Pre_GI: BLASTP Hits

Some Help

Query: NC_008261:1:15074 Clostridium perfringens ATCC 13124, complete genome

Start: 15074, End: 15149, Length: 76

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: The species type strain, originally isolated from a human gas gangrene patient. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008262:2649289:26755392675539267561476Clostridium perfringens SM101, complete genometRNA-Ala9e-0752.4
NC_008261:2770468:27815992781599278167476Clostridium perfringens ATCC 13124, complete genometRNA-Ala9e-0752.4
NC_008262:67711:90758907589083376Clostridium perfringens SM101, complete genometRNA-Ala9e-0752.4
NC_008262:2433979:24450972445097244517276Clostridium perfringens SM101, complete genometRNA-Ala9e-0752.4
NC_003366:2556457:25675942567594256766673Clostridium perfringens str. 13, complete genome3e-0650.4
NC_003366:332500:34072534072534079773Clostridium perfringens str. 13, complete genome3e-0650.4
NC_003366:2556457:25777002577700257777273Clostridium perfringens str. 13, complete genome3e-0650.4
NC_003366:1:15074150741514673Clostridium perfringens str. 13, complete genome3e-0650.4
NC_003366:64908:77685776857775773Clostridium perfringens str. 13, complete genome3e-0650.4
NC_015519:1205049:12184631218463121853876Tepidanaerobacter sp. Re1 chromosome, complete genometRNA-Ala5e-0649.7
NC_009697:1:14202142021427776Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala1e-0548.9
NC_009495:482500:49068349068349075876Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala1e-0548.9
NC_009495:38000:56726567265680176Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala1e-0548.9
NC_009495:3735703:37512513751251375132676Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala1e-0548.9
NC_009495:1:14187141871426276Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Ala1e-0548.9
NC_010376:186510:19940519940519948076Finegoldia magna ATCC 29328, complete genometRNA-Ala1e-0548.9
NC_004557:2777291:27936662793666279374176Clostridium tetani E88, complete genometRNA-Ala1e-0548.9
NC_010376:606000:61336361336361343876Finegoldia magna ATCC 29328, complete genometRNA-Ala1e-0548.9
NC_004557:558500:56665756665756673276Clostridium tetani E88, complete genometRNA-Ala1e-0548.9
NC_009697:3711692:37272403727240372731576Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala1e-0548.9
NC_009697:444801:45562045562045569576Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Ala1e-0548.9
NC_009698:1:14202142021427776Clostridium botulinum A str. Hall chromosome, complete genometRNA-Ala1e-0548.9
NC_017297:490922:50205950205950213476Clostridium botulinum F str. 230613 chromosome, complete genometRNA-Ala1e-0548.9
NC_017297:1:14178141781425376Clostridium botulinum F str. 230613 chromosome, complete genometRNA-Ala1e-0548.9
NC_016627:4871875:48844744884474488454976Clostridium clariflavum DSM 19732 chromosome, complete genometRNA-Ala1e-0548.9
NC_016627:3815690:38274073827407382748276Clostridium clariflavum DSM 19732 chromosome, complete genometRNA-Ala1e-0548.9
NC_009699:490652:50178950178950186476Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala1e-0548.9
NC_009699:3839575:38540443854044385411976Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala1e-0548.9
NC_009699:1:14112141121418776Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Ala1e-0548.9
NC_009698:467500:47600847600847608376Clostridium botulinum A str. Hall chromosome, complete genometRNA-Ala1e-0548.9
NC_009698:3609881:36243493624349362442476Clostridium botulinum A str. Hall chromosome, complete genometRNA-Ala1e-0548.9
NC_020134:2295092:23108792310879231095476Clostridium stercorarium subsp. stercorarium DSM 8532, completetRNA-Ala1e-0548.9