Pre_GI: BLASTP Hits

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Query: NC_008258:2542863:2559279 Shigella flexneri 5 str. 8401, complete genome

Start: 2559279, End: 2559686, Length: 408

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:2586171:260110326011032601510408Shigella flexneri 2002017 chromosome, complete genomeEthanolamine utilization protein EutS4e-74275
NC_004741:2526421:254159825415982542005408Shigella flexneri 2a str. 2457T, complete genomehypothetical protein4e-74275
NC_004337:2548288:256346525634652563872408Shigella flexneri 2a str. 301, complete genomehypothetical protein4e-74275
NC_009253:1381401:138225713822571382601345Desulfotomaculum reducens MI-1 chromosome, complete genomemicrocompartments protein6e-33139
NC_014538:985339:100510410051041005445342Thermoanaerobacter sp. X513 chromosome, complete genomemicrocompartments protein2e-32137
NC_004557:2289135:230736723073672307720354Clostridium tetani E88, complete genomeethanolamine utilization protein eutS7e-30129
NC_013192:63111:830078300783357351Leptotrichia buccalis DSM 1135, complete genomemicrocompartments protein1e-29127
NC_009633:286677:290395290395290745351Alkaliphilus metalliredigens QYMF chromosome, complete genomemicrocompartments protein2e-29127
NC_011740:2072173:207515520751552075529375Escherichia fergusonii ATCC 35469, complete genomeputative propanediol utilization protein: polyhedral bodies pduU2e-29127
NC_009922:2556033:257171225717122572065354Alkaliphilus oremlandii OhILAs, complete genomemicrocompartments protein2e-29127
NC_014019:3543389:355934835593483559689342Bacillus megaterium QM B1551 chromosome, complete genomeethanolamine utilization protein EutS5e-29126
NC_003366:1091766:109566910956691096019351Clostridium perfringens str. 13, complete genomepropanediol utilization protein4e-29126
NC_008261:1048515:105242110524211052771351Clostridium perfringens ATCC 13124, complete genomeethanolamine utilization protein EutS4e-29126
NC_017179:2067015:207066220706622071012351Clostridium difficile BI1, complete genomeethanolamine/propanediol utilization protein6e-29125
NC_013315:2059007:206265420626542063004351Clostridium difficile CD196 chromosome, complete genomeethanolamine/propanediol utilization protein6e-29125
NC_014614:284005:289369289369289713345Clostridium sticklandii, complete genomeputative carboxysome-like ethanolaminosome structural protein with role in ethanol utilization9e-29125
NC_015275:4493500:450587845058784506234357Clostridium lentocellum DSM 5427 chromosome, complete genomemicrocompartments protein1e-28125
NC_012491:5914500:593608659360865936427342Brevibacillus brevis NBRC 100599, complete genomehypothetical protein2e-28124
NC_010674:1496500:150697615069761507329354Clostridium botulinum B str. Eklund 17B, complete genomeethanolamine utilization protein EutS1e-27121
NC_012563:2384500:239736823973682397721354Clostridium botulinum A2 str. Kyoto, complete genomeethanolamine utilization protein EutS homolog6e-27119
NC_009495:2244774:225396422539642254317354Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeethanolamine utilization protein EutS-like protein6e-27119
NC_009697:2173000:218260621826062182959354Clostridium botulinum A str. ATCC 19397 chromosome, completeethanolamine utilization protein EutS-like protein6e-27119
NC_009698:2171151:218282521828252183178354Clostridium botulinum A str. Hall chromosome, complete genomeethanolamine utilization protein EutS-like protein6e-27119
NC_009699:2287893:230316523031652303518354Clostridium botulinum F str. Langeland chromosome, complete genomeethanolamine utilization protein EutS-like protein6e-27119
NC_004557:1553000:156186915618691562222354Clostridium tetani E88, complete genomeethanolamine utilization protein eutS5e-27119
NC_012658:2295536:231133423113342311687354Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative ethanolamine utilization protein EutS2e-26117
NC_009633:3933941:394835439483543948707354Alkaliphilus metalliredigens QYMF chromosome, complete genomemicrocompartments protein6e-26116
NC_016584:5625975:563889756388975639250354Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine utilization protein8e-26115
NC_014376:1586649:159390215939021594246345Clostridium saccharolyticum WM1 chromosome, complete genomemicrocompartments protein7e-26115
NC_009922:868262:872077872077872421345Alkaliphilus oremlandii OhILAs, complete genomemicrocompartments protein2e-25114
NC_016584:1998000:201799720179972018335339Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine utilization protein3e-25113
NC_007519:3240864:326039832603983260757360Desulfovibrio alaskensis G20 chromosome, complete genomeputative propanediol utilization protein PduU3e-24110
NC_014654:1113116:113370511337051134049345Halanaerobium sp. 'sapolanicus' chromosome, complete genomemicrocompartments protein3e-24110
NC_013517:1055854:112385111238511124198348Sebaldella termitidis ATCC 33386, complete genomemicrocompartments protein2e-24110
NC_016894:3329562:333924833392483339622375Acetobacterium woodii DSM 1030 chromosome, complete genomeputative propanediol utilization protein PduU9e-24108
NC_016048:1694631:169757416975741697957384Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein1e-23108
NC_009922:868262:869446869446869790345Alkaliphilus oremlandii OhILAs, complete genomemicrocompartments protein3e-23107
NC_014376:1586649:159132615913261591670345Clostridium saccharolyticum WM1 chromosome, complete genomemicrocompartments protein1e-22105
NC_010723:1465097:147718914771891477542354Clostridium botulinum E3 str. Alaska E43, complete genomeethanolamine utilization protein EutS homolog2e-22104
NC_018870:705900:717443717443717712270Thermacetogenium phaeum DSM 12270 chromosome, complete genomeethanolamine utilization protein EutS3e-22103
NC_010001:1488000:149295114929511493310360Clostridium phytofermentans ISDg, complete genomemicrocompartments protein1e-2098.2
NC_010001:1745089:175905317590531759394342Clostridium phytofermentans ISDg, complete genomemicrocompartments protein6e-1992.8
NC_017297:2288000:230346823034682303635168Clostridium botulinum F str. 230613 chromosome, complete genome2e-0651.2