Pre_GI: BLASTP Hits

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Query: NC_008258:269806:274041 Shigella flexneri 5 str. 8401, complete genome

Start: 274041, End: 274544, Length: 504

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004337:309833:324465324465324899435Shigella flexneri 2a str. 301, complete genomeputative phage tail fibre protein3e-73273
NC_004741:310382:316960316960317421462Shigella flexneri 2a str. 2457T, complete genomeputative phage tail fibre protein1e-71268
NC_007712:3067000:307497130749713075399429Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein3e-28124
NC_020064:871338:878066878066878491426Serratia marcescens FGI94, complete genomeCaudovirales tail fiber assembly protein8e-22102
NC_010102:1829357:184176318417631842170408Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein6e-2096.7
NC_003198:4453457:448272144827214483128408Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative phage tail fibre protein8e-2096.3
NC_010102:1779707:180070718007071801114408Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein8e-1992.8
NC_013892:992811:101244310124431012859417Xenorhabdus bovienii SS-2004 chromosome, complete genomeCPS-53 (KpLE1) prophage; tail fiber assembly1e-1892.4
NC_009436:1141376:115196011519601152382423Enterobacter sp. 638, complete genomephage tail assembly chaperone gp384e-1684
NC_007712:4023516:403166940316694032190522Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein6e-1683.6
NC_012962:4942000:494418649441864944638453Photorhabdus asymbiotica, complete genometail fiber assembly protein homolog from lambdoid prophage dlp123e-1477.8
NC_007712:1182518:119294511929451193556612Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein7e-1373.2
NC_011205:1391971:139546013954601396029570Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853phage tail assembly protein2e-1272
NC_011274:1299475:130654113065411307110570Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91phage tail fiber assembly protein2e-1271.6
NC_011294:1220526:124264112426411242934294Salmonella enterica subsp. enterica serovar Enteritidis str3e-1271.2
AC_000091:558920:580757580757581320564Escherichia coli W3110 DNA, complete genome3e-1271.2
NC_000913:558920:580757580757581320564Escherichia coli K12, complete genomeDLP12 prophage; predicted tail fiber assembly protein (pseudogene)3e-1271.2
NC_013941:733286:740261740261740845585Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeTail fiber assembly protein3e-1271.2
NC_010473:498252:520215520215520652438Escherichia coli str. K-12 substr. DH10B, complete genome3e-1270.9
NC_010473:623810:633475633475633912438Escherichia coli str. K-12 substr. DH10B, complete genome3e-1270.9
NC_011415:644811:652003652003652578576Escherichia coli SE11 chromosome, complete genomeputative phage tail assembly protein3e-1270.9
NC_013361:649518:657331657331657903573Escherichia coli O26:H11 str. 11368 chromosome, complete genometail fiber assembly protein5e-1270.1
NC_014500:177824:188977188977189354378Dickeya dadantii 3937 chromosome, complete genomeputative tail fiber assembly protein1e-1169.3
NC_013961:3413011:342337834233783423671294Erwinia amylovora, complete genomeTail fiber assembly protein homolog from lambdoid prophage DLP121e-1169.3
NC_013353:604719:611775611775612338564Escherichia coli O103:H2 str. 12009, complete genometail fiber assembly protein1e-1168.9
AP010958:604719:611775611775612338564Escherichia coli O103:H2 str. 12009 DNA, complete genomeputative tail fiber assembly protein1e-1168.9
NC_011751:1377457:139651413965141397098585Escherichia coli UMN026 chromosome, complete genomeputative tail fiber chaperone; Qin prophage2e-1168.6
NC_013971:335247:347714347714348004291Erwinia amylovora ATCC 49946 chromosome, complete genome3e-1167.8
NC_011294:1006630:101675710167571017338582Salmonella enterica subsp. enterica serovar Enteritidis strphage tail fiber assembly protein3e-1167.8
NC_011205:1107998:111738411173841117965582Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853tail fiber assembly like-protein3e-1167.8
