Pre_GI: BLASTP Hits

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Query: NC_008258:269806:288369 Shigella flexneri 5 str. 8401, complete genome

Start: 288369, End: 289715, Length: 1347

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:3674947367494736762931347Shigella flexneri 2002017 chromosome, complete genomeIS4 ORF0919
NC_004337:3590323:3938517393851739398631347Shigella flexneri 2a str. 301, complete genomeIS4 ORF0919
NC_016822:2678691:2678691267869126800371347Shigella sonnei 53G, complete genomeIS4 orf0915
NC_016822:1781644:1784123178412317854691347Shigella sonnei 53G, complete genomeIS4 orf0915
NC_007384:1696831:1711913171191317132591347Shigella sonnei Ss046, complete genomeIS4 ORF0915
NC_007384:2587876:2587876258787625892221347Shigella sonnei Ss046, complete genomeIS4 ORF0913
NC_007384:4095016:4114725411472541160711347Shigella sonnei Ss046, complete genomeIS4 ORF0912
NC_004337:3590323:3917660391766039190061347Shigella flexneri 2a str. 301, complete genomeIS4 ORF0911
NC_011751:4992500:5010215501021550115611347Escherichia coli UMN026 chromosome, complete genomeputative IS4 transposase; KpLE2 phage-like element0910
NC_004741:4132056:4132056413205641333841329Shigella flexneri 2a str. 2457T, complete genomeIS4 orf0909
NC_017328:3935185:3943321394332139446491329Shigella flexneri 2002017 chromosome, complete genomeIS4 ORF0906
NC_000913:4494773:4500126450012645014541329Escherichia coli K12, complete genomeKpLE2 phage-like element; IS4 predicted transposase0899
NC_010473:4596500:4601934460193446032621329Escherichia coli str. K-12 substr. DH10B, complete genomeKpLE2 phage-like element; IS4 predicted transposase0899
AC_000091:4501430:4506783450678345081111329Escherichia coli W3110 DNA, complete genomeIS4 predicted transposase0899
NC_012759:4433500:4438861443886144401891329Escherichia coli BW2952 chromosome, complete genomeKpLE2 phage-like element; IS4 putative transposase0899
NC_012947:3917619:3928785392878539301131329Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completetransposase IS4 family protein0899
NC_012967:4473368:4483995448399544853231329Escherichia coli B str. REL606 chromosome, complete genomeIS4 putative transposase0899
NC_004431:3513147:3532771353277135341201350Escherichia coli CFT073, complete genomeTransposase insG for insertion sequence element IS40886
NC_007613:4119771:4131701413170141330171317Shigella boydii Sb227, complete genomeIS4 ORF0876
NC_017047:4379989:4402292440229244036141323Rahnella aquatilis HX2 chromosome, complete genometransposase IS4 family protein8e-121434
NC_015061:3725921:3730563373056337318851323Rahnella sp. Y9602 chromosome, complete genometransposase IS4 family protein7e-121434
NC_017047:3793000:3795224379522437965461323Rahnella aquatilis HX2 chromosome, complete genometransposase IS4 family protein7e-121434
NC_011312:3060371:3060371306037130616961326Aliivibrio salmonicida LFI1238 chromosome chromosome 1, completetransposase4e-114411
NC_004337:2478461:247846124784612479084624Shigella flexneri 2a str. 301, complete genomeIS4 ORF8e-103374
NC_017328:2516000:251608325160832516706624Shigella flexneri 2002017 chromosome, complete genomeIS4 ORF4e-102372
NC_004741:2456297:245658024565802457185606Shigella flexneri 2a str. 2457T, complete genomeIS4 orf8e-99360
NC_013440:3947493:3961875396187539632241350Haliangium ochraceum DSM 14365, complete genometransposase IS4 family protein7e-73275
NC_013716:5201097:526948252694825269871390Citrobacter rodentium ICC168, complete genome4e-67255
NC_005139:2201820:2256801225680122581381338Vibrio vulnificus YJ016 chromosome I, complete sequencetransposase and inactivated derivative4e-67255
NC_013716:4408201:4408201440820144095381338Citrobacter rodentium ICC168, complete genomeISCro3 transposase3e-66252
NC_012912:242709:2468462468462481711326Dickeya zeae Ech1591, complete genometransposase IS4 family protein2e-64246
NC_012912:1788308:1815719181571918170441326Dickeya zeae Ech1591, complete genometransposase IS4 family protein2e-64246
