Pre_GI: BLASTP Hits

Some Help

Query: NC_008258:2542863:2558787 Shigella flexneri 5 str. 8401, complete genome

Start: 2558787, End: 2559266, Length: 480

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004337:2548288:256297325629732563452480Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-90330
NC_004741:2526421:254110625411062541585480Shigella flexneri 2a str. 2457T, complete genomehypothetical protein3e-90330
NC_009253:1381401:138261913826191383053435Desulfotomaculum reducens MI-1 chromosome, complete genomeethanolamine utilization protein eutP1e-1788.6
NC_007519:3240864:325996132599613260383423Desulfovibrio alaskensis G20 chromosome, complete genomeethanolamine utilization protein-like5e-1786.7
NC_004557:2289135:230692223069222307356435Clostridium tetani E88, complete genomeethanolamine utilization protein eutP2e-1684.7
NC_012491:5914500:593564659356465936089444Brevibacillus brevis NBRC 100599, complete genomehypothetical protein2e-1581.3
NC_014019:3543389:355882635588263559323498Bacillus megaterium QM B1551 chromosome, complete genomeethanolamine utilization protein EutP2e-1478.2
NC_009922:868262:869807869807870250444Alkaliphilus oremlandii OhILAs, complete genomeethanolamine utilization protein, EutP5e-1476.6
NC_003366:1091766:109602310960231096457435Clostridium perfringens str. 13, complete genomepropanediol utilization protein8e-1476.3
NC_008261:1048515:105277510527751053209435Clostridium perfringens ATCC 13124, complete genomeethanolamine utilization protein, EutP2e-1375.1
NC_013517:1055854:112420311242031124637435Sebaldella termitidis ATCC 33386, complete genomeethanolamine utilization protein, EutP2e-1374.7
NC_008497:1575884:158233515823351582766432Lactobacillus brevis ATCC 367, complete genome5e-1373.6
NC_016584:1998000:201833620183362018785450Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine utilization protein6e-1373.2
NC_014376:1586649:159168715916871592127441Clostridium saccharolyticum WM1 chromosome, complete genomeethanolamine utilization protein, EutP6e-1373.2
NC_009633:286677:290757290757291185429Alkaliphilus metalliredigens QYMF chromosome, complete genomeethanolamine utilization protein, EutP9e-1372.8
NC_014654:1113116:113405111340511134485435Halanaerobium sp. 'sapolanicus' chromosome, complete genomeethanolamine utilization protein, EutP1e-1168.9
NC_017179:2067015:207102020710202071469450Clostridium difficile BI1, complete genomeethanolamine utilization protein EutP3e-1167.4
NC_013315:2059007:206301220630122063461450Clostridium difficile CD196 chromosome, complete genomeethanolamine/propanediol utilization protein3e-1167.4
NC_014538:985339:100545810054581005907450Thermoanaerobacter sp. X513 chromosome, complete genomeethanolamine utilization protein EutP1e-1065.9
NC_014614:284005:289739289739290170432Clostridium sticklandii, complete genomeEthanolamine utilization protein eutP2e-1065.1
NC_013192:63111:825708257083004435Leptotrichia buccalis DSM 1135, complete genomeethanolamine utilization protein, EutP1e-0962.4
NC_015275:4493500:450542545054254505874450Clostridium lentocellum DSM 5427 chromosome, complete genomeethanolamine utilization protein, EutP1e-0962.4
NC_011740:2072173:207553120755312075980450Escherichia fergusonii ATCC 35469, complete genomeconserved hypothetical protein; putative Propanediol utilization protein pduV5e-0960.1
NC_016048:1694631:169797216979721698505534Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein1e-0858.9
NC_016894:3329562:333873233387323339232501Acetobacterium woodii DSM 1030 chromosome, complete genomeethanolamine/propanediol utilization protein PduV34e-0857.4
NC_010674:1496500:150732615073261507784459Clostridium botulinum B str. Eklund 17B, complete genomelysine-sensitive aspartokinase III3e-0753.9
NC_016584:5625975:563846656384665638900435Desulfosporosinus orientis DSM 765 chromosome, complete genomeethanolamine utilization protein7e-0753.1
NC_010723:1465097:147753914775391477979441Clostridium botulinum E3 str. Alaska E43, complete genomeGTP-binding protein, EutP/PduV family1e-0652
NC_018870:705900:719392719392719898507Thermacetogenium phaeum DSM 12270 chromosome, complete genomeethanolamine/propanediol utilization protein2e-0651.6
NC_012658:2295536:231089123108912311337447Clostridium botulinum Ba4 str. 657 chromosome, complete genomeGTP-binding protein3e-0651.2
NC_009633:3933941:394790839479083948357450Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein8e-0649.7