillus cereus Q1 chromosome, complete genomesignal peptidase i s2e-1375.5
NC_012581:559182:582514582514583065552Bacillus anthracis str. CDC 684 chromosome, complete genomesignal peptidase I S2e-1375.5
NC_012659:3617000:365552236555223656073552Bacillus anthracis str. A0248, complete genomesignal peptidase I S2e-1375.5
NC_014335:1094000:110111011011101101673564Bacillus cereus biovar anthracis str. CI chromosome, completesignal peptidase I2e-1375.1
NC_011772:1094534:110225911022591102822564Bacillus cereus G9842, complete genomesignal peptidase I2e-1375.1
NC_017208:1147230:115484811548481155411564Bacillus thuringiensis serovar chinensis CT-43 chromosome, completesignal peptidase I2e-1375.1
NC_014171:1118000:112415311241531124716564Bacillus thuringiensis BMB171 chromosome, complete genomesignal peptidase I2e-1375.1
NC_005945:1103729:111135111113511111914564Bacillus anthracis str. Sterne, complete genomesignal peptidase I4e-1374.3
NC_012659:1103737:111135911113591111922564Bacillus anthracis str. A0248, complete genomesignal peptidase I4e-1374.3
NC_014844:2638994:264007526400752640941867Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomesignal peptidase I4e-1374.3
NC_011773:3689473:369038436903843690935552Bacillus cereus AH820 chromosome, complete genomesignal peptidase I S3e-1374.3
NC_014972:3604534:363116036311603631810651Desulfobulbus propionicus DSM 2032 chromosome, complete genomesignal peptidase I5e-1373.9
NC_011725:2949519:295210229521022952623522Bacillus cereus B4264 chromosome, complete genomesignal peptidase I8e-1373.2
NC_014829:1526401:154242015424201543013594Bacillus cellulosilyticus DSM 2522 chromosome, complete genomesignal peptidase I9e-1373.2
NC_020134:1328302:133088913308891331500612Clostridium stercorarium subsp. stercorarium DSM 8532, completesignal peptidase LepB1e-1272.8
NC_010572:2216309:223091322309132231668756Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative signal peptidase I1e-1272.8
NC_013894:672840:704067704067704747681Thermocrinis albus DSM 14484 chromosome, complete genomesignal peptidase I3e-1271.6
NC_014328:1379437:139177213917721392296525Clostridium ljungdahlii ATCC 49587 chromosome, complete genomesignal peptidase I5e-1270.5
NC_014973:493500:513272513272514147876Geobacter sp. M18 chromosome, complete genomesignal peptidase I6e-1270.5
NC_015759:760671:778705778705779331627Weissella koreensis KACC 15510 chromosome, complete genomesignal peptidase I7e-1270.1
NC_010572:2216309:2232515223251522335911077Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative signal peptidase I8e-1269.7
NC_014483:1973233:198332719833271983953627Paenibacillus polymyxa E681 chromosome, complete genomeSignal peptidase I (SPase I) (Leader peptidase I)9e-1269.7
NC_018867:677848:680897680897681430534Dehalobacter sp. CF chromosome, complete genomeSignal peptidase I1e-1169.3
NC_018866:611588:616453616453616986534Dehalobacter sp. DCA chromosome, complete genomeSignal peptidase I1e-1169.3
NC_014973:595153:606647606647607522876Geobacter sp. M18 chromosome, complete genomesignal peptidase I2e-1168.9
NC_007103:198500:204596204596205144549Bacillus cereus E33L plasmid pE33L466, complete sequencesignal peptidase I2e-1168.2
NC_015977:2565922:257362125736212574172552Roseburia hominis A2-183 chromosome, complete genomesignal peptidase I LepB55e-1167
NC_008526:250000:254726254726255325600Lactobacillus casei ATCC 334, complete genomeSignal peptidase I1e-1066.2
NC_005295:647275:651950651950652666717Ehrlichia ruminantium str. Welgevonden, complete genomeprokaryotic type I signal peptidase1e-1066.2
NC_006831:622906:627646627646628362717Ehrlichia ruminantium str. Gardel, complete genomeSignal peptidase I1e-1066.2
NC_006832:627057:631795631795632511717Ehrlichia ruminantium str. Welgevonden, complete genomeSignal peptidase I1e-1066.2
NC_010999:252605:254091254091254690600Lactobacillus casei, complete genomeType I signal peptidase-like protein1e-1066.2
NC_014334:267409:271659271659272258600Lactobacillus casei str. Zhang chromosome, complete genomesignal peptidase I1e-1066.2
NC_007354:534865:541126541126541836711Ehrlichia canis str. Jake, complete genomeSignal peptidase I1e-1066.2
NC_012438:192065:197769197769198479711Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomesignal peptidase I1e-1066.2