NC_010625:229478:2380132380132393411329Burkholderia phymatum STM815 plasmid pBPHY01, complete sequencetransposase IS4 family protein6e-64245
NC_012560:3303961:3306480330648033076461167Azotobacter vinelandii DJ, complete genomeTransposase, IS4 protein8e-58224
NC_021150:3303959:3306478330647833076441167Azotobacter vinelandii CA6, complete genomeTransposase, IS4 protein8e-58224
NC_004459:1679335:168362916836291684276648Vibrio vulnificus CMCP6 chromosome I, complete sequencehypothetical protein8e-57221
NC_004459:1679335:168432316843231684952630Vibrio vulnificus CMCP6 chromosome I, complete sequenceTransposase and inactivated derivatives4e-50199
NC_010658:3622610:362515736251573625468312Shigella boydii CDC 3083-94, complete genomeIS4 ORF3e-46186
NC_015424:2462522:246967924696792470422744Aeromonas veronii B565 chromosome, complete genomeputative IS4 transposase; KpLE2 phage-like element9e-45181
NC_015957:196000:2076502076502090081359Streptomyces violaceusniger Tu 4113 chromosome, complete genometransposase IS4 family protein1e-32141
NC_009921:7660795:7674205767420576754671263Frankia sp. EAN1pec, complete genometransposase IS4 family protein1e-32141
NC_009921:7660795:7677440767744076787021263Frankia sp. EAN1pec, complete genometransposase IS4 family protein1e-32141
NC_009921:3255833:3272508327250832737701263Frankia sp. EAN1pec, complete genometransposase IS4 family protein1e-32140
NC_009921:6691089:6701579670157967028411263Frankia sp. EAN1pec, complete genometransposase IS4 family protein1e-32140
NC_015422:4508028:4509693450969345108981206Alicycliphilus denitrificans K601 chromosome, complete genometransposase IS4 family protein5e-30132
NC_013093:1909305:1910513191051319117331221Actinosynnema mirum DSM 43827, complete genometransposase IS4 family protein1e-29131
NC_004369:41236:4297842978441921215Corynebacterium efficiens YS-314, complete genomehypothetical protein2e-29130
NC_004369:1268956:1282157128215712833711215Corynebacterium efficiens YS-314, complete genomeputative transposase2e-29130
NC_019673:3253650:3265193326519332664581266Saccharothrix espanaensis DSM 44229 complete genomeTransposase, IS4 family2e-29130
NC_019673:1384795:1399984139998414012491266Saccharothrix espanaensis DSM 44229 complete genomeTransposase, IS4 family6e-29129
NC_019673:8057941:8062858806285880641231266Saccharothrix espanaensis DSM 44229 complete genomeTransposase, IS4 family6e-29129
NC_015656:2795784:2804695280469528059301236Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28128
NC_015656:4850833:4855454485545448566891236Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28128
NC_015656:3232809:3239387323938732406221236Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28128
NC_015656:3300747:3306809330680933080441236Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28128
NC_016109:5768000:5795206579520657964471242Kitasatospora setae KM-6054, complete genomeputative transposase8e-29128
NC_015656:632960:6453346453346465961263Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28127
NC_015656:632960:6491266491266503881263Frankia symbiont of Datisca glomerata chromosome, complete genometransposase IS4 family protein1e-28127
NC_019673:2051363:2104510210451021057841275Saccharothrix espanaensis DSM 44229 complete genomeTransposase, IS4 family2e-28127
NC_004369:437594:4467754467754479621188Corynebacterium efficiens YS-314, complete genomehypothetical protein3e-28126
NC_009254:700891:7008917008917020991209Burkholderia vietnamiensis G4 chromosome 3, complete sequencetransposase, IS4 family protein6e-27122
NC_009255:213245:2203062203062215141209Burkholderia vietnamiensis G4 chromosome 2, complete sequencetransposase, IS4 family protein6e-27122
NC_009256:2945059:2946142294614229473501209Burkholderia vietnamiensis G4 chromosome 1, complete sequencetransposase, IS4 family protein6e-27122
NC_003155:365500:3710093710093726371629Streptomyces avermitilis MA-4680, complete genomeIS4 family transposase3e-26120
NC_018691:318662:3297063297063311331428Alcanivorax dieselolei B5 chromosome, complete genomePutative transposase, IS4 family9e-26118
