Pre_GI: BLASTP Hits

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Query: NC_008258:1076922:1093901 Shigella flexneri 5 str. 8401, complete genome

Start: 1093901, End: 1094455, Length: 555

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_000913:1087062:109886310988631099417555Escherichia coli K12, complete genomehypothetical protein9e-103372
AC_000091:1083798:109988110998811100435555Escherichia coli W3110 DNA, complete genomehypothetical protein9e-103372
NC_010468:2809125:280971828097182810272555Escherichia coli ATCC 8739, complete genomecytoplasmic chaperone TorD family protein9e-103372
NC_004337:1065609:107452110745211075075555Shigella flexneri 2a str. 301, complete genomeputative oxidoreductase component2e-102370
NC_013716:1178383:119704111970411197595555Citrobacter rodentium ICC168, complete genomeputative chaperone4e-96349
NC_011094:1166271:118515611851561185710555Salmonella enterica subsp. enterica serovar Schwarzengrund strchaperone, TorD family protein6e-92336
NC_011147:1763681:176665617666561767210555Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein2e-91334
NC_011083:1216500:123119812311981231752555Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,chaperone, TorD family2e-91334
NC_003198:1117687:113712511371251137679555Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein2e-91334
NC_006511:1770000:177147317714731772027555Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein2e-91334
NC_003197:1207597:122684912268491227403555Salmonella typhimurium LT2, complete genomeputative oxidoreductase component2e-91334
NC_006905:1186895:120693512069351207489555Salmonella enterica subsp. enterica serovar Choleraesuis strparal putative oxidoreductase component2e-91334
NC_004631:1842050:184350418435041844058555Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein2e-91334
NC_011080:1209935:122863612286361229190555Salmonella enterica subsp. enterica serovar Newport str. SL254,chaperone, TorD family2e-91334
NC_011205:2137696:213959421395942140148555Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853chaperone, TorD family2e-91334
NC_011294:2009388:201128620112862011840555Salmonella enterica subsp. enterica serovar Enteritidis strhypothetical protein2e-91334
NC_017046:1164176:118306211830621183616555Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein2e-91334
NC_016863:1165232:118430211843021184856555Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative oxidoreductase2e-91334
NC_016860:1205282:122453512245351225089555Salmonella enterica subsp. enterica serovar Typhimurium strchaperone, TorD family protein2e-91334
NC_016857:1163919:118298911829891183543555Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative oxidoreductase2e-91334
NC_016856:1165941:118501111850111185565555Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative oxidoreductase2e-91334
NC_016832:1838220:184053918405391841093555Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein2e-91334
NC_016810:1163919:118298911829891183543555Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-91334
NC_012125:2646792:264824626482462648800555Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein2e-91334
NC_010067:1782998:178443417844341784988555Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein4e-91333
NC_010102:1979742:198120019812001981751552Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein5e-91333
NC_015968:1709680:171495817149581715512555Enterobacter asburiae LF7a chromosome, complete genomecytoplasmic chaperone TorD family protein3e-88323
NC_016514:1701273:170476517047651705319555Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YcdY8e-87319
NC_014121:2629075:264489726448972645451555Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completecytoplasmic chaperone TorD family protein1e-85315
NC_015663:3466471:350106435010643501618555Enterobacter aerogenes KCTC 2190 chromosome, complete genomeputative oxidoreductase component1e-84312
NC_011274:2044000:204403220440322044529498Salmonella enterica subsp. enterica serovar Gallinarum str. 287/912e-79295
NC_016816:2782373:278825527882552788824570Pantoea ananatis LMG 5342, complete genomecytoplasmic chaperone TorD family protein8e-69259
NC_017047:1796000:181141618114161812000585Rahnella aquatilis HX2 chromosome, complete genomecytoplasmic chaperone TorD family protein7e-68256
NC_009778:2227627:223627422362742236840567Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-67254
NC_010465:2383219:240234324023432402903561Yersinia pseudotuberculosis YPIII, complete genomecytoplasmic chaperone TorD family protein1e-66252
NC_010159:2546590:256560625656062566166561Yersinia pestis Angola, complete genomecytoplasmic chaperone, TorD family1e-66252
NC_004088:2491303:251047425104742511034561Yersinia pestis KIM, complete genomeoxidoreductase component1e-66252
NC_009381:1205900:122498712249871225547561Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-66252
