Pre_GI: BLASTP Hits

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Query: NC_008258:269806:271845 Shigella flexneri 5 str. 8401, complete genome

Start: 271845, End: 272903, Length: 1059

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011750:2928990:2940628294062829416861059Escherichia coli IAI39 chromosome, complete genomeputative baseplate J-like phage protein0704
NC_011742:2823000:2841141284114128421991059Escherichia coli S88 chromosome, complete genomebaseplate J-like phage protein0698
NC_007946:2894793:2908804290880429098621059Escherichia coli UTI89, complete genomebacteriophage V tail protein0698
NC_011740:621408:6234476234476245051059Escherichia fergusonii ATCC 35469, complete genomeputative baseplate J-like phage protein0698
NC_008563:2909945:2923831292383129248891059Escherichia coli APEC O1, complete genomebacteriophage V tail protein0696
NC_009436:2776410:2790564279056427916221059Enterobacter sp. 638, complete genomebaseplate J family protein1e-159562
AC_000091:1191353:120783712078371208499663Escherichia coli W3110 DNA, complete genomehypothetical protein5e-122437
NC_000913:1188999:120548312054831206145663Escherichia coli K12, complete genomee14 prophage; conserved protein5e-122437
NC_011094:2115750:2130186213018621312651080Salmonella enterica subsp. enterica serovar Schwarzengrund strtail protein1e-121436
NC_011294:2009388:2023221202322120243001080Salmonella enterica subsp. enterica serovar Enteritidis strphage protein9e-121433
NC_011205:2137696:2151528215152821526071080Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853tail protein9e-121433
NC_010102:1779707:1802789180278918038681080Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein1e-120433
NC_007712:1182518:1195147119514711962171071Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein2e-106385
NC_002937:255790:2580502580502591111062Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetail protein, putative7e-56218
NC_002937:2933000:2951774295177429528351062Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetail protein, putative9e-56217
NC_016810:2027311:204505920450592045604546Salmonella enterica subsp. enterica serovar Typhimurium strputative bacteriophage protein1e-53210
NC_016863:2029340:204708820470882047612525Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein1e-53210
NC_017046:2026672:204442020444202044944525Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage protein1e-53210
NC_017046:2026672:204386420438642044385522Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage protein2e-52206
NC_016810:2027311:204450320445032045024522Salmonella enterica subsp. enterica serovar Typhimurium strputative bacteriophage protein2e-52206
NC_016863:2029340:204653220465322047053522Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein6e-52204
NC_002947:4362271:4384490438449043855331044Pseudomonas putida KT2440, complete genomephage FluMu protein gp474e-44178
NC_015733:1398083:1398968139896813999991032Pseudomonas putida S16 chromosome, complete genomephage FluMu protein gp475e-41168
NC_000907:1568867:1589241158924115903081068Haemophilus influenzae Rd KW20, complete genomehypothetical protein6e-40164
NC_012660:4558122:458160345816034582274672Pseudomonas fluorescens SBW25 chromosome, complete genome2e-38160
NC_014228:3282500:3311254331125433123271074Xenorhabdus nematophila ATCC 19061, complete genomeputative bacteriophage protein8e-35147
NC_009800:2049346:2070534207053420716821149Escherichia coli HS, complete genomeputative baseplate J protein1e-31137
NC_011365:592256:6301736301736312641092Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomebaseplate J family protein2e-27123
NC_012751:899394:912848912848913759912Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completephage baseplate J-like protein2e-2099.8
NC_012559:1888000:189030918903091891148840Laribacter hongkongensis HLHK9, complete genomeProbable phage FluMu protein gp475e-1995.5
NC_002927:3827211:3837547383754738386171071Bordetella bronchiseptica RB50, complete genomeputative phage tail protein5e-1892.4
NC_009633:2592000:2597032259703225981681137Alkaliphilus metalliredigens QYMF chromosome, complete genomebaseplate J family protein2e-1790.5
NC_011837:1935294:1939120193912019402501131Clostridium kluyveri NBRC 12016, complete genomehypothetical protein3e-1789.4
NC_009706:2003194:2007608200760820087381131Clostridium kluyveri DSM 555 chromosome, complete genomeXkdT-like protein3e-1789.4
NC_009706:1935418:1939244193924419403741131Clostridium kluyveri DSM 555 chromosome, complete genomeXkdT related phage protein3e-1789.4
NC_012563:2566500:2570289257028925714191131Clostridium botulinum A2 str. Kyoto, complete genomeputative baseplate J-like protein2e-1584