NC_009800:2788164:279908627990862799670585Escherichia coli HS, complete genometail fiber assembly protein5e-1167
NC_011740:2737467:275506527550652755649585Escherichia fergusonii ATCC 35469, complete genomeputative tail fibre chaperone; Qin prophage7e-1166.6
NC_010473:1712984:172195917219591722534576Escherichia coli str. K-12 substr. DH10B, complete genomeQin prophage; predicted tail fibre assembly protein9e-1166.2
AC_000091:1627049:163602416360241636599576Escherichia coli W3110 DNA, complete genomepredicted tail fibre assembly protein9e-1166.2
NC_000913:1625500:163233416323341632909576Escherichia coli K12, complete genomeQin prophage; predicted tail fibre assembly protein9e-1166.2
NC_012759:1517500:152439315243931524968576Escherichia coli BW2952 chromosome, complete genomeQin prophage; tail fiber assembly protein9e-1166.2
NC_011080:2722492:273336927333692733947579Salmonella enterica subsp. enterica serovar Newport str. SL254,phage tail assembly protein8e-1166.2
NC_003197:2720726:273333727333372733915579Salmonella typhimurium LT2, complete genomephage tail assembly-like protein8e-1166.2
NC_016810:2719779:273102427310242731602579Salmonella enterica subsp. enterica serovar Typhimurium strDNA Binding protein8e-1166.2
NC_016856:2773995:278486627848662785444579Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sphage tail assembly-like protein8e-1166.2
NC_016857:2719779:273102427310242731602579Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74phage tail assembly-like protein8e-1166.2
NC_016860:2716152:272874527287452729323579Salmonella enterica subsp. enterica serovar Typhimurium strphage tail assembly protein8e-1166.2
NC_016863:2721826:273307127330712733649579Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1phage tail assembly-like protein8e-1166.2
NC_017046:2717810:273040327304032730981579Salmonella enterica subsp. enterica serovar Typhimurium str. 798DNA Binding protein8e-1166.2
NC_004431:1352906:137255413725541372820267Escherichia coli CFT073, complete genomeHypothetical protein ylcE1e-1065.9
NC_016856:1326503:132894413289441329528585Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sphage tail assembly-like protein1e-1065.9
NC_014228:3282500:331458733145873315018432Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein1e-1065.9
NC_007613:1353500:137279113727911373354564Shigella boydii Sb227, complete genomeputative tail fiber assembly protein1e-1065.5
NC_017328:2090679:210082021008202101089270Shigella flexneri 2002017 chromosome, complete genomeputative bacteriophage protein2e-1065.5
NC_004741:2009769:202189520218952022164270Shigella flexneri 2a str. 2457T, complete genomeputative bacteriophage protein2e-1065.5
NC_008258:2045000:205388620538862054155270Shigella flexneri 5 str. 8401, complete genomehypothetical bacteriophage protein2e-1065.5
NC_011751:1377457:139787813978781398144267Escherichia coli UMN026 chromosome, complete genomeputative tail fiber assembly protein3e-1064.3
NC_005815:61148:201820182626609Yersinia pestis biovar Microtus str. 91001 plasmid pMT1, completephage lambda-related tail assembly protein G5e-1063.9
NC_008118:56777:202220222630609Yersinia pestis Nepal516 plasmid pMT, complete sequencehypothetical protein5e-1063.9
NC_016856:1957263:1974881197488119759391059Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sphage side tail fiber assembly protein5e-1063.9
NC_011094:1923870:1940354194035419416821329Salmonella enterica subsp. enterica serovar Schwarzengrund strside tail fiber protein4e-1063.9
NC_003197:1945858:196347619634761964357882Salmonella typhimurium LT2, complete genomephage-tail assembly-like protein8e-1063.2
NC_016810:1903426:192104419210441921925882Salmonella enterica subsp. enterica serovar Typhimurium strPhage Tail Assembly Protein8e-1063.2
NC_016857:1903426:192104419210441921925882Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74phage-tail assembly-like protein8e-1063.2