NC_007777:2543475:2556883255688325581211239Frankia sp. CcI3, complete genometransposase, IS42e-25117
NC_008027:5576458:5584103558410355854881386Pseudomonas entomophila L48, complete genometransposase, IS4 family1e-24114
NC_009953:3509229:3529981352998135313361356Salinispora arenicola CNS-205 chromosome, complete genometransposase IS4 family protein1e-24114
NC_009921:4035225:4059514405951440607791266Frankia sp. EAN1pec, complete genometransposase IS4 family protein2e-24113
NC_016943:1037000:1049565104956510509021338Blastococcus saxobsidens DD2, complete genometransposase9e-23108
NC_015635:4097711:4123611412361141247921182Microlunatus phosphovorus NM-1, complete genomeputative transposase1e-22108
NC_015635:5222000:5235067523506752362811215Microlunatus phosphovorus NM-1, complete genomeputative transposase1e-22108
NC_015635:2001539:2008401200840120096151215Microlunatus phosphovorus NM-1, complete genomeputative transposase for insertion sequence element1e-22108
NC_015422:4508028:4545748454574845471271380Alicycliphilus denitrificans K601 chromosome, complete genometransposase IS4 family protein7e-22105
NC_015635:1906790:1911284191128419124231140Microlunatus phosphovorus NM-1, complete genomeputative transposase6e-22105
NC_015410:3093465:3106275310627531076541380Pseudomonas mendocina NK-01 chromosome, complete genomeIS4 family transposase3e-2099.8
NC_007948:1695500:1712930171293017143061377Polaromonas sp. JS666, complete genometransposase, IS42e-1997.1
NC_009921:2565640:257536525753652576321957Frankia sp. EAN1pec, complete genomeinsertion element conserved hypothetical protein5e-1892.8
NC_009921:6691089:6705062670506267063391278Frankia sp. EAN1pec, complete genometransposase IS4 family protein1e-1791.7
NC_013716:1178383:118878511887851189279495Citrobacter rodentium ICC168, complete genome4e-1686.3
NC_004547:913553:921906921906922199294Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeputative transposase (partial)1e-1584.7
NC_015556:130437:146600146600147196597Pseudomonas fulva 12-X chromosome, complete genome4e-1479.7
NC_019940:3660754:3669951366995136711861236Thioflavicoccus mobilis 8321 chromosome, complete genometransposase family protein5e-1479.3
NC_009953:4748147:475778747577874758389603Salinispora arenicola CNS-205 chromosome, complete genomehypothetical protein7e-1479
NC_013716:1178383:118989111898911190355465Citrobacter rodentium ICC168, complete genome1e-1377.8
NC_011768:79297:8647786477877451269Desulfatibacillum alkenivorans AK-01, complete genometransposase IS4 family protein5e-1375.9
NC_019902:27574:275742757428518945Thioalkalivibrio nitratireducens DSM 14787, complete genomeprotein containing transposase DDE domain9e-1272
NC_003155:365500:3686203686203696211002Streptomyces avermitilis MA-4680, complete genomeIS4 family transposase2e-1171.2
NC_015663:770485:775341775341775568228Enterobacter aerogenes KCTC 2190 chromosome, complete genomeISCro3 transposase6e-1168.9
NC_019673:6298342:6306803630680363079931191Saccharothrix espanaensis DSM 44229 complete genomeTransposase, IS4 family1e-1068.2
NC_011901:2983555:2990315299031529915651251Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completetransposase, IS4 family3e-1066.6
NC_009656:115390:1249551249551262261272Pseudomonas aeruginosa PA7 chromosome, complete genometransposase DDE domain-containing protein4e-1066.6
NC_007948:517893:519384519384519866483Polaromonas sp. JS666, complete genome5e-0962.8
NC_015214:437733:4674624674624688231362Lactobacillus acidophilus 30SC chromosome, complete genomeIS4 family transposase1e-0861.6
NC_016616:2644883:2665449266544926666121164Dechlorosoma suillum PS chromosome, complete genome2e-0757.4
NC_003155:365500:369344369344370132789Streptomyces avermitilis MA-4680, complete genomeIS4 family transposase2e-0654.3
NC_015957:6859259:687579368757936876398606Streptomyces violaceusniger Tu 4113 chromosome, complete genome2e-0654.3
NC_007413:3168931:3183812318381231851311320Anabaena variabilis ATCC 29413, complete genomeTransposase, IS45e-0652.8