NC_014652:801653:8283658283658294471083Caldicellulosiruptor hydrothermalis 108 chromosome, completebaseplate j family protein1e-1480.9
NC_009706:3291330:3318380331838033195071128Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-1480.1
NC_011837:3226500:3249882324988232509941113Clostridium kluyveri NBRC 12016, complete genomehypothetical protein3e-1479.7
NC_009495:2479465:2482266248226624833961131Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-1377.4
NC_016628:373815:3959663959663970121047Vibrio furnissii NCTC 11218 chromosome 2, complete sequencephage protein5e-1375.5
NC_010674:2817651:2827773282777328288941122Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein2e-1273.6
NC_018604:305957:3438113438113448571047Brachyspira pilosicoli WesB complete genomehypothetical protein4e-1169.3
NC_010674:1986000:1992898199289819939651068Clostridium botulinum B str. Eklund 17B, complete genomeputative conserved hypothetical protein5e-1168.9
NC_014976:627935:6541406541406551861047Bacillus subtilis BSn5 chromosome, complete genomeputative phage capsid assembly protein2e-1067.4
NC_016077:1944000:1965038196503819661051068Acidaminococcus intestini RyC-MR95 chromosome, complete genomehypothetical protein2e-1066.6
NC_013406:6052913:6064990606499060661441155Paenibacillus sp. Y412MC10 chromosome, complete genomeBaseplate J family protein3e-1066.2
NC_000964:1330000:1340663134066313417091047Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein4e-1066.2
NC_016077:1388775:1398561139856113995801020Acidaminococcus intestini RyC-MR95 chromosome, complete genomehypothetical protein4e-1066.2
NC_016047:261304:2689852689852700311047Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein6e-1065.5
NC_013406:6052913:6052913605291360539711059Paenibacillus sp. Y412MC10 chromosome, complete genomeBaseplate J family protein8e-1065.1
UCMB5137:861734:8783668783668794121047Bacillus atrophaeus UCMB-5137BATR1942_04035; putative phage capsid assembly protein; skin element; (location [796051:797098] strand +); from Bacillus atrophaeus 1942, complete gen1e-0964.7
NC_014976:3546884:3555229355522935562751047Bacillus subtilis BSn5 chromosome, complete genomeputative base plate assembly protein; putative PBSX prophage protein1e-0964.7
NC_013216:4404085:4418636441863644197661131Desulfotomaculum acetoxidans DSM 771, complete genomeBaseplate J family protein2e-0963.9
NC_013517:1501276:1515672151567215167631092Sebaldella termitidis ATCC 33386, complete genomeUncharacterized phage Mu protein gp47-like protein1e-0963.9
NC_019896:2719456:2727578272757827286241047Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completePhage-like element PBSX protein XkdT2e-0963.5
NC_014483:1179286:1191720119172011928711152Paenibacillus polymyxa E681 chromosome, complete genomehypothetical protein4e-0962.8
NC_020244:1335531:1344485134448513455311047Bacillus subtilis XF-1, complete genomehypothetical protein5e-0962.4
NC_016047:1435961:1447604144760414486501047Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein5e-0962.4
NC_014479:1291500:1299525129952513005711047Bacillus subtilis subsp. spizizenii str. W23 chromosome, completeputative base plate assembly protein; PBSZ phage6e-0962
NC_014376:1472304:1506656150665615076661011Clostridium saccharolyticum WM1 chromosome, complete genomeBaseplate J family protein7e-0962
NC_017195:1308730:1318221131822113192671047Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completehypothetical protein2e-0860.5
NC_020291:795500:8399728399728410601089Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomebaseplate J family protein2e-0860.5
NC_016641:2950000:2960522296052229616731152Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein2e-0860.1
NC_012673:1:3613136131372791149Exiguobacterium sp. AT1b, complete genomeBaseplate J family protein2e-0860.1
NC_018664:1573925:1581997158199715831241128Clostridium acidurici 9a chromosome, complete genomeputative baseplate J family protein4e-0859.3
NC_018515:3411276:3424912342491234259491038Desulfosporosinus meridiei DSM 13257 chromosome, complete genomephage Mu protein gp47-like protein5e-0858.9
NC_010723:915697:9292549292549303121059Clostridium botulinum E3 str. Alaska E43, complete genomehypothetical protein9e-0858.2
NC_007519:3355768:3356201335620133573641164Desulfovibrio alaskensis G20 chromosome, complete genomebaseplate assembly protein9e-0858.2
NC_009617:1085000:1103558110355811046251068Clostridium beijerinckii NCIMB 8052 chromosome, complete genomebaseplate J family protein1e-0758.2
NC_020291:795500:8535298535298545721044Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage Mu protein-like protein gp471e-0551.2