NC_016863:1905454:192307219230721923953882Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1phage-tail assembly-like protein8e-1063.2
NC_017046:1902788:192040719204071921288882Salmonella enterica subsp. enterica serovar Typhimurium str. 798Phage Tail Assembly Protein8e-1063.2
NC_011083:1993672:201249820124982012734237Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,putative Tail fiber assembly protein homolog from lambdoid prophage2e-0961.6
NC_011080:1944226:196848219684821969363882Salmonella enterica subsp. enterica serovar Newport str. SL254,caudovirales tail fibre assembly protein3e-0961.2
NC_016831:1690811:170841617084161708652237Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein8e-0959.7
NC_014228:3022903:303488630348863035419534Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein3e-0857.8
NC_011415:644811:655089655089655394306Escherichia coli SE11 chromosome, complete genomehypothetical protein3e-0857.8
NC_013941:733286:741625741625741930306Escherichia coli O55:H7 str. CB9615 chromosome, complete genometail fiber assembly protein3e-0857.8
NC_013361:649518:658683658683658988306Escherichia coli O26:H11 str. 11368 chromosome, complete genome3e-0857.8
AP010958:604719:614851614851615156306Escherichia coli O103:H2 str. 12009 DNA, complete genomehypothetical protein3e-0857.8
NC_013353:604719:614851614851615156306Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein3e-0857.8
NC_011205:2137696:214882021488202149389570Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853tail fiber assembly protein2e-0755.5
NC_011294:2009388:202051320205132021082570Salmonella enterica subsp. enterica serovar Enteritidis strphage tail protein2e-0755.5
NC_016856:2085283:209563220956322096201570Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative tail fiber assembly protein2e-0755.5
NC_016863:2029340:204382420438242044393570Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein2e-0755.5
NC_017046:2026672:204115620411562041725570Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage tail protein2e-0755.5
NC_010473:2548946:256086425608642561304441Escherichia coli str. K-12 substr. DH10B, complete genomeCPS-53 (KpLE1) prophage; conserved protein1e-0755.5
AC_000091:2462461:247652324765232476963441Escherichia coli W3110 DNA, complete genomehypothetical protein1e-0755.5
NC_000913:2455037:246909924690992469539441Escherichia coli K12, complete genomeCPS-53 (KpLE1) prophage; conserved protein1e-0755.5
NC_012759:2342986:235490423549042355344441Escherichia coli BW2952 chromosome, complete genomeCPS-53 (KpLE1) prophage protein1e-0755.5
NC_016810:2027311:204179520417952042394600Salmonella enterica subsp. enterica serovar Typhimurium strputative bacteriophage tail protein1e-0755.5
NC_010102:931055:940063940063940638576Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein1e-0755.5
NC_011094:2115750:212749021274902128065576Salmonella enterica subsp. enterica serovar Schwarzengrund strtail fiber assembly protein1e-0755.5
NC_012962:2587756:259104625910462591669624Photorhabdus asymbiotica, complete genometail fiber assembly protein homolog from lambdoid prophage e143e-0754.7
NC_016857:2027311:204179520417952042121327Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74tail fiber assembly protein2e-0754.7
NC_014228:3282500:331415933141593314461303Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein2e-0754.7
NC_012962:2587756:258914625891462589769624Photorhabdus asymbiotica, complete genomesimilarities with putative tail fiber protein of prophage5e-0753.9
NC_012559:1888000:190339419033941904245852Laribacter hongkongensis HLHK9, complete genomeHsdM1e-0652.8
NC_012751:899394:915111915111915647537Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completephage tail assembly chaperone1e-0652.4
NC_011205:1391971:140375214037521404198447Salmonella enterica subsp. enterica serovar Dublin str. CT_020218535e-0650.4
NC_012880:2480000:248311324831132483727615Dickeya dadantii Ech703, complete genometail assembly chaperone gp389e-0649.7