NC_009708:2347350:236523923652392365799561Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeTorD family cytoplasmic chaperone1e-66252
NC_014029:2285323:230446223044622305022561Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-66252
NC_017160:2212806:223196122319612232521561Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-66252
NC_017168:3433804:345277034527703453330561Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-66252
NC_017265:2213500:223213822321382232698561Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-66252
NC_009053:393700:399573399573400142570Actinobacillus pleuropneumoniae L20, complete genomehypothetical protein2e-30131
NC_010939:405477:427285427285427854570Actinobacillus pleuropneumoniae serovar 7 str. AP76, completehypothetical protein2e-30131
NC_010278:398521:404403404403404972570Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,component of anaerobic dehydrogenase2e-30131
NC_016513:1924242:193381919338191934382564Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeTorD protein5e-29127
NC_013416:1588369:159788915978891598452564Aggregatibacter actinomycetemcomitans D11S-1, complete genomeTorD protein5e-29127
NC_017047:1551836:155276315527631553371609Rahnella aquatilis HX2 chromosome, complete genomecytoplasmic chaperone TorD family protein4e-1167.4
NC_015061:1598920:159984715998471600455609Rahnella sp. Y9602 chromosome, complete genomecytoplasmic chaperone TorD family protein4e-1167.4
NC_016818:1605918:160684516068451607453609Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completeputative component of anaerobic dehydrogenase7e-1063.5
NC_011147:4297513:430330043033004304004705Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein3e-0858.2
NC_009831:1539159:155485015548501555464615Shewanella sediminis HAW-EB3, complete genomecytoplasmic chaperone TorD family protein4e-0857.8
NC_004631:4381724:438546243854624386148687Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein4e-0857.8
NC_003198:4397074:440081244008124401498687Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein4e-0857.8
NC_016832:4368948:437277943727794373372594Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Oxidoreductase component4e-0857.8
NC_011274:4385039:439089543908954391548654Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91hypothetical protein7e-0857
NC_017046:4571833:457574445757444576337594Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein7e-0857
NC_016860:4649274:465318546531854653778594Salmonella enterica subsp. enterica serovar Typhimurium strputative anaerobic dehydrogenase component7e-0857
NC_011080:4543000:454691045469104547503594Salmonella enterica subsp. enterica serovar Newport str. SL254,oxidoreductase component7e-0857
NC_010102:4477836:448174744817474482340594Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein7e-0857
NC_016831:4367000:437110143711014371694594Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein7e-0857
NC_012125:4481808:448571944857194486312594Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein7e-0857
NC_003197:4551880:455573145557314556384654Salmonella typhimurium LT2, complete genomeputative anaerobic dehydrogenase component6e-0857
NC_011294:4409137:441298744129874413640654Salmonella enterica subsp. enterica serovar Enteritidis strhypothetical protein6e-0857
NC_016810:4573172:457702345770234577676654Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein6e-0857
NC_016856:4563435:456927345692734569926654Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative anaerobic dehydrogenase component6e-0857
NC_016857:4573173:457702445770244577677654Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative anaerobic dehydrogenase component6e-0857
NC_016863:4513106:451687945168794517532654Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative anaerobic dehydrogenase component6e-0857
NC_006905:4486433:449028444902844490937654Salmonella enterica subsp. enterica serovar Choleraesuis strputative component of anaerobic dehydrogenase6e-0857
NC_010939:1920781:192932819293281929933606Actinobacillus pleuropneumoniae serovar 7 str. AP76, completehypothetical protein1e-0756.6
NC_011149:4474012:447792344779234478516594Salmonella enterica subsp. enterica serovar Agona str. SL483,8e-0856.6
NC_011094:4442478:444632944463294446982654Salmonella enterica subsp. enterica serovar Schwarzengrund stroxidoreductase1e-0756.2
NC_004347:4541742:455705445570544557683630Shewanella oneidensis MR-1, complete genomehypothetical protein1e-0756.2
NC_011083:4547825:455173645517364552329594Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,2e-0755.8
NC_011205:4564645:457054345705434571136594Salmonella enterica subsp. enterica serovar Dublin str. CT_020218533e-0754.7
NC_009053:1895485:190402719040271904632606Actinobacillus pleuropneumoniae L20, complete genomehypothetical protein4e-0651.2