NC_016047:1234743:123536812353681235874507Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completesignal peptidase I2e-1065.5
NC_014643:1986440:199532619953261995958633Rothia dentocariosa ATCC 17931 chromosome, complete genomesignal peptidase I LepB2e-1065.1
NC_012440:585568:593978593978594679702Persephonella marina EX-H1, complete genomesignal peptidase I3e-1064.7
NC_007799:686358:699396699396700103708Ehrlichia chaffeensis str. Arkansas, complete genomesignal peptidase I4e-1064.3
NC_010572:2216309:223171922317192232612894Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative signal peptidase I4e-1063.9
NC_014318:6108633:611349161134916114426936Amycolatopsis mediterranei U32 chromosome, complete genomesignal peptidase I6e-1063.5
NC_017186:6108676:611353461135346114469936Amycolatopsis mediterranei S699 chromosome, complete genomesignal peptidase I6e-1063.5
NC_015737:1385585:139346913934691394131663Clostridium sp. SY8519, complete genomehypothetical protein8e-1063.2
NC_003454:983681:999062999062999922861Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeSignal peptidase I8e-1063.2
NC_016109:5768000:5771111577111157721721062Kitasatospora setae KM-6054, complete genomeputative signal peptidase I1e-0962.8
NC_018528:2034000:204897020489702049611642Lactobacillus helveticus R0052 chromosome, complete genomeSignal peptidase I1e-0962.4
NC_014172:53815:582175821758642426Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequenceSignal peptidase I1e-0962.4
NC_018643:641360:642022642022642759738Alpha proteobacterium HIMB5 chromosome, complete genomesignal peptidase I2e-0962
NC_007298:2170181:218023621802362181024789Dechloromonas aromatica RCB, complete genomePeptidase S26A, signal peptidase I3e-0961.6
NC_012489:4336790:435245143524514353344894Gemmatimonas aurantiaca T-27, complete genomeputative signal peptidase I2e-0961.6
NC_012491:3736167:374708937470893747589501Brevibacillus brevis NBRC 100599, complete genomesignal peptidase I2e-0961.6
NC_016109:5768000:577237757723775773291915Kitasatospora setae KM-6054, complete genomeputative signal peptidase I4e-0961.2
NC_017300:1426975:143845314384531439268816Corynebacterium pseudotuberculosis 1002 chromosome, completeSignal peptidase I4e-0961.2
NC_017301:1425293:144084114408411441656816Corynebacterium pseudotuberculosis C231 chromosome, completeSignal peptidase I4e-0961.2
NC_014329:1407880:144109514410951441856762Corynebacterium pseudotuberculosis FRC41 chromosome, completesignal peptidase I3e-0961.2
NC_016932:1414226:142569914256991426460762Corynebacterium pseudotuberculosis 316 chromosome, complete genomeSignal peptidase I3e-0961.2
NC_006322:1119471:112174711217471122265519Bacillus licheniformis ATCC 14580, complete genomeSipV5e-0960.5
NC_006270:1119000:112089311208931121411519Bacillus licheniformis ATCC 14580, complete genometype I signal peptidase5e-0960.5
NC_002935:1534889:153917715391771540034858Corynebacterium diphtheriae NCTC 13129, complete genomePutative signal peptidase2e-0858.9
NC_016787:1509831:151907015190701519990921Corynebacterium diphtheriae HC03 chromosome, complete genomesignal peptidase I2e-0858.5
NC_016788:1509943:152253515225351523455921Corynebacterium diphtheriae HC04 chromosome, complete genomesignal peptidase I2e-0858.5
NC_016790:1480441:149503014950301495950921Corynebacterium diphtheriae VA01 chromosome, complete genomesignal peptidase I3e-0857.8
NC_016786:1519481:152776815277681528688921Corynebacterium diphtheriae HC01 chromosome, complete genomesignal peptidase I3e-0857.8
NC_016782:1520324:152750315275031528423921Corynebacterium diphtheriae 241 chromosome, complete genomesignal peptidase I3e-0857.8
NC_016109:5768000:577019557701955771127933Kitasatospora setae KM-6054, complete genomeputative signal peptidase I8e-0856.6
NC_012660:165559:178328178328178855528Pseudomonas fluorescens SBW25 chromosome, complete genomeputative signal peptidase3e-0754.3
NC_005125:3420270:342295834229583423455498Gloeobacter violaceus PCC 7421, complete genomeprobable signal peptidase4e-0754.3
NC_015978:1266196:128821812882181288853636Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein8e-0753.1
NC_012806:818592:824993824993825331339Mycoplasma conjunctivae, complete genomeputative Signal peptidase I5e-0650.4